161 Biosensor in cardiology. T-care project: a preliminary study on innovative wearable non-invasive telemonitoring system

Abstract The demographic trend evolution and the modification of health needs highlight the requirement for a novel organization of the healthcare system. Telemedicine is a technological tool that allows a knockdown of geographic barriers being useful in the management of remote patient assistance. Telemedicine is roughly applied in different cardiology’s areas, from telemetric to implantable devices (loop recorders) in order to monitor cardiac rate, cardiac rhythm variations, and the onset of arrhythmic events. The aim of the present study is to assess the validity of wearable devices (T-shirt equipped with biosensors and bands with photopletimographic system) in monitoring EKG, cardiac rate, and pulse oximetry. We enrolled 38 patients, 25 of whom admitted to the Cardiology Unit, University of Bari. Main characteristics of the sample are listed in Table 1. The difference between traditional monitoring system and wearable biosensors in not statistically significant as shown in Figure 1; therefore the devices tested in this study show a satisfying level of reliability in monitoring cardiac rate, pulse oximetry, QT interval, QRS complexes, and onset of arrhythmic events. However, alerts produced by arrhythmias different from atrial fibrillation are not completely reliable; moreover, the software and the diagnostic algorithm need to be optimized for motion artefacts. For these reasons, results need to be reproduced on a large cohort of patients.

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Perspectives of physicians on medical acupuncture in Lebanon: a preliminary study

Acupuncture in Medicine ◽

10.1177/0964528420968835 ◽

2020 ◽

pp. 096452842096883

Author(s):

Fadila Bassem Naji ◽

Kamal Wahab ◽

Ghassan Hamadeh ◽

Sani Hlais

Keyword(s):

Integrative Medicine ◽

Online Survey ◽

Response Rate ◽

Mechanisms Of Action ◽

Medical Curricula ◽

Chinese Acupuncture ◽

The Future ◽

Preliminary Study ◽

Medical Acupuncture ◽

The Difference

Objectives: There are no regulations governing the practice of acupuncture in Lebanon as it is not yet registered as a profession. To our knowledge, no studies have ever been conducted in Lebanon regarding the practice of acupuncture. The purpose of this preliminary study was to explore the knowledge of Lebanese physicians about acupuncture, with the intent of conducting larger scale studies and developing strategies aimed at refining this knowledge in the future, and the ultimate goal of setting guidelines for acupuncture practice in Lebanon. Methods: An online survey looking into physicians’ knowledge of acupuncture, its mechanisms of action, effectiveness, indications and safety, and physicians’ understanding of its concepts, was circulated to 4651 physicians registered in the Lebanese orders of physicians. Results: One hundred forty-nine physicians (3.2%) completed the survey. Most study respondents stated that they were unaware of the difference between traditional Chinese acupuncture (TCA) and Western medical acupuncture (WMA). Overall, 30% of respondents had personally used and/or referred patients for acupuncture. Physicians who had personally tried acupuncture were more likely to refer patients for acupuncture (p < 0.001). Those who know the difference between WMA and TCA were more likely to have tried or referred for acupuncture (p = 0.004). 72% believed that acupuncture and other integrative medicine modules should be introduced in medical curricula in Lebanon. Conclusion: Interest in acupuncture among physicians in Lebanon appears to be limited, based on the low response rate. Among respondents, physicians who had tried or referred patients for acupuncture appeared to be more well informed about different acupuncture styles.

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Wideband Absorbance in Ears with Retraction Pockets and Cholesteatomas: A Preliminary Study

Journal of the American Academy of Audiology ◽

10.1055/s-0040-1719130 ◽

2021 ◽

Author(s):

Sreedevi Aithal ◽

Venkatesh Aithal ◽

Joseph Kei ◽

Shane Anderson

Keyword(s):

