Characterization of Solid Counterfeit Drug Samples by Desorption Electrospray Ionization and Direct-analysis-in-real-time Coupled to Time-of-flight Mass Spectrometry

ChemMedChem ◽  
2006 ◽  
Vol 1 (7) ◽  
pp. 702-705 ◽  
Author(s):  
Facundo M. Fernández ◽  
Robert B. Cody ◽  
Michael D. Green ◽  
Christina Y. Hampton ◽  
Rose McGready ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Electrospray Ionization ◽  
Real Time ◽  
Time Of Flight ◽  
Desorption Electrospray Ionization ◽  
Direct Analysis ◽  
Counterfeit Drug ◽  
Flight Mass Spectrometry

Characterization of a Chinese lignite and the corresponding derivatives using direct analysis in real time quadrupole time-of-flight mass spectrometry

RSC Advances ◽  
2016 ◽  
Vol 6 (107) ◽  
pp. 105780-105785 ◽  
Author(s):  
Xing Fan ◽  
Chu-Fan Wang ◽  
Chun-Yan You ◽  
Xian-Yong Wei ◽  
Lu Chen ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Solid State ◽  
Real Time ◽  
Time Of Flight ◽  
Direct Analysis ◽  
Ionization Technique ◽  
Flight Mass Spectrometry ◽  
Tof Ms

Direct analysis in real time ionization technique coupled with a quadrupole time-of-flight mass spectrometry (Q-TOF MS) was applied to characterize raw coal and coal derivatives in the solid state.

scholarly journals Thermal Properties, Isothermal Decomposition by Direct Analysis in Real-Time-Of-Flight Mass Spectrometry and Non Isothermal Crystallization Kinetics of Poly(Ethylene-Co-Vinyl Alcohol)/Poly(ε-Caprolactone) Blend

Crystals ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 292
Author(s):  
Abdulaziz Ali Alghamdi ◽  
Hussain Alattas ◽  
Waseem Sharaf Saeed ◽  
Abdel-Basit Al-Odayni ◽  
Ahmed Yacine Badjah Hadj Ahmed ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Real Time ◽  
Crystallization Kinetics ◽  
Isothermal Crystallization ◽  
Vinyl Alcohol ◽  
Time Of Flight ◽  
Direct Analysis ◽  
Isothermal Crystallization Kinetics ◽  
Flight Mass Spectrometry ◽  
Poly Ethylene

A series of poly(ethylene-co-vinyl alcohol)/poly(ε-caprolactone) blends with different compositions were prepared using solvent casting. The miscibility of this pair of polymers was investigated using differential scanning calorimetry (DSC), and proved by a negative Flory interaction parameter value calculated from the Nishi–Wang equation. The miscibility of this blend was also confirmed by scanning electronic microscopy (SEM). The thermal behaviors of the obtained materials were investigated by DSC, thermogravimetric analysis, and direct analysis in real-time–time-of-flight mass spectrometry and the results obtained were very relevant. Furthermore, the crystalline properties of the obtained materials were studied by DSC and X-ray diffraction where the Ozawa approach was adopted to investigate the non-isothermal crystallization kinetics. The results obtained revealed that this approach described the crystallization process well.

Ionization characteristics of glycosides by direct analysis in real time quadrupole-time of flight mass spectrometry

2017 ◽  
Vol 41 (3) ◽  
pp. 1103-1109 ◽  
Author(s):  
Hongmei Yang ◽  
Ge Gao ◽  
Yihan Wang ◽  
Jinrong Liu ◽  
Zongjun Li ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Real Time ◽  
Time Of Flight ◽  
Direct Analysis ◽  
Molecular Ion ◽  
Ion Formation ◽  
Flight Mass Spectrometry

Glycosides were ionized via various different reactions including (de)protonation, molecular ion formation, ISD fragmentation, and the formation of adducts.

Screening of psychoactive components in fresh khat using direct analysis in real time-time of flight-mass spectrometry

2018 ◽  
Vol 1 (3) ◽  
pp. 45 ◽  
Author(s):  
AbdulrhmanM Dhabbah ◽  
AYacine Badjah-Hadj-Ahmed ◽  
AliI Alawi ◽  
WaleedAbdulaziz Al Angari ◽  
BaselF Alrayes
Keyword(s):  
Mass Spectrometry ◽  
Real Time ◽  
Time Of Flight ◽  
Direct Analysis ◽  
Flight Mass Spectrometry

Rapid Detection and Characterization of Steroidal Saponins in the Root of Asparagus cochinchinensis by High-Performance Liquid Chromatography Coupled to Electrospray Ionization and Quadrupole Time-of-Flight Mass Spectrometry

2020 ◽  
Vol 58 (5) ◽  
pp. 454-463
Author(s):  
Yun Ling ◽  
Xin He ◽  
Renliang Jiang ◽  
Qi Zhang ◽  
Shuqin Yuan ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Electrospray Ionization ◽  
High Performance ◽  
Time Of Flight ◽  
Steroidal Saponins ◽  
Flight Mass Spectrometry ◽  
Asparagus Cochinchinensis

Abstract The dried root of Asparagus cochinchinensis (RAC) has been used as an important traditional Chinese medicine for a long time in China. Steroidal saponins (SSs) are considered to be the main active ingredients of this herb. However, the isolation and structural determination of SSs from RAC are time-consuming and laborious. For this reason, the development of new methods for the separation and characterization of SSs is highly desirable. In this study, a new high-performance liquid chromatography coupled to electrospray ionization and quadrupole time-of-flight mass spectrometry (HPLC-ESI-QTOF-MS/MS) method with precursor ions and the corresponding fragment ions was developed for the identification of SSs in RAC. Finally, 30 SSs have been detected and identified, including 17 potential new compounds. This is the first systematic study of SSs in RAC by HPLC-ESI-QTOF-MS/MS method.

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