scholarly journals A network-based integration for understanding racial disparity in prostate cancer

2022 ◽  
Vol 17 ◽  
pp. 101327
Author(s):  
Baoyi Zhang ◽  
Kevin Yao ◽  
Chao Cheng
Cancers ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2651 ◽  
Author(s):  
Sirin Saranyutanon ◽  
Sachin Kumar Deshmukh ◽  
Santanu Dasgupta ◽  
Sachin Pai ◽  
Seema Singh ◽  
...  

We have witnessed noteworthy progress in our understanding of prostate cancer over the past decades. This basic knowledge has been translated into efficient diagnostic and treatment approaches leading to the improvement in patient survival. However, the molecular pathogenesis of prostate cancer appears to be complex, and histological findings often do not provide an accurate assessment of disease aggressiveness and future course. Moreover, we also witness tremendous racial disparity in prostate cancer incidence and clinical outcomes necessitating a deeper understanding of molecular and mechanistic bases of prostate cancer. Biological research heavily relies on model systems that can be easily manipulated and tested under a controlled experimental environment. Over the years, several cancer cell lines have been developed representing diverse molecular subtypes of prostate cancer. In addition, several animal models have been developed to demonstrate the etiological molecular basis of the prostate cancer. In recent years, patient-derived xenograft and 3-D culture models have also been created and utilized in preclinical research. This review is an attempt to succinctly discuss existing information on the cellular and molecular progression of prostate cancer. We also discuss available model systems and their tested and potential utility in basic and preclinical prostate cancer research.


2019 ◽  
Vol 51 (8) ◽  
pp. 1343-1348 ◽  
Author(s):  
Amr Mahran ◽  
Kirtishri Mishra ◽  
Laura Bukavina ◽  
Fredrick Schumacher ◽  
Anna Quian ◽  
...  

2018 ◽  
Vol 16 (5) ◽  
pp. e1073-e1076 ◽  
Author(s):  
Alireza Aminsharifi ◽  
Thomas J. Polascik ◽  
Matvey Tsivian ◽  
Ariel Schulman ◽  
Efrat Tsivian ◽  
...  

2018 ◽  
Author(s):  
Yutaka Hashimoto ◽  
Masrisa Shiina ◽  
Taku Kato ◽  
Soichiro Yamamura ◽  
Yuichiro Tanaka ◽  
...  

2016 ◽  
Author(s):  
Dev Karan ◽  
Seema Dubey ◽  
Jo Wick ◽  
Ossama Tawfik ◽  
Guru Sonpavde ◽  
...  

2016 ◽  
Vol 23 (1) ◽  
pp. 47-51 ◽  
Author(s):  
Ballington L. Kinlock ◽  
Roland J. Thorpe ◽  
Daniel L. Howard ◽  
Janice V. Bowie ◽  
Louie E. Ross ◽  
...  

2019 ◽  
Vol 12 (9) ◽  
pp. 585-598 ◽  
Author(s):  
Yutaka Hashimoto ◽  
Marisa Shiina ◽  
Pritha Dasgupta ◽  
Priyanka Kulkarni ◽  
Taku Kato ◽  
...  

2012 ◽  
Author(s):  
Krzysztof Moroz ◽  
Zakaria Abd Elmageed ◽  
Sudesh Srivastav ◽  
Krishnarao Moparty ◽  
Krishnarao Moparty ◽  
...  

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