Prospective Study ◽

Roc Curve ◽

Operating Characteristic ◽

Peak Pressure ◽

Clinical Sample ◽

Ambient Pressure ◽

Control Group ◽

Retraction Pockets ◽

Preliminary Study ◽

The Difference

Abstract Objectives The objective of this study was to describe wideband absorbance (WBA) findings in patients with cholesteatomas and retraction pockets (RPs). Design In this prospective study, tympanometry, audiometry, and wideband tympanometry (WBT) were performed on 27 ears with an RP (eight with epitympanic RP and 19 ears with mesotympanic RP), 39 ears with a cholesteatoma (23 ears with epitympanic and 16 ears with mesotympanic cholesteatomas [MCs]), and 49 healthy ears serving as controls. Results Mean WBA at ambient pressure (WBAamb) of both experimental groups was reduced significantly between 0.8 and 5 kHz relative to the control group. The difference between mean WBAamb and mean WBA at tympanometric peak pressure (WBATPP) was greater for the RP (0.12–0.16 between 0.5 and 1.5 kHz) than for the cholesteatoma group (0.03–0.11 between 0.6 and 3 kHz). Mean WBAamb of both epitympanic RP (ERP) and epitympanic cholesteatoma (EC) subgroups was significantly lower than that of the control group. Mean WBATPP of the ERP subgroup attained normal levels as per the control group, while mean WBATPP of EC subgroup was significantly lower than that of the control group at 0.8 to 1.5 kHz and 4 to 5 kHz. In contrast, both mesotympanic RP and MC subgroups demonstrated similar mean WBAamb and WBATPP values. No significant differences in WBAamb and WBATPP results between the RP and cholesteatomas groups were observed. Receiver operating characteristic (ROC) analyses indicated that the area under the ROC curve for distinguishing between the RP and cholesteatomas groups ranged from 0.44 to 0.60, indicating low accuracy in separating the two groups. Conclusion While it is not possible to distinguish between the RP and cholesteatomas groups based on the WBAamb and WBATPP results, it is potentially feasible to differentiate between the EC and ERP conditions. Further study using a large clinical sample is recommended to determine the sensitivity and specificity of the WBA test to identify the EC and ERP conditions.

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Preliminary Study of the Use of Root with Sedline® EEG Monitoring for Assessment of Anesthesia Depth in 6 Horses

Applied Sciences ◽

10.3390/app10031050 ◽

2020 ◽

Vol 10 (3) ◽

pp. 1050

Author(s):

Olga Drewnowska ◽

Bernard Turek ◽

Barbara Lisowska ◽

Charles E. Short

Keyword(s):

Brain Activity ◽

Muscle Relaxation ◽

Eeg Monitoring ◽

Careful Monitoring ◽

Spectral Edge Frequency ◽

Non Invasive ◽

Anesthesia Monitoring ◽

Physiologic Parameters ◽

Preliminary Study ◽

Anesthesia Depth

Management of equine anesthesia monitoring is still a challenge. Careful monitoring to provide guidelines for anesthesia depth assessment currently relies upon eye signs, cardiopulmonary responses, and the level of muscle relaxation. Electroencephalography, as a non-invasive brain activity monitor, may be used to complement the routinely monitored physiologic parameters. Six horses, undergoing various surgical procedures and anesthesia protocols, were monitored with the use of a Root with Sedline EEG monitor and a routine monitor of life parameters. The life parameters were compared to the changes on the EEG density spectral array observed live during anesthesia. During all procedures the level of awareness was monitored using the EEG, with higher frequency and power of waves indicating a higher level of awareness. It was evident from this that there were variations according to the type of procedure and the anesthetic protocol. Cerebral activity was elevated during painful moments of the surgery and recovery, requiring adjustments in anesthetic concentrations. Evaluation of changes in the spectral edge frequency (SEF) could show the periods when the patient is stabilized. EEG monitoring has the potential to be used in clinical anesthesiology of horses. It was shown that this system may be used in horses under general anesthesia but is currently less effective in a standing horse for diagnostic or minor procedures.

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Validation of cerebral arteriovenous malformation hemodynamics assessed by DSA using quantitative magnetic resonance angiography: preliminary study

Journal of NeuroInterventional Surgery ◽

10.1136/neurintsurg-2017-012991 ◽

2017 ◽

Vol 10 (2) ◽

pp. 156-161 ◽

Cited By ~ 19

Author(s):

Sophia F Shakur ◽

Denise Brunozzi ◽

Ahmed E Hussein ◽

Andreas Linninger ◽

Chih-Yang Hsu ◽

...

