TGF‐β1‐induced collagen promotes chicken ovarian follicle development via an intercellular cooperative pattern

2021 ◽  
Author(s):  
Shuo Zhou ◽  
Yanfen Ma ◽  
Jinwei Yao ◽  
An Zhao ◽  
Chukang Xie ◽  
...  
Keyword(s):  
Ovarian Follicle ◽  
Follicle Development ◽  
Ovarian Follicle Development ◽  
Tgf Β1

Morphogenesis of the silkworm egg

Development ◽  
1976 ◽  
Vol 36 (1) ◽  
pp. 13-18
Author(s):  
J. M. Legay
Keyword(s):  
Ovarian Follicle ◽  
Temporal Organization ◽  
Width Ratio ◽  
Follicle Development ◽  
Ovarian Follicle Development ◽  
Length Width ◽  
Form Stability

Ovarian follicle development, which accompanies morphogenesis of the silkworm egg has three distinct phases: spheric, ellipsoidal and flattened-ellipsoid. Transitions between phases are rapid and form-stability (characterized by length/width ratio) is preserved from the beginning of the ellipsoidal phase. The geometric stability of the follicle-oocyte-ovariole system, the polarity of the egg and the determinism in form changes reveal strikingly coordinated spatial and temporal organization.

scholarly journals An epigenetic switch repressingTet1in gonadotropes activates the reproductive axis

2017 ◽  
Vol 114 (38) ◽  
pp. 10131-10136 ◽  
Author(s):  
Yahav Yosefzon ◽  
Cfir David ◽  
Anna Tsukerman ◽  
Lilach Pnueli ◽  
Sen Qiao ◽  
...  
Keyword(s):  
Ovarian Function ◽  
Ovarian Follicle ◽  
Gene Promoter ◽  
Follicle Development ◽  
Mrna Levels ◽  
Epigenetic Switch ◽  
Ovarian Follicle Development ◽  
Reproductive Axis ◽  
Poorly Differentiated ◽  
Tet Enzymes

The TET enzymes catalyze conversion of 5-methyl cytosine (5mC) to 5-hydroxymethyl cytosine (5hmC) and play important roles during development. TET1 has been particularly well-studied in pluripotent stem cells, butTet1-KO mice are viable, and the most marked defect is abnormal ovarian follicle development, resulting in impaired fertility. We hypothesized that TET1 might play a role in the central control of reproduction by regulating expression of the gonadotropin hormones, which are responsible for follicle development and maturation and ovarian function. We find that all three TET enzymes are expressed in gonadotrope-precursor cells, butTet1mRNA levels decrease markedly with completion of cell differentiation, corresponding with an increase in expression of the luteinizing hormone gene,Lhb. We demonstrate that poorly differentiated gonadotropes express a TET1 isoform lacking the N-terminal CXXC-domain, which repressesLhbgene expression directly and does not catalyze 5hmC at the gene promoter. We show that this isoform is also expressed in other differentiated tissues, and that it is regulated by an alternative promoter whose activity is repressed by the liganded estrogen and androgen receptors, and by the hypothalamic gonadotropin-releasing hormone through activation of PKA. Its expression is also regulated by DNA methylation, including at an upstream enhancer that is protected by TET2, to allowTet1expression. The down-regulation of TET1 relieves its repression of the methylatedLhbgene promoter, which is then hydroxymethylated and activated by TET2 for full reproductive competence.

High salt intake negatively impacts ovarian follicle development

2015 ◽  
Vol 200 ◽  
pp. 79-87 ◽  
Author(s):  
Guang Wang ◽  
Cheung-Kwan Yeung ◽  
Jing-Li Zhang ◽  
Xi-Wen Hu ◽  
Yu-Xiang Ye ◽  
...  
Keyword(s):  
Salt Intake ◽  
Ovarian Follicle ◽  
High Salt ◽  
Follicle Development ◽  
Ovarian Follicle Development ◽  
High Salt Intake

Hormonal regulation of proprotein convertase subtilisin/kexin type 5 expression during ovarian follicle development in the rat

2008 ◽  
Vol 289 (1-2) ◽  
pp. 29-37 ◽  
Author(s):  
Jeong-A Bae ◽  
Hyun-Jeong Park ◽  
You-Mi Seo ◽  
Jaesook Roh ◽  
Aaron J.W. Hsueh ◽  
...  
Keyword(s):  
Hormonal Regulation ◽  
Ovarian Follicle ◽  
Follicle Development ◽  
Proprotein Convertase ◽  
Ovarian Follicle Development
Sign in / Sign up

Export Citation Format

Share Document