Comparative evaluation of the diagnostic performance of autofluorescence and diffuse reflectance in oral cancer detection: a clinical study

2011 ◽  
Vol 4 (10) ◽  
pp. 696-706 ◽  
Author(s):  
Jayaraj L. Jayanthi ◽  
Narayanan Subhash ◽  
Manju Stephen ◽  
Emmanuel K. Philip ◽  
Valappil T. Beena
2006 ◽  
Vol 11 (1) ◽  
pp. 014018 ◽  
Author(s):  
N. Subhash ◽  
J. R. Mallia ◽  
S. S. Thomas ◽  
A. Mathews ◽  
P. Sebastian ◽  
...  

2019 ◽  
Vol 9 (1) ◽  
pp. 05-09
Author(s):  
Chitra Chakravarthy ◽  
◽  
Siddarth Goudar ◽  
Sanjay Sundar ◽  
Ravi Patil ◽  
...  

2021 ◽  
Vol 28 (1) ◽  
Author(s):  
Neda Gholizadeh ◽  
Peter B. Greer ◽  
John Simpson ◽  
Jonathan Goodwin ◽  
Caixia Fu ◽  
...  

Abstract Background Current multiparametric MRI (mp-MRI) in routine clinical practice has poor-to-moderate diagnostic performance for transition zone prostate cancer. The aim of this study was to evaluate the potential diagnostic performance of novel 1H magnetic resonance spectroscopic imaging (MRSI) using a semi-localized adiabatic selective refocusing (sLASER) sequence with gradient offset independent adiabaticity (GOIA) pulses in addition to the routine mp-MRI, including T2-weighted imaging (T2WI), diffusion-weighted imaging (DWI) and quantitative dynamic contrast enhancement (DCE) for transition zone prostate cancer detection, localization and grading. Methods Forty-one transition zone prostate cancer patients underwent mp-MRI with an external phased-array coil. Normal and cancer regions were delineated by two radiologists and divided into low-risk, intermediate-risk, and high-risk categories based on TRUS guided biopsy results. Support vector machine models were built using different clinically applicable combinations of T2WI, DWI, DCE, and MRSI. The diagnostic performance of each model in cancer detection was evaluated using the area under curve (AUC) of the receiver operating characteristic diagram. Then accuracy, sensitivity and specificity of each model were calculated. Furthermore, the correlation of mp-MRI parameters with low-risk, intermediate-risk and high-risk cancers were calculated using the Spearman correlation coefficient. Results The addition of MRSI to T2WI + DWI and T2WI + DWI + DCE improved the accuracy, sensitivity and specificity for cancer detection. The best performance was achieved with T2WI + DWI + MRSI where the addition of MRSI improved the AUC, accuracy, sensitivity and specificity from 0.86 to 0.99, 0.83 to 0.96, 0.80 to 0.95, and 0.85 to 0.97 respectively. The (choline + spermine + creatine)/citrate ratio of MRSI showed the highest correlation with cancer risk groups (r = 0.64, p < 0.01). Conclusion The inclusion of GOIA-sLASER MRSI into conventional mp-MRI significantly improves the diagnostic accuracy of the detection and aggressiveness assessment of transition zone prostate cancer.


2016 ◽  
Author(s):  
M. Chakraborty ◽  
S. Mukhopadhyay ◽  
A. Dasgupta ◽  
S. Banerjee ◽  
S. Mukhopadhyay ◽  
...  

1981 ◽  
Vol 74 (5special) ◽  
pp. 1025-1037
Author(s):  
Midori Hori ◽  
Yasuro Miyoshi ◽  
Yasuo Sakakura ◽  
Kotaro Ukai ◽  
Mikikazu Yamagiwa ◽  
...  
Keyword(s):  

2018 ◽  
Vol 16 (1) ◽  
Author(s):  
Xiao-Jie Chen ◽  
Xue-Qiong Zhang ◽  
Qi Liu ◽  
Jing Zhang ◽  
Gang Zhou

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