Keyword(s):

Magnetic Resonance ◽

Magnetic Resonance Angiography ◽

Transit Time ◽

Internal Carotid ◽

Flow Measurements ◽

Quantitative Magnetic Resonance ◽

Transit Times ◽

Before And After ◽

Preliminary Study ◽

The Difference

BackgroundThe hemodynamic evaluation of cerebral arteriovenous malformations (AVMs) using DSA has not been validated against true flow measurements.ObjectiveTo validate AVM hemodynamics assessed by DSA using quantitative magnetic resonance angiography (QMRA).Materials and methodsPatients seen at our institution between 2007 and 2016 with a supratentorial AVM and DSA and QMRA obtained before any treatment were retrospectively reviewed. DSA assessment of AVM flow comprised AVM arterial-to-venous time (A-Vt) and iFlow transit time. A-Vt was defined as the difference between peak contrast intensity in the cavernous internal carotid artery and peak contrast intensity in the draining vein. iFlow transit times were determined using syngo iFlow software. A-Vt and iFlow transit times were correlated with total AVM flow measured using QMRA and AVM angioarchitectural and clinical features.Results33 patients (mean age 33 years) were included. Nine patients presented with hemorrhage. Mean AVM volume was 9.8 mL (range 0.3–57.7 mL). Both A-Vt (r=−0.47, p=0.01) and iFlow (r=−0.44, p=0.01) correlated significantly with total AVM flow. iFlow transit time was significantly shorter in patients who presented with seizure but A-Vt and iFlow did not vary with other AVM angioarchitectural features such as venous stenosis or hemorrhagic presentation.ConclusionsA-Vt and iFlow transit times on DSA correlate with cerebral AVM flow measured using QMRA. Thus, these parameters may be used to indirectly estimate AVM flow before and after embolization during angiography in real time.

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Non-invasive diagnosis of early pulmonary disease in PECAM-deficient mice using infrared pulse oximetry

Experimental and Molecular Pathology ◽

10.1016/j.yexmp.2009.07.008 ◽

2009 ◽

Vol 87 (2) ◽

pp. 152-158 ◽

Cited By ~ 8

Author(s):

Merideth A. Early ◽

Marta Lishnevsky ◽

John M. Gilchrist ◽

David M. Higgins ◽

Ian M. Orme ◽

...

Keyword(s):

Pulse Oximetry ◽

Pulmonary Disease ◽

Non Invasive ◽

Deficient Mice

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Flow cytometry of human semen: a preliminary study of a non-invasive method for the detection of spermatogenetic defects

Human Reproduction ◽

10.1093/humrep/dei247 ◽

2005 ◽

Vol 20 (12) ◽

pp. 3469-3475 ◽

Cited By ~ 18

Author(s):

N. Levek-Motola ◽

Y. Soffer ◽

L. Shochat ◽

A. Raziel ◽

L.M. Lewin ◽

...

Keyword(s):

Flow Cytometry ◽

Human Semen ◽

Non Invasive ◽

Invasive Method ◽

Preliminary Study

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Effect of a static magnetic field onEscherichia coliadhesion and orientation

Canadian Journal of Microbiology ◽

10.1139/cjm-2015-0839 ◽

2016 ◽

Vol 62 (11) ◽

pp. 944-952 ◽

Cited By ~ 1

Author(s):

Lotfi Mhamdi ◽

Nejib Mhamdi ◽

Naceur Mhamdi ◽

Philippe Lejeune ◽

Nicole Jaffrezic ◽

...

Keyword(s):

Magnetic Field ◽

Tin Oxide ◽

Indium Tin Oxide ◽

Bacterial Adhesion ◽

Parallel Magnetic Field ◽

Field Orientation ◽

Static Magnetic Fields ◽

Preliminary Study ◽

The Difference ◽

The Magnetic Field

This preliminary study focused on the effect of exposure to 0.5 T static magnetic fields on Escherichia coli adhesion and orientation. We investigated the difference in bacterial adhesion on the surface of glass and indium tin oxide-coated glass when exposed to a magnetic field either perpendicular or parallel to the adhesion surface (vectors of magnetic induction are perpendicular or parallel to the adhesion surface, respectively). Control cultures were simultaneously grown under identical conditions but without exposure to the magnetic field. We observed a decrease in cell adhesion after exposure to the magnetic field. Orientation of bacteria cells was affected after exposure to a parallel magnetic field. On the other hand, no effect on the orientation of bacteria cells was observed after exposure to a perpendicular magnetic field.

