scholarly journals Reduction in sample injection bias using pressure gradients generated on chip

2021 ◽  
Author(s):  
Yukari Liu ◽  
Ling Xia ◽  
Debashis Dutta
Keyword(s):  
Pressure Gradients ◽  
Sample Injection ◽  
On Chip

Pressure-Driven Sample Injection with Quantitative Liquid Dispensing for On-Chip Electrophoresis

2004 ◽  
Vol 20 (3) ◽  
pp. 483-487 ◽  
Author(s):  
Nae Yoon LEE ◽  
Masumi YAMADA ◽  
Minoru SEKI
Keyword(s):  
Sample Injection ◽  
On Chip ◽  
Pressure Driven

Hand-held syringe as a portable plastic pump for on-chip continuous-flow PCR: miniaturization of sample injection device

The Analyst ◽  
2012 ◽  
Vol 137 (4) ◽  
pp. 983-990 ◽  
Author(s):  
Wenming Wu ◽  
Kieu The Loan Trinh ◽  
Nae Yoon Lee
Keyword(s):  
Continuous Flow ◽  
Injection Device ◽  
Sample Injection ◽  
On Chip

scholarly journals Development of an on-chip sample injection system with a 6-port valve incorporated in a microchip

RSC Advances ◽  
2020 ◽  
Vol 10 (59) ◽  
pp. 35848-35855
Author(s):  
Kazuhiro Morioka ◽  
Hina Sato ◽  
Kenji Morita ◽  
Hemmi Akihide ◽  
Hizuru Nakajima ◽  
...  
Keyword(s):  
Injection System ◽  
Sample Injection ◽  
Chip Sample ◽  
On Chip

We demonstrate on-chip sample injection using a 6-port valve incorporated in a microchip.

On-chip definition of picolitre sample injection plugs for miniaturised liquid chromatography

2001 ◽  
Vol 924 (1-2) ◽  
pp. 259-263 ◽  
Author(s):  
Alan P. O’Neill ◽  
Peter O’Brien ◽  
John Alderman ◽  
Daniel Hoffman ◽  
Máiréad McEnery ◽  
...  
Keyword(s):  
Liquid Chromatography ◽  
Sample Injection ◽  
On Chip ◽  
Definition Of

Gut microbiome a promising target for management of respiratory diseases

2020 ◽  
Vol 477 (14) ◽  
pp. 2679-2696
Author(s):  
Riddhi Trivedi ◽  
Kalyani Barve
Keyword(s):  
Respiratory Diseases ◽  
New Technology ◽  
Bacterial Flora ◽  
Systemic Circulation ◽  
The Body ◽  
Lung Pathology ◽  
Promising Target ◽  
Current Therapies ◽  
Intestinal Microbial Flora ◽  
On Chip

The intestinal microbial flora has risen to be one of the important etiological factors in the development of diseases like colorectal cancer, obesity, diabetes, inflammatory bowel disease, anxiety and Parkinson's. The emergence of the association between bacterial flora and lungs led to the discovery of the gut–lung axis. Dysbiosis of several species of colonic bacteria such as Firmicutes and Bacteroidetes and transfer of these bacteria from gut to lungs via lymphatic and systemic circulation are associated with several respiratory diseases such as lung cancer, asthma, tuberculosis, cystic fibrosis, etc. Current therapies for dysbiosis include use of probiotics, prebiotics and synbiotics to restore the balance between various species of beneficial bacteria. Various approaches like nanotechnology and microencapsulation have been explored to increase the permeability and viability of probiotics in the body. The need of the day is comprehensive study of mechanisms behind dysbiosis, translocation of microbiota from gut to lung through various channels and new technology for evaluating treatment to correct this dysbiosis which in turn can be used to manage various respiratory diseases. Microfluidics and organ on chip model are emerging technologies that can satisfy these needs. This review gives an overview of colonic commensals in lung pathology and novel systems that help in alleviating symptoms of lung diseases. We have also hypothesized new models to help in understanding bacterial pathways involved in the gut–lung axis as well as act as a futuristic approach in finding treatment of respiratory diseases caused by dysbiosis.

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