scholarly journals Clinical observation of a patient with hemangiomatosis involving skin, subcutaneous tissue, lung, stomach, intestinal, liver, kidney, spine

2021 ◽  
pp. 96-106
Author(s):  
V. V. Voytsekhovskiy ◽  
O. V. Litvak ◽  
V. A. Samokhvalov ◽  
O. V. Gaidarova ◽  
E. D. Naumenko ◽  
...  
Keyword(s):  
High Risk ◽  
Clinical Observation ◽  
Artificial Ventilation ◽  
Subcutaneous Tissue ◽  
Vascular Tumors ◽  
Internal Organs ◽  
Intravenous Anesthesia ◽  
Risk Of Rupture ◽  
Perinatal Center ◽  
Ventilation Of The Lungs

Aim. The work demonstrates a clinical case of an extremely rare pathology ‒ hemangiomatosis with damage to the skin, subcutaneous tissue, lungs, stomach, intestinal, liver, kidneys, and spine. Results. Patient L., born in 1994 with multiple hemangiomas. No heredity was observed for vascular tumors. In childhood, several large hemangiomas had to be surgically removed. She resorted to the Amur Regional Perinatal Center about her first pregnancy. There was a high risk of hemorrhagic complications due to damage to internal organs, primarily the lungs. Since there were multiple lesions of the vertebrae, it was decided not to use neuraxial methods of anesthesia. Total intravenous anesthesia and artificial ventilation of the lungs under the control of bronchoscopy were chosen by the method of anesthesia. Hemangiomatosis with lesions of internal organs was the indication for a Cesarean section. The operation took place without complications. The child was born healthy. Conclusion. In most cases, cosmetic defects are a significant problem of hemangiomatosis. However, in a number of situations, for example during pregnancy, there is a high risk of rupture of hemangiomas and the development of bleeding. In this case, the choice of the method of delivery and anesthesia depends on the location of the hemangiomas.

scholarly journals A rare case of pseudoaneurysm at the site of untreated coarctation of the aorta in an adult patient

2020 ◽  
Author(s):  
Takuma Mikami ◽  
Takeshi Kamada ◽  
Hiroki Uchiyama ◽  
Yosuke Kuroda ◽  
Ryo Harada ◽  
...  
Keyword(s):  
High Risk ◽  
Aortic Aneurysm ◽  
Aortic Coarctation ◽  
Poor Prognosis ◽  
Rare Case ◽  
Surgical Repair ◽  
Coarctation Of The Aorta ◽  
Pathological Findings ◽  
Open Surgical Repair ◽  
Risk Of Rupture

Abstract Here we report a rare case of pseudoaneurysm at the site of aortic coarctation. Aortic coarctation and a saccular aortic aneurysm protruding from the site of this coarctation were detected in a 50-year-old woman. Owing to the shape of the aneurysm and high risk of rupture, an open surgical repair was performed. The pathological findings of the removed aneurysm revealed a pseudoaneurysm consisting of only a thin adventitial wall. Adult uncorrected aortic coarctation has a poor prognosis. One of its causes may be the formation of such a pseudoaneurysm.

Effects of local cooling or heating in deeply hypothermic rats

1960 ◽  
Vol 15 (3) ◽  
pp. 435-439 ◽  
Author(s):  
D. P. Orchard ◽  
E. F. Adolph
Keyword(s):  
Blood Flow ◽  
Core Temperature ◽  
Oxygen Delivery ◽  
Spontaneous Breathing ◽  
Artificial Ventilation ◽  
Vena Cava ◽  
Local Cooling ◽  
The Mean ◽  
Ventilation Of The Lungs ◽  
The Brain

Rats were cooled to 17°C core temperature, and then either the head or the chest was further cooled by 5° – 10°. Thermocouples in the hypothalamus and in the vena cava recorded the differences of temperature; electrocardiograms and breathing were observed. Breathing could cease reversibly when the head was cooled and also after a period of gasping whenever the heart was much cooler than the head. Artificial ventilation of the lungs with air did not modify the result of restricted blood flow. Whenever the brain was cooler than the heart, however, artificial ventilation with air could replace spontaneous breathing; the blood flow was then usually adequate. Artificial ventilation with nitrogen reduced the time within which recovery was possible. In general the warmest tissue (head or chest) determined the time of endurance without adequate delivery of oxygen from lungs and blood. Any local cooling failed to increase the rat's endurance of oxygen lack. The results are interpreted to mean that failures to survive below 14°C for 1 hour are due to inadequate oxygen delivery. However, even oxygen delivery believed to be adequate did not allow indefinite survival; 2 hours remained the mean tolerance time below 14°C. Submitted on November 23, 1959

