scholarly journals Efficacy of interferon alfa therapy in chronic hepatitis C patients depends primarily on hepatitis C virus RNA level

Hepatology ◽  
1995 ◽  
Vol 22 (5) ◽  
pp. 1351-1354 ◽  
Author(s):  
Gotaro Yamada ◽  
Masahiro Takatani ◽  
Fumitoshi Kishi ◽  
Michiko Takahashi ◽  
Toshihiko Doi ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Interferon Alfa ◽  
Hepatitis C Virus Rna ◽  
Virus Rna ◽  
Chronic Hepatitis C Patients

Serum Hepatitis C Virus RNA Levels in Chronic Hepatitis C-Importance for outcome of interferon alfa-2b treatment

1994 ◽  
Vol 26 (3) ◽  
pp. 263-270 ◽  
Author(s):  
Zhi Bing Yun ◽  
Olle Reichard ◽  
Margaret Chen ◽  
Joakim Lundeberg ◽  
Gunnar Norkrans ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Interferon Alfa ◽  
Serum Hepatitis ◽  
Hepatitis C Virus Rna ◽  
Virus Rna ◽  
Rna Levels

scholarly journals Delayed Viral Clearance after 6-Week Treatment with Peginterferon Plus Ribavirin in a Patient with Chronic Hepatitis C Virus Genotype 1b

2016 ◽  
Vol 10 (2) ◽  
pp. 417-422 ◽  
Author(s):  
Akira Sato ◽  
Toshiya Ishii ◽  
Kayo Adachi ◽  
Hideaki Takahashi ◽  
Fumiaki Sano ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Viral Clearance ◽  
Hepatitis C Virus Infection ◽  
Hepatitis C Virus Rna ◽  
Virus Genotype ◽  
Virus Rna ◽  
Chronic Hepatitis C Virus

Following interferon-based therapy for chronic hepatitis C, the negativity of hepatitis C virus RNA is essential to achieve viral clearance at the end of treatment. We report a case of clearance of chronic hepatitis C virus infection following early discontinuation (at 6 weeks) of peginterferon plus ribavirin therapy, without negativity for hepatitis C virus RNA during the treatment period. The patient was a 76-year-old Japanese male infected with hepatitis C virus genotype 1b and TT of IL28B rs8099917. Hepatitis C virus RNA remained positive at persistently low levels for more than 2 months after the cessation of therapy and became negative at 7 months after the discontinuation of therapy. Spontaneous clearance of hepatitis C virus RNA can occur following antiviral failure in patients with persistently low viral loads, and virological follow-up is therefore necessary in chronic hepatitis C virus infection, even after antiviral failure.

Sign in / Sign up

Export Citation Format

Share Document