Highly Enantioselective Michael Addition of 3-Aryloxindoles to Phenyl Vinyl Sulfone Catalyzed by Cinchona Alkaloid-Derived Bifunctional Amine-Thiourea Catalysts Bearing Sulfonamide as Multiple Hydrogen-Bonding Donors

2011 ◽  
Vol 2011 (30) ◽  
pp. 6078-6084 ◽  
Author(s):  
Mei-Xin Zhao ◽  
Wen-Hao Tang ◽  
Ming-Xiao Chen ◽  
Deng-Ke Wei ◽  
Tong-Lei Dai ◽  
...  
Keyword(s):  
Hydrogen Bonding ◽  
Michael Addition ◽  
Cinchona Alkaloid ◽  
Vinyl Sulfone ◽  
Multiple Hydrogen Bonding ◽  
Phenyl Vinyl

Novel ferrocene-based bifunctional amine–thioureas for asymmetric Michael addition of acetylacetone to nitroolefins

2015 ◽  
Vol 13 (17) ◽  
pp. 5054-5060 ◽  
Author(s):  
Xiaochen Ren ◽  
Chunyan He ◽  
Yingle Feng ◽  
Yonghai Chai ◽  
Wei Yao ◽  
...  
Keyword(s):  
Hydrogen Bonding ◽  
Efficient Method ◽  
Michael Addition ◽  
High Yield ◽  
Bifunctional Catalysts ◽  
Michael Adducts ◽  
Asymmetric Michael Addition ◽  
Multiple Hydrogen Bonding

An efficient method was developed to synthesize the ferrocene-based bifunctional amine–thioureas bearing multiple hydrogen-bonding donors. Asymmetric Michael addition of acetylacetone to nitroolefins catalyzed by these novel bifunctional catalysts affords the Michael adducts in high yield and moderate to excellent enantioselectivities.

Asymmetric Michael addition of chiral enaminoesters to phenyl vinyl sulfone and 1,1-bis(phenylsulfonyl)ethylene

1992 ◽  
Vol 3 (8) ◽  
pp. 1003-1006 ◽  
Author(s):  
Sergio Pinheiro ◽  
André Guinganta ◽  
Didier Desmaële ◽  
Jean d'Angelo
Keyword(s):  
Michael Addition ◽  
Vinyl Sulfone ◽  
Asymmetric Michael Addition ◽  
Phenyl Vinyl
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