Review for "Aging mechanisms – A perspective mostly from Drosophila"

2019 ◽  
Author(s):  
Jason Wood
Keyword(s):  
Aging Mechanisms

scholarly journals Quantification of aging mechanisms of carbon-coated and uncoated silicon thin film anodes in lithium metal and lithium ion cells

2021 ◽  
Vol 41 ◽  
pp. 102812
Author(s):  
Simone Casino ◽  
Thomas Beuse ◽  
Verena Küpers ◽  
Markus Börner ◽  
Tobias Gallasch ◽  
...  
Keyword(s):  
Thin Film ◽  
Lithium Ion ◽  
Lithium Metal ◽  
Silicon Thin Film ◽  
Lithium Ion Cells ◽  
Carbon Coated ◽  
Aging Mechanisms

scholarly journals Molecular and cellular pathways contributing to brain aging

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Aliabbas Zia ◽  
Ali Mohammad Pourbagher-Shahri ◽  
Tahereh Farkhondeh ◽  
Saeed Samarghandian
Keyword(s):  
Neurodegenerative Diseases ◽  
Neurodegenerative Disorders ◽  
Brain Aging ◽  
Neuroprotective Effect ◽  
Ros Generation ◽  
Brain Health ◽  
Cellular Pathways ◽  
Aging Mechanisms ◽  
Oxidatively Modified ◽  
Biology Of Aging

AbstractAging is the leading risk factor for several age-associated diseases such as neurodegenerative diseases. Understanding the biology of aging mechanisms is essential to the pursuit of brain health. In this regard, brain aging is defined by a gradual decrease in neurophysiological functions, impaired adaptive neuroplasticity, dysregulation of neuronal Ca2+ homeostasis, neuroinflammation, and oxidatively modified molecules and organelles. Numerous pathways lead to brain aging, including increased oxidative stress, inflammation, disturbances in energy metabolism such as deregulated autophagy, mitochondrial dysfunction, and IGF-1, mTOR, ROS, AMPK, SIRTs, and p53 as central modulators of the metabolic control, connecting aging to the pathways, which lead to neurodegenerative disorders. Also, calorie restriction (CR), physical exercise, and mental activities can extend lifespan and increase nervous system resistance to age-associated neurodegenerative diseases. The neuroprotective effect of CR involves increased protection against ROS generation, maintenance of cellular Ca2+ homeostasis, and inhibition of apoptosis. The recent evidence about the modem molecular and cellular methods in neurobiology to brain aging is exhibiting a significant potential in brain cells for adaptation to aging and resistance to neurodegenerative disorders.

scholarly journals Rodent studies of developmental programming and aging mechanisms

2021 ◽  
Author(s):  
Elena Zambrano ◽  
Consuelo Lomas Soria ◽  
Peter W. Nathanielsz
Keyword(s):  
Developmental Programming ◽  
Aging Mechanisms

scholarly journals Polyethylene Nanocomposites for Power Cable Insulations

Polymers ◽  
2018 ◽  
Vol 11 (1) ◽  
pp. 24 ◽  
Author(s):  
Ilona Pleşa ◽  
Petru Noţingher ◽  
Cristina Stancu ◽  
Frank Wiesbrock ◽  
Sandra Schlögl
Keyword(s):  
Electrical Performance ◽  
Power Cable ◽  
Power Cables ◽  
Structure Property ◽  
Thermoplastic Polymers ◽  
Water Tree ◽  
Tree Resistance ◽  
Structure Property Relationships ◽  
Aging Mechanisms ◽  
Comprehensive Study

This review represents a comprehensive study of nanocomposites for power cables insulations based on thermoplastic polymers such as polyethylene congeners like LDPE, HDPE and XLPE, which is complemented by original results. Particular focus lies on the structure-property relationships of nanocomposites and the materials’ design with the corresponding electrical properties. The critical factors, which contribute to the degradation or improvement of the electrical performance of such cable insulations, are discussed in detail; in particular, properties such as electrical conductivity, relative permittivity, dielectric losses, partial discharges, space charge, electrical and water tree resistance behavior and electric breakdown of such nanocomposites based on thermoplastic polymers are described and referred to the composites’ structures. This review is motivated by the fact that the development of polymer nanocomposites for power cables insulation is based on understanding more closely the aging mechanisms and the behavior of nanocomposites under operating stresses.

scholarly journals Aging Mechanisms of Electrode Materials in Lithium-Ion Batteries for Electric Vehicles

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Cheng Lin ◽  
Aihua Tang ◽  
Hao Mu ◽  
Wenwei Wang ◽  
Chun Wang
Keyword(s):  
Lithium Ion Batteries ◽  
Electrode Materials ◽  
Electrochemical Behaviour ◽  
Lithium Ion ◽  
Storage Conditions ◽  
Carbon Anode ◽  
Side Reactions ◽  
Metallic Oxide ◽  
Lithium Ions ◽  
Aging Mechanisms

Electrode material aging leads to a decrease in capacity and/or a rise in resistance of the whole cell and thus can dramatically affect the performance of lithium-ion batteries. Furthermore, the aging phenomena are extremely complicated to describe due to the coupling of various factors. In this review, we give an interpretation of capacity/power fading of electrode-oriented aging mechanisms under cycling and various storage conditions for metallic oxide-based cathodes and carbon-based anodes. For the cathode of lithium-ion batteries, the mechanical stress and strain resulting from the lithium ions insertion and extraction predominantly lead to structural disordering. Another important aging mechanism is the metal dissolution from the cathode and the subsequent deposition on the anode. For the anode, the main aging mechanisms are the loss of recyclable lithium ions caused by the formation and increasing growth of a solid electrolyte interphase (SEI) and the mechanical fatigue caused by the diffusion-induced stress on the carbon anode particles. Additionally, electrode aging largely depends on the electrochemical behaviour under cycling and storage conditions and results from both structural/morphological changes and side reactions aggravated by decomposition products and protic impurities in the electrolyte.

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