Prevalence and factors associated with osteoporosis and bone mineral density testing in psoriatic arthritis

2020 ◽  
Author(s):  
Timothy S.H. Kwok ◽  
Mitchell Sutton ◽  
Justine Yang Ye ◽  
Daniel Pereira ◽  
Vinod Chandran ◽  
...  
2009 ◽  
Vol 18 (7) ◽  
pp. 989-994 ◽  
Author(s):  
Laura Davisson ◽  
Mary Warden ◽  
Shanthi Manivannan ◽  
Maria Kolar ◽  
Christine Kincaid ◽  
...  

2014 ◽  
Vol 10 (2) ◽  
pp. 89-93 ◽  
Author(s):  
Noemi Busquets ◽  
Carmen Gómez Vaquero ◽  
Jesús Rodríguez Moreno ◽  
Daniel Roig Vilaseca ◽  
Javier Narváez ◽  
...  

Medical Care ◽  
2014 ◽  
Vol 52 (8) ◽  
pp. 743-750 ◽  
Author(s):  
Amy H. Warriner ◽  
Ryan C. Outman ◽  
Adrianne C. Feldstein ◽  
Douglas W. Roblin ◽  
Jeroan J. Allison ◽  
...  

Bone ◽  
2010 ◽  
Vol 46 (4) ◽  
pp. 1058-1062 ◽  
Author(s):  
Hannes Hrafnkelsson ◽  
Gunnar Sigrudsson ◽  
Kristjan Th. Magnusson ◽  
Erlingur Johannsson ◽  
Emil L. Sigurdsson

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Mahira Hamdy El Sayed ◽  
Rania Mahmoud El Husseiny ◽  
Omar Adnan Hoom Al Saadi

Abstract Background Psoriasis is considered as a systemic disease since it is an inflammatory skin disorder associated with increased level of many inflammatory cytokines, which can result in many comorbidities. It was hypothesized that there is an association between psoriasis and osteoporosis and many studies investigated this association, but the majority of them focused on the association between psoriatic arthritis and osteoporosis, while this study excluded psoriatic arthritis and investigated the association between psoriasis of different clinical varieties and osteoporosis. Objective to assess the associated relationship between psoriasis and osteoporosis in psoriatic patients of different clinical varieties, by measuring the prevalence of osteoporosis in a sample of these patients. Subjects and methods Our cross-sectional study included 42 psoriatic male and female patients with non specific ages, 48% of them were males (20 patients) and 52% of them were females (22 patients), and it excluded any patients with endocrinal disorders, chronic renal failure, liver cell failure, other chronic inflammatory disoredres, malabsorption, history of alcohol misuse, history of intake of steroids for longer than 6 months, pregnant women and psoriatic arthritis. All patients were subjected to a questionnaire for detailed history taking, complete general and dermatological examinations, evaluation of psoriasis severity by Psoriasis Area and Severity Index (PASI) score and bone mineral density (BMD) measurement using the DEXA method of the lumbar spine (L1L4) and femoral neck. Results The prevalence of osteoporosis among psoriatic patients was (9.5%), (10%) in males and (9%) in females, which was lower than the prevalence of osteoporosis in the population. While the prevalence of osteopenia was 50%, (45%) in males and (54.5%) in females, which was higher than the prevalence of osteopenia in the population. Additionally this study showed a statistically significant negative correlation between the age of the patients and BMD, and a highly significant positive correlation between the BMI of the patients and BMD, while there were non significant negative correlations between both (duration of psoriasis and PASI score) and BMD, and no significant correlations between clinical variants of psoriasis and BMD. Conclusion Psoriasis is associated with a decrease in the bone mineral density more in males, with higher incidence of osteopenia rather than osteoporosis. The decrease in BMD increases with increasing age, duration of psoriasis and PASI score, decreases with increasing BMI, while the clinical variants of psoriasis didn’t seem to affect the BMD of psoriatic patients.


Sign in / Sign up

Export Citation Format

Share Document