Oral Misoprostol for 48 hours Versus a Supra Cervical Foley Catheter for 48 Hours for Induction of Labour in Post Dated Pregnancies: A Randomized Control Trial

Background: The present study aims to compare the results of EASI followed by oral misoprostol and oral misoprostol alone for induction of labour in pregnancies of more than 28 weeks with intrauterine foetal death. Methods: The present observational and prospective study is an attempt to compare the efficacy of extra-amniotic saline instillation with Foley catheter prior to oral misoprostol and oral misoprostol alone in induction of labour of pregnancies more than 28 weeks with intrauterine fetal death. Results: Most of the cases delivered vaginally in both study groups. The mean induction delivery time in group I was higher than group II and the results were statistically significant on comparing both groups. In group I, 78% cases were delivered within 24 hours whereas in group II 96% cases delivered within 24 hours of induction. There was no significant difference in the mean number of required misoprostol in both groups (p>0.05). Need of supplementation with oxytocin was more in group I as compared to group II and the p value is significant (p<0.01). Mean birth weight in group I was 2.25±0.75 kg and in group II was 2.27±0.77 kg. Maximum number of babies had birth weight between 1.52-2.50 kg with 44% in group I and 40% in group II (p>0.05). Only 4 cases had uterine tachysystole and only 1case had postpartum pyrexia. Very few complications were recorded in both the study groups (p>0.05). Conclusion: We concluded that oral misoprostol tablet alone is more effective at inducing and setting up the active labour in pregnancies of >28 weeks with intrauterine foetal death than EASI followed by oral misoprostol. It is inexpensive, has a long shelf life, can be easily stored at room temperature and patient remains ambulatory after induction with oral misoprostol. Oral misoprostol alone seems to have an edge over extra-amniotic saline instillation followed by oral misoprostol in all aspects. Keywords: Misoprostol, Extra-amniotic saline, Induction of labour.

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Erratum To: Induction of labour with a Foley catheter or oral misoprostol at term: the PROBAAT-II study, a multicentre randomised controlled trial

BMC Pregnancy and Childbirth ◽

10.1186/1471-2393-13-183 ◽

2013 ◽

Vol 13 (1) ◽

Cited By ~ 1

Author(s):

Mieke LG ten Eikelder ◽

Femke Neervoort ◽

Katrien Oude Rengerink ◽

Gert J van Baaren ◽

Marta Jozwiak ◽

...

Keyword(s):

Randomised Controlled Trial ◽

Controlled Trial ◽

Foley Catheter ◽

Induction Of Labour ◽

Oral Misoprostol ◽

Randomised Controlled

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Induction of labor using Foley catheter with weight attached vs without weight attached: A randomized control trial

International Journal of Gynecology & Obstetrics ◽

10.1002/ijgo.13729 ◽

2021 ◽

Author(s):

Anne George Cherian ◽

Tobey Ann Marcus ◽

Tunny Sebastian ◽

Swathi Rathore ◽

Jiji Elizabeth Mathews

Keyword(s):

Randomized Control Trial ◽

Foley Catheter ◽

Induction Of Labor ◽

Randomized Control

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The Induction with Foley OR Misoprostol (INFORM) Study dataset. A dataset of 602 women with hypertensive disease in pregnancy, in India, randomised to either Foley catheter or oral misoprostol for induction of labour

BMC Research Notes ◽

10.1186/s13104-021-05772-9 ◽

2021 ◽

Vol 14 (1) ◽

Author(s):

Shuchita Mundle ◽

Hillary Bracken ◽

Vaishali Khedikar ◽

Jayashree Mulik ◽

Brian Faragher ◽

...

Keyword(s):

Low Income ◽

Foley Catheter ◽

Mode Of Delivery ◽

Randomised Trial ◽

Induction Of Labour ◽

Cervical Ripening ◽

Labour Induction ◽

Mortality And Morbidity ◽

Oral Misoprostol ◽

In Pregnancy

Abstract Objectives Induction of labour (IOL), or starting labour artificially, can be a lifesaving intervention for pregnant women and their babies, and rates are rising significantly globally. As rates increase, it becomes increasingly important to fully evaluate all available data, especially that from low income settings where the potential benefits and harms are greater. The goal of this paper is to describe the datasets collected as part of the Induction with Foley OR Misoprostol (INFORM) Study, a randomised trial comparing two of the recommended methods of cervical ripening for labour induction, oral misoprostol and Foley catheter, in women being induced for hypertension in pregnancy, at two sites in India during 2013–15. Data description This dataset includes comprehensive data on 602 women who underwent IOL for hypertensive disorders in pregnancy. Women were randomly assigned to cervical ripening with oral misoprostol or a transcervical Foley catheter in two government hospitals in India. The main dataset has 367 variables including monitoring during the induction of labour, medications administered, timing and mode of delivery, measures of neonatal morbidity and mortality, maternal mortality and morbidity, maternal satisfaction and health economic data. The dataset is anonymised and available on ReShare.

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