Primary venous aneurysms: A 20-year retrospective analysis

Vascular ◽  
2020 ◽  
Vol 28 (5) ◽  
pp. 577-582
Author(s):  
Samantha Gabriel ◽  
Naomi Eisenberg ◽  
Denise Kim ◽  
Arash Jaberi ◽  
Graham Roche-Nagle
Keyword(s):  
High Risk ◽  
Symptom Management ◽  
Inferior Vena ◽  
Surgical Repair ◽  
Vena Cava ◽  
Duplex Ultrasound ◽  
Time Frame ◽  
Risk Of Rupture ◽  
History Of ◽  
Medical Histories

Objective Primary venous aneurysms are unusual vascular occurrences. Our aim is to document our institution’s experience with this pathology; describing frequency, diagnosis, outcomes and medical histories of patients with primary venous aneurysms within a 20-year time frame. Methods A retrospective study at our institution using its radiology database was conducted. Results were isolated to primary venous aneurysms diagnosed between 1997 and 2017. Basic demographics and medical history were collected. Results We identified 32 patients with primary venous aneurysms. Eighteen were male and 14 were female. The average age of presentation was 54 years old, with a range of 17–86. None of these patients reported a family history of aneurysmal disease. The majority were incidental. Of these aneurysms, 3 were of the head and neck, 1 was contained in the thorax, 17 were intra-abdominal and 11 were peripheral. Diagnosis was made by computed tomography, duplex ultrasound, or magnetic resonance imaging. Conservative management was most frequently employed, but four patients underwent surgical repair. Three aneurysms required operation for symptom management (external jugular, subclavian, inferior vena cava), whereas one aneurysm of the popliteal vein was prophylactically managed, given the high risk for pulmonary embolism. Conclusions Primary venous aneurysms present infrequently. Despite their rarity, primary venous aneurysms have been reported to occur throughout the venous system. The majority of primary venous aneurysms in this series were found incidentally and can present both symptomatically or asymptomatically. The findings of our 20-year experience were consistent with the existing literature. Because the risk of rupture is negligible, the indications for surgical management remain for cosmesis, symptom management or high risk of thromboembolic events.

Investigating the Effect of Intraluminal Thrombus in Abdominal Aortic Aneurysm by Computational and Experimental Methods

2009 ◽  
Author(s):  
Florentina Ene ◽  
Carine Gachon ◽  
Patrick Delassus ◽  
Liam Morris
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
High Risk ◽  
Aortic Aneurysm ◽  
Abdominal Aorta ◽  
Experimental Methods ◽  
Infrarenal Aorta ◽  
Intraluminal Thrombus ◽  
Abdominal Aortic ◽  
Risk Of Rupture

Abdominal aortic aneurysm (AAA) represents an abnormal dilatation and weakening of the abdominal aorta with high risk of rupture. Most aneurysms of the infrarenal aorta possess an asymmetrical fusiform morphology.

scholarly journals Canine Bite-Mark Evidence in Veterinary Necropsy: Case Studies Featuring the Bite-Mark Examination

2019 ◽  
Vol 76 (1) ◽  
pp. 93
Author(s):  
Adrian Florin GAL ◽  
Roxana CORA ◽  
Flaviu TᾸBᾸRAN ◽  
Andras NAGY ◽  
Cornel CǍTOI
Keyword(s):  
Veterinary Medicine ◽  
Subcutaneous Tissue ◽  
Veterinary Science ◽  
Internal Organs ◽  
Cutaneous Wounds ◽  
Bite Marks ◽  
Bite Mark ◽  
Veterinary Pathology ◽  
Tissue Rupture ◽  
Bite Wounds

Forensic veterinary medicine tends to gain increasing importance in veterinary pathology, the number of such cases being still limited. The paper describes cases with multiple cutaneous wounds, with emphasis on bite-mark analysis. The material was represented by corpses (deer and dogs) brought by local authorities to Faculty of Veterinary Medicine Cluj-Napoca (Romania), along with preliminary reports issued by the competent organs. A complete medicolegal survey was done. The cases analyzed by us displayed numerous usually symmetrical (opposed) wounds, with angular margins and elongated aspect (somehow specific to bite wounds). All cases assessed presented laceration of the skin from the subcutaneous tissue, rupture of muscle and (in some cases) perforation of internal organs. The features of the bite-marks described were typical for carnivores. Depending on the species involved, the topography of lesions varied. In deer, the ventrolateral area of the neck and the lumbar/dorsal region were more commonly affected. The distribution suggests the hunting instinct of carnivores by trying to induce suffocation of the prey. In the analyzed dog corpses, the most affected areas were the auricular, limbs, sternal region, abdominal region. Investigation of bite-marks is an evolving field of forensic veterinary science and remains a provocation for veterinary pathologists.

