Dual-Responsive Boronate Crosslinked Micelles for Targeted Drug Delivery

2012 ◽  
Vol 51 (22) ◽  
pp. 5293-5295 ◽  
Author(s):  
Weixuan Chen ◽  
Yunfeng Cheng ◽  
Binghe Wang
Nanoscale ◽  
2014 ◽  
Vol 6 (13) ◽  
pp. 7635 ◽  
Author(s):  
Sheng Wang ◽  
Hanjie Wang ◽  
Zhongyun Liu ◽  
Liangliang Wang ◽  
Xiaomin Wang ◽  
...  

2015 ◽  
Vol 380 ◽  
pp. 315-320 ◽  
Author(s):  
Tejabhiram Yadavalli ◽  
Shivaraman Ramasamy ◽  
Gopalakrishnan Chandrasekaran ◽  
Isaac Michael ◽  
Helen Annal Therese ◽  
...  

2014 ◽  
Vol 6 (13) ◽  
pp. 10381-10392 ◽  
Author(s):  
Yu Shao ◽  
Changying Shi ◽  
Gaofei Xu ◽  
DanDan Guo ◽  
Juntao Luo

2012 ◽  
Vol 9 (9) ◽  
pp. 2719-2729 ◽  
Author(s):  
Remant Bahadur K. C. ◽  
Bindu Thapa ◽  
Peisheng Xu

INDIAN DRUGS ◽  
2018 ◽  
Vol 55 (11) ◽  
pp. 74-77
Author(s):  
A. S Patil ◽  
◽  
A. P. Gadad

In the present study temperature and pH responsive co-polymer chitosan-g-poly(N-isopropylacrylamide) (CS-g-PNIPAAm) was synthesized, characterized and efficiently loaded with oxaliplatin. Nanoparticles were evaluated for their physicochemical properties. The drug loaded nanoparticles showed smooth and spherical morphology with loading efficiency and drug content of about 80.7% and 48.7%, respectively. The in vitro drug release was significantly higher at tumor extracellular pH and temperature when compared to physiological pH and temperature. In conclusion, the developed nanoparticulate system is an effective dual responsive targeted drug delivery system for oxaliplatin with low toxic side effects.


RSC Advances ◽  
2016 ◽  
Vol 6 (67) ◽  
pp. 62630-62639 ◽  
Author(s):  
Seyed Jamal Tabatabaei Rezaei ◽  
Laila Sarbaz ◽  
Hassan Niknejad

Multifunctional polymeric prodrug micelles, which allow the targeted intracellular delivery and facilitated release of conjugated drugs at cytoplasm in response to an intracellular glutathione and pH level, were developed.


2018 ◽  
Vol 10 (41) ◽  
pp. 35670-35670
Author(s):  
Santanu Patra ◽  
Ekta Roy ◽  
Paramita Karfa ◽  
Sunil Kumar ◽  
Rashmi Madhuri ◽  
...  

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