Clear-cell adenocarcinoma of the female genital tract: Presence of Hyaline stroma and tigroid background in various types of cytologic specimens

2005 ◽  
Vol 32 (6) ◽  
pp. 336-340 ◽  
Author(s):  
Surapan Khunamornpong ◽  
Paul S. Thorner ◽  
Prapaporn Suprasert ◽  
Sumalee Siriaunkgul
Keyword(s):  
Genital Tract ◽  
Clear Cell ◽  
Female Genital Tract ◽  
Clear Cell Adenocarcinoma ◽  
Female Genital

Clear Cell Adenocarcinoma of the Female Genital Tract: Long-Term Outcome and Fertility Aspects After Brachytherapy Aimed at a Conservative Treatment

2012 ◽  
Vol 22 (8) ◽  
pp. 1378-1382 ◽  
Author(s):  
Nicolas Magné ◽  
Cyrus Chargari ◽  
Antonin Levy ◽  
Carlos Rodriguez ◽  
Véronique De Vos ◽  
...  
Keyword(s):  
Conservative Treatment ◽  
Pregnancy Rate ◽  
Genital Tract ◽  
Clear Cell ◽  
Female Genital Tract ◽  
Disease Free Survival ◽  
Good Survival ◽  
Clear Cell Adenocarcinoma ◽  
Long Term Outcome ◽  
Female Genital

ObjectivesTo assess the outcome and the fertility aspects in the particular population of cervical and/or vaginal clear cell adenocarcinoma (CCA) associated or not to previous in utero diethylstilbestrol exposure.MethodsFrom January 1970 to December 2003, data from 61 consecutive patients with cervical and/or vaginal histologically proven CCA treated with brachytherapy (BT) aimed at a conservative treatment at the Institut Gustave Roussy as a part of treatment were retrospectively analyzed.ResultsThe median follow-up was 9.4 years, ranging from 0.3 to 27.4 years. The 5-year specific overall survival rate was 79%. The median time of disease-free survival was 5.8 years. In the subgroup of 42 patients with a cervical CCA, 12 patients tried to be pregnant, 2 patients became pregnant and had miscarriages (P2M2 and P1M1). No pregnancy has been observed in 10 patients exclusively owing to anomalies of the reproductive tract: 6 patients had partial or total diaphragm, 2 patients had an anatomical alteration of the uterus, 1 patient had atrophic endometrium, and 1 patient had primary infertility. In the subgroup of 19 patients with a vaginal CCA, 7 patients tried to be pregnant. All of them had no morphological and/or functional anomalies of the genital tract. Three of 7 patients had delivered healthy babies (P1D1, P2D2, and P3M2D1), and another one had a miscarriage (P1M1). Moreover, all babies were delivered by cesarean section. The pregnancy rate was 10% (6 of 61 patients) with 3 healthy babies.ConclusionConservative approach in patients with female genital tract CCA including BT gives good results with good survival rates and an interesting global pregnancy rate.

Prenatal exposure to stilbestrol and adenocarcinoma of the female genital tract: The pediatrician's responsibility

PEDIATRICS ◽  
1975 ◽  
Vol 55 (4) ◽  
pp. 456-458
Author(s):  
Lester F. Soyka
Keyword(s):  
Young Women ◽  
Genital Tract ◽  
Clear Cell ◽  
Female Genital Tract ◽  
In Utero ◽  
Vaginal Examination ◽  
Cell Type ◽  
Clear Cell Type ◽  
The Media ◽  
Female Genital

In 1970 Herbst and Scully1 reported seven cases of adenocarcinoma of the vagina in adolescents, of which six were of the clear-cell type. In a followup paper,2 an association was proposed between the occurrence of this previously rare tumor in young women and their exposure in utero to diethylstilbestrol (DES). This startling conclusion was immediately strengthened by reports of additional cases, and soon adenocarcinoma of the cervix also was linked to in utero DES exposure.3 These reports have been popularized by the media, and some obstetricians have recommended routine, repeated vaginal examination, biopsy, culposcopy, etc. for all females who were exposed in utero.4-6

Cytologic Features of Clear Cell Carcinoma of the Female Genital Tract

2004 ◽  
Vol 48 (1) ◽  
pp. 47-51 ◽  
Author(s):  
José A. Jiménez-Heffernan ◽  
Blanca Vicandi ◽  
Pilar González-Peramato ◽  
Ana Pérez-Campos ◽  
Pilar López-Ferrer ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Genital Tract ◽  
Clear Cell ◽  
Clear Cell Carcinoma ◽  
Female Genital Tract ◽  
Female Genital

Genital Tract Metastases from Renal Cell Carcinoma—A Case Report and Discussion

1985 ◽  
Vol 30 (1) ◽  
pp. 43-45 ◽  
Author(s):  
N. D. Sharma ◽  
G. B. McKelvie
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Genital Tract ◽  
World Literature ◽  
Clear Cell ◽  
Female Genital Tract ◽  
Clear Cell Adenocarcinoma ◽  
Menopausal Woman ◽  
First Case

A case of renal cell carcinoma presenting with metastases in the female genital tract is reported. Clinical and histological features distinguishing primary and secondary clear cell adenocarcinoma of the genital tract are discussed. It is emphasised that when a clear cell adenocarcinoma is found, particularly in a post-menopausal woman, metastatic renal carcinoma has to be excluded. Although so far there are 61 cases reported in the world literature from English speaking countries, we believe that this is the first case reported from the United Kingdom.

Cytology of Clear Cell Carcinoma of the Female Genital Tract in Fine Needle Aspirates and Ascites

2000 ◽  
Vol 44 (6) ◽  
pp. 1005-1009 ◽  
Author(s):  
Şafak Atahan ◽  
Cemil Ekinci ◽  
Fikri İçli ◽  
Nural Erdoğan
Keyword(s):  
Cell Carcinoma ◽  
Genital Tract ◽  
Clear Cell ◽  
Clear Cell Carcinoma ◽  
Female Genital Tract ◽  
Fine Needle ◽  
Fine Needle Aspirates ◽  
Female Genital
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