scholarly journals Rational Enzyme Design without Structural Knowledge: A Sequence‐Based Approach for Efficient Generation of Transglycosylases

2021 ◽  
Author(s):  
David Teze ◽  
Jiao Zhao ◽  
Mathias Wiemann ◽  
Kazi Z. G. Ara ◽  
Rossana Lupo ◽  
...  
Keyword(s):  
Structural Knowledge ◽  
Enzyme Design ◽  
Efficient Generation

scholarly journals Rational Enzyme Design Without Structural Knowledge: A Sequence-Based Approach for Efficient Generation of Glycosylation Catalysts

2020 ◽  
Author(s):  
David Teze ◽  
Zhao, Jiao ◽  
Mathias Wiemann ◽  
Zubaida Gulshan Kazi ◽  
Rossana Lupo ◽  
...  
Keyword(s):  
Amino Acids ◽  
Glycoside Hydrolase ◽  
Enzyme Engineering ◽  
Glycoside Hydrolases ◽  
Structural Knowledge ◽  
Enzyme Design ◽  
Engineering Approach ◽  
Efficient Generation ◽  
One Step ◽  
High Yields

<p>We present an enzyme engineering approach based solely on amino-acids sequence to convert glycoside hydrolases into transglycosylases. We demonstrate its effectiveness on enzymes form five different glycoside hydrolase families, synthesizing various oligosaccharides containing different α-/β-pyranosides or furanosides in one-step with high yields.</p>

scholarly journals Rational Enzyme Design Without Structural Knowledge: A Sequence-Based Approach for Efficient Generation of Glycosylation Catalysts

2020 ◽  
Author(s):  
David Teze ◽  
Zhao, Jiao ◽  
Mathias Wiemann ◽  
Zubaida Gulshan Kazi ◽  
Rossana Lupo ◽  
...  
Keyword(s):  
Amino Acids ◽  
Glycoside Hydrolase ◽  
Enzyme Engineering ◽  
Glycoside Hydrolases ◽  
Structural Knowledge ◽  
Enzyme Design ◽  
Engineering Approach ◽  
Efficient Generation ◽  
One Step ◽  
High Yields

<p>We present an enzyme engineering approach based solely on amino-acids sequence to convert glycoside hydrolases into transglycosylases. We demonstrate its effectiveness on enzymes form five different glycoside hydrolase families, synthesizing various oligosaccharides containing different α-/β-pyranosides or furanosides in one-step with high yields.</p>

scholarly journals Rational Enzyme Design Without Structural Knowledge: A Sequence-Based Approach for Effi-Cient Generation of Glycosylation Catalysts

2020 ◽  
Author(s):  
David Teze ◽  
Zhao, Jiao ◽  
Mathias Wiemann ◽  
Zubaida Gulshan Kazi ◽  
Rossana Lupo ◽  
...  
Keyword(s):  
Amino Acids ◽  
Glycoside Hydrolase ◽  
Enzyme Engineering ◽  
Glycoside Hydrolases ◽  
Structural Knowledge ◽  
Enzyme Design ◽  
Engineering Approach ◽  
One Step ◽  
High Yields

<p>We present an enzyme engineering approach based solely on amino-acids sequence to convert glycoside hydrolases into transglycosylases. We demonstrate its effectiveness on enzymes form five different glycoside hydrolase families, synthesizing various oligosaccharides containing different α-/β-pyranosides or furanosides in one-step with high yields.</p>

The IJCAI-09 Workshop on Learning Structural Knowledge From Observations (STRUCK-09)

AI Magazine ◽  
2010 ◽  
Vol 31 (1) ◽  
pp. 101
Author(s):  
Ugur Kuter ◽  
Hector Munoz-Avila
Keyword(s):  
Artificial Intelligence ◽  
Structural Knowledge ◽  
Group Discussions ◽  
Joint Conference ◽  
International Joint

The IJCAI-09 Workshop on Learning Structural Knowledge From Observations (STRUCK-09) took place as part of the International Joint Conference on Artificial Intelligence (IJCAI-09) on July 12 in Pasadena, California. The workshop program included paper presentations, discussion sessions about those papers, group discussions about two selected topic and a joint discussion.

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