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Understanding the use of pulse oximetry in COVID-19 disease

Practice Nursing ◽

10.12968/pnur.2021.32.8.312 ◽

2021 ◽

Vol 32 (8) ◽

pp. 312-316

Author(s):

Paul Silverston

Keyword(s):

Oxygen Saturation ◽

Pulse Oximetry ◽

Respiratory Symptoms ◽

Disease Process ◽

Clinical Findings ◽

The Other ◽

Know How ◽

Non Invasive ◽

Pulse Oximeters ◽

The Way

The pandemic has led to an increase in the use of pulse oximetry to assess and manage patients with COVID-19 disease. Paul Silverston explains the principles of pulse oximetry and the factors that can affect the reliability and accuracy of readings Pulse oximetry is performed to detect and quantify the degree of hypoxia in patients with respiratory symptoms and illnesses, including patients with COVID-19 disease. Pulse oximeters are non-invasive, simple to use and inexpensive, but it is important to know how to interpret the readings in the context of the patient's symptoms and the other clinical findings. In COVID-19 disease, very small differences in the oxygen saturation reading result in significant differences in the way that the patient is managed, so it is important to be aware of the factors that can affect these readings. It is also important to appreciate that a low reading in a patient with suspected or confirmed COVID-19 disease may be the result of another disease process.

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Capnography and Pulse Oximetry Improve Fast Track Extubation in Patients Undergoing Coronary Artery Bypass Graft Surgery: A Randomized Clinical Trial

10.21203/rs.3.rs-496561/v1 ◽

2021 ◽

Author(s):

Seyed Tayeb Moradian ◽

Fatemah Beitollahi ◽

Mohammad Saeid Ghiasi ◽

Amir vahedian-azimi

Keyword(s):

Clinical Trial ◽

Pulse Oximetry ◽

Fast Track ◽

Artery Bypass ◽

Bypass Graft ◽

Intervention Group ◽

Control Group ◽

Artery Bypass Graft ◽

Cabg Surgery ◽

Non Invasive

Abstract Background Use of capnography as a non-invasive method during the weaning process for fast track extubation (FTE) is controversial. We conducted the present study to determine whether pulse oximetry and capnography could be utilized as alternatives to arterial blood gas (ABG) measurements in patients under mechanical ventilation (MV) following coronary artery bypass graft (CABG) surgery. Methods In this randomized clinical trial, 70 patients, who were candidates for CABG surgery, were randomly assigned into two equal groups (n = 35); the intervention group and the control group. In the intervention group, the ventilator management and weaning from MV was done using Etco2 from capnography and SpO2 from pulse oximetry. Meanwhile, in the control group, weaning was done based on ABG analysis. The length of intensive care unit (ICU) stay, time to extubation, number of manual ventilator setting changes, and alarms were compared between the groups. Results The end-tidal carbon dioxide (ETCO2) levels in the intervention group were completely similar to the partial pressure of carbon dioxide (PaCo2) in the control group (39.5 ± 3.1 vs. 39.4 ± 4.32, P > 0.05). The mean extubation times were significantly shorter in the intervention group compared to those in the control patients (212.2 ± 80.6 vs. 342.7 ± 110.7, P < 0.001). Moreover, the number of changes in the manual ventilator setting and the number of alarms were lower in the intervention group (P < 0.05). However, the differences in the length of stay in ICU between the two groups were not significant (P = 0.219). Conclusion According to our results, the use of non-invasive monitors, including capnography and pulse oximetry, is emphasized in order to utilize FTE after CABG surgery. Furthermore, it is a safe and valuable monitor that could be a good alternative for ABG in this population. Nevertheless, further studies with larger sample sizes and on different disease states and populations are required to assess the accuracy of our findings. Trial registration: IRCT, IRCT201701016778N6, Registered 3 March 2017, https://www.irct.ir/trial/7192

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