Aldosterone Antagonism in the Pharmacological Management of Chronic Heart Failure

2007 ◽  
pp. 82-103
Author(s):  
Biykem Bozkurt
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Pharmacological Management ◽  
Aldosterone Antagonism

Heart failure

2010 ◽  
pp. 3-28
Author(s):  
Juan Carlos Kaski
Keyword(s):  
Heart Failure ◽  
Clinical Trials ◽  
Chronic Heart Failure ◽  
Systolic Function ◽  
Diastolic Heart Failure ◽  
Systolic Heart Failure ◽  
The Body ◽  
Pharmacological Management ◽  
Reduced Ejection Fraction ◽  
Structural Abnormalities

Introduction 4 Chronic heart failure with reduced LVEF (systolic heart failure) 6 Pharmacological management of chronic heart failure 8 Non-pharmacological management of chronic heart failure 18 Chronic heart failure with preserved LVEF (diastolic heart failure) 20 Acute heart failure 22 Clinical trials 26 Heart failure (HF) is a complex condition that results from cardiac functional and/or structural abnormalities that affect the ability of the heart to pump blood, and is often defined as the inability of the heart to adequately perfuse the organs of the body. Symptoms of HF vary depending on several factors but the most common manifestations of HF are dyspnoea and fatigue. Of importance, HF is not necessarily associated with a reduced ejection fraction (EF) (systolic HF), as up to 50% of cases occur in the presence of a preserved systolic function (diastolic dysfunction)....

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