A threshold dosage of estrogen for male‐to‐female sex reversal in the Glandirana rugosa frog

Author(s):  
Akira Oike ◽  
Yoriko Nakamura ◽  
Shigeki Yasumasu ◽  
Etsuro Ito ◽  
Masahisa Nakamura
2020 ◽  
Vol 32 (6) ◽  
pp. 938-941 ◽  
Author(s):  
Maria M. Martinez ◽  
Mónica Costa ◽  
Cecilia Ratti

Male-to-female sex reversal in horses is a developmental disorder in which phenotypic females have a male genetic constitution. Male-to-female sex reversal is the second most common genetic sex abnormality, after X chromosome monosomy. All male-to-female sex reversal cases studied to date have been found to be infertile. Therefore, a screening test is particularly useful in laboratories doing DNA genotyping in horses. Our laboratory has tested > 209,000 horses for parentage using a panel of microsatellite markers and the sex marker gene amelogenin ( AMEL). Suspect XY sex reversal cases are reported females with a male profile by AMEL testing. After routine genotyping, 49 cases were detected and further tested using the sex-determining region Y ( SRY) gene, confirming the XY SRY-negative genotype of suspect sex reversal cases. When some inconsistencies arose in the initial result, a molecular panel of X- and Y-linked markers was analyzed for these samples. Of the 49 cases, 33 were confirmed as XY SRY-negative. The remaining 16 cases were identified as false-positives as a result of anomalies of AMEL testing in horses.


Nature ◽  
10.1038/31482 ◽  
1998 ◽  
Vol 393 (6686) ◽  
pp. 688-692 ◽  
Author(s):  
Yuko Katoh-Fukui ◽  
Reiko Tsuchiya ◽  
Toshihiko Shiroishi ◽  
Yoko Nakahara ◽  
Naoko Hashimoto ◽  
...  

Cell ◽  
2001 ◽  
Vol 104 (6) ◽  
pp. 875-889 ◽  
Author(s):  
Jennifer S. Colvin ◽  
Rebecca P. Green ◽  
Jennifer Schmahl ◽  
Blanche Capel ◽  
David M. Ornitz

1994 ◽  
Vol 7 (4) ◽  
pp. 497-501 ◽  
Author(s):  
B. Bardoni ◽  
E. Zanaria ◽  
S. Guioli ◽  
G. Floridia ◽  
K. C. Worley ◽  
...  

2008 ◽  
Vol 17 (19) ◽  
pp. 2949-2955 ◽  
Author(s):  
Danielle M. Maatouk ◽  
Leo DiNapoli ◽  
Ashley Alvers ◽  
Keith L. Parker ◽  
Makoto M. Taketo ◽  
...  

2007 ◽  
Vol 122 (1) ◽  
pp. 63-70 ◽  
Author(s):  
Marta Smyk ◽  
Jonathan S. Berg ◽  
Amber Pursley ◽  
Fiona K. Curtis ◽  
Bridget A. Fernandez ◽  
...  

2014 ◽  
Vol 81 (12) ◽  
pp. 1146-1158 ◽  
Author(s):  
Vincent Gennotte ◽  
Charles Mélard ◽  
Helena D'Cotta ◽  
Jean-François Baroiller ◽  
Carole Rougeot

Sign in / Sign up

Export Citation Format

Share Document