scholarly journals Severe Anaphylactic Reaction to Diclofenac during Intravenous Anesthesia for In Vitro Fertilization

2019 ◽  
Vol 2019 ◽  
pp. 1-3
Author(s):  
Nebojsa Videnovic ◽  
Nebojsa Markovic ◽  
Jovan Mladenovic ◽  
Marija Jovic ◽  
Rasa Mladenovic ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Anaphylactic Reaction ◽  
Clinical Observation ◽  
Clinical Manifestations ◽  
Time Interval ◽  
Intravenous Anesthesia ◽  
Vitro Fertilization ◽  
Other Substances ◽  
Severe Anaphylactic Reaction

We present a case of a severe anaphylactic reaction to diclofenac, administered as an intravenous infusion in a 45-year-old patient, during intravenous anesthesia for in vitro fertilization. During the preoperative clinical examination and obtaining of anamnestic data, the patient denied symptoms of allergies to medicines and other substances. The dominant clinical manifestations of anaphylactic reaction were: hypotension, tachycardia, angioedema, bronchospasm, and delayed awakening following anesthesia. No visible changes in the appearance of the skin, such as erythema or urticaria have been observed. Proper clinical observation and adequate intraoperative monitoring led to rapid diagnosis and significantly reduced the time interval from the onset of anaphylaxis to the beginning of treatment and reanimation procedures.

Adjuvant radiotherapy after lymphadenectomy in melanoma patients: Final results of an intergroup randomized trial (ANZMTG 0.1.02/TROG 02.01).

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. 9001-9001 ◽  
Author(s):  
Michael A. Henderson ◽  
Bryan Burmeister ◽  
Jill Ainslie ◽  
Richard Fisher ◽  
Julianna Di Iulio ◽  
...  
Keyword(s):  
High Risk ◽  
Randomized Trial ◽  
Adjuvant Radiotherapy ◽  
Subcutaneous Tissue ◽  
Final Report ◽  
Metastatic Node ◽  
Logrank Test ◽  
Long Term Treatment ◽  
Melanoma Patients

9001 Background: The role of adjuvant radiotherapy following lymphadenectomy in melanoma patients identified as at high risk for further recurrence has been controversial. This final report of a multicenter randomized trial updates survival and lymph node field (LNF) control, and reports long term treatment toxicity, lymphedema and quality of life (QOL) (Lancet Oncol 2012;13:589-97). Methods: Patients at high risk of LNF relapse (≥1 parotid, ≥2 cervical or axillary or ≥3 groin positive nodes; or extra-nodal spread of tumour; or minimum metastatic node diameter of 3cm (neck or axilla) or 4cm (groin)) received adjuvant radiotherapy (ART) (48Gy in 20 fractions) or observation (OBS). LNF relapse, as a 1st relapse, was the primary endpoint; morbidity, QOL, patterns of relapse, disease free and overall survival were secondary endpoints. A target sample size of 250 enabled detection of a difference in 3 year relapse rates of 30% and 15% to be detected (2-sided logrank test, power of 80%). Results: 250 patients from 16 centres were randomized from Mar 02 to Sept 07 (123 ART; 127 OBS) with 217 fully eligible (109 ART, 108 OBS). Mean follow-up 73 months (range 21–116). LNF recurrence was reduced in the ART arm (HR=0.52 (0.31- 0.88) p=0.023) but there was no difference in survival (HR=1.13 (0.82 – 1.55) p =0.21). QOL was assessed by comparison of area under the curve from baseline to 5 years (or recurrence) with the FACT-G tool using both total score and the 4 major domains (physical, social, emotional and functional wellbeing), no difference. Regional symptoms (standardised questionnaire) were higher in the ART arm (p=0.035). Limb volumes were higher in the ART arm (leg 7.3% difference p=0.014, arm 3.4% p=0.25). Grade 2-4 RT toxicity was common for head + neck: skin (33%); axilla: skin (44%), subcutaneous tissue (41%); Groin: skin (46%), subcutaneous tissue (67%), other (38%). Conclusions: RT reduced the risk of LNF relapse by 52% but there was no impact on survival. In the ART arm loco-regional symptoms were worse, limb volumes were somewhat increased and Grade 2 - 4 long term RT toxicity was relatively common. However QOL as assessed by a validated tool (FACT-G) was similar in both groups. Clinical trial information: NCT00287196.

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