scholarly journals Tau deposition assessed by [ 18 F]MK6240 PET is associated with longitudinal decrease in grey matter density across the spectrum of Alzheimer’s disease

2020 ◽  
Vol 16 (S4) ◽  
Author(s):  
Firoza Z. Lussier ◽  
Tharick A. Pascoal ◽  
Joseph Therriault ◽  
Cécile Tissot ◽  
Mélissa Savard ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Grey Matter ◽  
Matter Density ◽  
Grey Matter Density

scholarly journals P3-481: EMOTIONAL MODULATION OF MEMORY ACROSS THE ALZHEIMER'S DISEASE SPECTRUM AND ASSOCIATION WITH GREY MATTER DENSITY

2019 ◽  
Vol 15 ◽  
pp. P1152-P1153
Author(s):  
Emilie Thomas ◽  
Joseph Therriault ◽  
Tharick A. Pascoal ◽  
Sulantha Mathotaarachchi ◽  
Melissa Savard ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Grey Matter ◽  
Matter Density ◽  
Emotional Modulation ◽  
Grey Matter Density ◽  
Disease Spectrum

scholarly journals Computational genetics analysis of grey matter density in Alzheimer’s disease

2014 ◽  
Vol 7 (1) ◽  
Author(s):  
Amanda L Zieselman ◽  
◽  
Jonathan M Fisher ◽  
Ting Hu ◽  
Peter C Andrews ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Grey Matter ◽  
Matter Density ◽  
Computational Genetics ◽  
Grey Matter Density

scholarly journals Pain sensitivity is inversely related to regional grey matter density in the brain

Pain ◽  
2014 ◽  
Vol 155 (3) ◽  
pp. 566-573 ◽  
Author(s):  
Nichole M. Emerson ◽  
Fadel Zeidan ◽  
Oleg V. Lobanov ◽  
Morten S. Hadsel ◽  
Katherine T. Martucci ◽  
...  
Keyword(s):  
Pain Sensitivity ◽  
Grey Matter ◽  
Matter Density ◽  
Grey Matter Density ◽  
The Brain

Decrease in basal ganglia grey matter density associated with atypical antipsychotic treatment in schizophrenia patients

2008 ◽  
Vol 103 (1-3) ◽  
pp. 319-321 ◽  
Author(s):  
Emmanuel Stip ◽  
Adham Mancini-Marïe ◽  
Cherine Fahim ◽  
Lahcen Ait Bentaleb ◽  
Genevieve Létourneau ◽  
...  
Keyword(s):  
Basal Ganglia ◽  
Atypical Antipsychotic ◽  
Grey Matter ◽  
Matter Density ◽  
Antipsychotic Treatment ◽  
Grey Matter Density

ELEVATED PLASMA NEUROFILAMENT LIGHT CHAIN IS ASSOCIATED WITH REDUCED GREY MATTER DENSITY IN AD AND MCI

2017 ◽  
Vol 13 (7) ◽  
pp. P1493
Author(s):  
Kacie Deters ◽  
Shannon L. Risacher ◽  
Kaj Blennow ◽  
Henrik Zetterberg ◽  
Michael Weiner ◽  
...  
Keyword(s):  
Light Chain ◽  
Grey Matter ◽  
Matter Density ◽  
Elevated Plasma ◽  
Neurofilament Light Chain ◽  
Neurofilament Light ◽  
Grey Matter Density

Voxel-based morphometry reveals an association between aerobic capacity and grey matter density in the right anterior insula

Neuroscience ◽  
2009 ◽  
Vol 163 (4) ◽  
pp. 1102-1108 ◽  
Author(s):  
J. Peters ◽  
M. Dauvermann ◽  
C. Mette ◽  
P. Platen ◽  
J. Franke ◽  
...  
Keyword(s):  
Aerobic Capacity ◽  
Grey Matter ◽  
Anterior Insula ◽  
Matter Density ◽  
Voxel Based Morphometry ◽  
Grey Matter Density ◽  
The Right

O3-03-06: Grey Matter Density in Relation to Cognitive Function

2016 ◽  
Vol 12 ◽  
pp. P288-P288
Author(s):  
Gennady V. Roshchupkin ◽  
Hazel I. Zonneveld ◽  
Hieab H.H. Adams ◽  
Meike W. Vernooij ◽  
Wiro J. Niessen ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Grey Matter ◽  
Matter Density ◽  
Grey Matter Density

Abstract 44: Associations of Atrial Fibrillation, Neuroimaging Measures of Cerebrovascular Disease and Alzheimer’S Disease-related Pathology, and Cognitive Impairment

Stroke ◽  
2015 ◽  
Vol 46 (suppl_1) ◽  
Author(s):  
Jonathan Graff-Radford ◽  
Rosebud Roberts ◽  
Malini Madhavan ◽  
Alejandro Rabinstein ◽  
Ruth Cha ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
White Matter ◽  
Cerebrovascular Disease ◽  
Regression Models ◽  
Grey Matter ◽  
White Matter Hyperintensity ◽  
Carrier Status

The objective of this study was to investigate the cross-sectional associations of atrial fibrillation with neuroimaging measures of cerebrovascular disease and Alzheimer’s disease-related pathology, and their interaction with cognitive impairment. MRI scans of non-demented individuals (n=1044) from the population-based Mayo Clinic Study of Aging were analyzed for infarctions, total grey matter, hippocampal and white matter hyperintensity volumes. A subset of 496 individuals underwent FDG and C-11 Pittsburgh compound B (PiB) PET scans. We assessed the associations of atrial fibrillation with i) categorical MRI measures (cortical and subcortical infarctions) using multivariable logistic regression models, and with ii) continuous MRI measures ( hippocampal, total grey matter, and white matter hyperintensity volumes) and FDG-PET and PiB-PET measures using multivariable linear regression models, and adjusting for confounders. Among participants who underwent MRI (median age, 77.8, 51.6% male), 13.5% had atrial fibrillation. Presence of atrial fibrillation was associated with subcortical infarctions (odds ratio [OR], 1.83; p=0.002), cortical infarctions (OR, 1.91; p=0.03), total grey matter volume (Beta [β], -.025, p<.0001) after controlling for age, education, gender, APOE e4 carrier status, coronary artery disease, diabetes, history of clinical stroke, and hypertension. However, atrial fibrillation was not associated with white matter hyperintensity volume, hippocampal volume, Alzheimer’s pattern of FDG hypometabolism or PiB uptake. There was a significant interaction of cortical infarction (p for interaction=0.004) and subcortical infarction (p for interaction =0.015) with atrial fibrillation with regards to odds of mild cognitive impairment (MCI). Using subjects with no atrial fibrillation and no infarction as the reference, the OR (95% confidence intervals [CI]) for MCI was 2.98 (1.66, 5.35;p = 0.0002) among participants with atrial fibrillation and any infarction, 0.69 (0.36, 1.33;p= 0.27) for atrial fibrillation and no infarction, and 1.50 (0.96, 2.32;p = 0.07) for no atrial fibrillation and any infarction. These data highlight that atrial fibrillation is associated with MCI in the presence of infarctions.

scholarly journals Longitudinal progression of grey matter atrophy in non-amnestic Alzheimer’s disease

Brain ◽  
2019 ◽  
Vol 142 (6) ◽  
pp. 1701-1722 ◽  
Author(s):  
Jeffrey S Phillips ◽  
Fulvio Da Re ◽  
David J Irwin ◽  
Corey T McMillan ◽  
Sanjeev N Vaishnavi ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Grey Matter ◽  
Grey Matter Atrophy
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