Reproducibility of Longitudinal Changes in Cortical Thickness Determined by Surface‐Based Morphometry Between Non‐Accelerated and Accelerated MR Imaging

2021 ◽  
Author(s):  
Hidemasa Takao ◽  
Shiori Amemiya ◽  
Osamu Abe ◽  
Keyword(s):  
Mr Imaging ◽  
Cortical Thickness ◽  
Longitudinal Changes ◽  
Surface Based Morphometry

Brain Structural Plasticity Associated with Maternal Caregiving in Mothers: A Voxel- and Surface-Based Morphometry Study

2019 ◽  
Vol 19 (5-6) ◽  
pp. 192-203 ◽  
Author(s):  
Kaihua Zhang ◽  
Mengxing Wang ◽  
Jilei Zhang ◽  
Xiaoxia Du ◽  
Zhong Chen
Keyword(s):  
Cortical Thickness ◽  
Postpartum Period ◽  
Structural Changes ◽  
Functional Neuroimaging ◽  
Middle Temporal Gyrus ◽  
Precentral Gyrus ◽  
Structural Dynamic ◽  
Longitudinal Changes ◽  
Maternal Caregiving ◽  
Surface Based Morphometry

Background: Pregnancy constitutes a significant period in the lives of women, after which they often experience numerous crucial physiological and psychological changes. Functional neuroimaging studies have shown longitudinal changes in functional brain activity in mothers responding to infant-related stimuli. However, the structural changes that occur in the brains of mothers after delivery remain to be explored. Objective: We aimed to evaluate the structural changes in mothers during the postpartum phase. Methods: We recruited 35 primiparous mothers and 26 nonmothers to participate in this voxel- and surface-based morphometry study, and 22 mothers were scanned twice with a follow-up of approximately 2 years. Results: Compared to nonmothers, mothers exhibited reduced gray matter (GM) volumes and increased white matter (WM) volumes in regions associated with empathy and reward networks (supplementary motor area, precuneus, inferior parietal lobe, insula, and striatum), decreased cortical thickness in the precentral gyrus and increased gyrification index in the orbitofrontal cortex. Furthermore, mothers showed longitudinal changes in the GM and WM volumes and cortical thickness of several of these regions (including the superior and medial frontal gyrus, insula, limbic lobe, superior and middle temporal gyrus, and precentral gyrus), which have been associated with maternal networks during the postpartum period. Additionally, the changes in GM and WM volumes were related to changes in empathetic abilities in mothers. Conclusion: These results suggest that the brains of mothers exhibit adaptive structural dynamic plasticity. These findings provide a neuroanatomical basis for understanding how mothers process emotional sensory information during the postpartum period.

P4-189: Effect of the APOE-ε4 allele on longitudinal changes in cortical thickness in normal aging

2012 ◽  
Vol 8 (4S_Part_19) ◽  
pp. P702-P703
Author(s):  
Tara Madhyastha ◽  
Paul Borghesani ◽  
Elizabeth Aylward ◽  
Monique Cherrier ◽  
Katie Askren ◽  
...  
Keyword(s):  
Cortical Thickness ◽  
Normal Aging ◽  
Longitudinal Changes ◽  
Apoe Ε4 ◽  
Ε4 Allele

scholarly journals Longitudinal changes in cocaine intake and cognition are linked to cortical thickness adaptations in cocaine users

2019 ◽  
Vol 21 ◽  
pp. 101652 ◽  
Author(s):  
Sarah Hirsiger ◽  
Jürgen Hänggi ◽  
Jürgen Germann ◽  
Matthias Vonmoos ◽  
Katrin H. Preller ◽  
...  
Keyword(s):  
Cortical Thickness ◽  
Longitudinal Changes ◽  
Cocaine Users

scholarly journals Electroconvulsive Therapy Induces Cortical Morphological Alterations in Major Depressive Disorder Revealed with Surface-Based Morphometry Analysis

2019 ◽  
Vol 29 (07) ◽  
pp. 1950005 ◽  
Author(s):  
Jinping Xu ◽  
Jiaojian Wang ◽  
Tongjian Bai ◽  
Xiaodong Zhang ◽  
Tian Li ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Surface Area ◽  
Cortical Thickness ◽  
Electroconvulsive Therapy ◽  
Therapeutic Efficacy ◽  
Support Vector ◽  
Major Depressive ◽  
Before And After ◽  
Surface Based Morphometry

Although electroconvulsive therapy (ECT) is one of the most effective treatments for major depressive disorder (MDD), the mechanism underlying the therapeutic efficacy and side effects of ECT remains poorly understood. Here, we investigated alterations in the cortical morphological measurements including cortical thickness (CT), surface area (SA), and local gyrification index (LGI) in 23 MDD patients before and after ECT. Furthermore, multivariate pattern analysis using linear support vector machine (SVM) was applied to investigate whether the changed morphological measurements can be effective indicators for therapeutic efficacy of ECT. Surface-based morphometry (SBM) analysis found significantly increased vertex-wise and regional cortical thickness (CT) and surface area (SA) in widespread regions, mainly located in the left insula (INS) and left fusiform gyrus, as well as hypergyrification in the left middle temporal gyrus (MTG) in MDD patients after ECT. Partial correlational analyses identified associations between the morphological properties and depressive symptom scores and impaired memory scores. Moreover, SVM result showed that the changed morphological measurements were effective to classify the MDD patients before and after ECT. Our findings suggested that ECT may enhance cortical neuroplasticity to facilitate neurogenesis to remit depressive symptoms and to impair delayed memory. These findings indicated that the cortical morphometry is a good index for therapeutic efficacy of ECT.

scholarly journals Differentiation between Subtypes of Primary Progressive Aphasia by Using Cortical Thickness and Diffusion-Tensor MR Imaging Measures

Radiology ◽  
2015 ◽  
Vol 276 (1) ◽  
pp. 219-227 ◽  
Author(s):  
Federica Agosta ◽  
Pilar M. Ferraro ◽  
Elisa Canu ◽  
Massimiliano Copetti ◽  
Sebastiano Galantucci ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Cortical Thickness ◽  
Diffusion Tensor ◽  
Primary Progressive Aphasia ◽  
Progressive Aphasia ◽  
Primary Progressive ◽  
And Diffusion ◽  
Diffusion Tensor Mr Imaging

scholarly journals PO-0863 Longitudinal Changes Of Cortical Thickness Following Premature Birth

2014 ◽  
Vol 99 (Suppl 2) ◽  
pp. A533.2-A533
Author(s):  
L Vasung ◽  
L Gui ◽  
C Borradori Tolsa ◽  
F Lazeyras ◽  
P Huppi
Keyword(s):  
Cortical Thickness ◽  
Premature Birth ◽  
Longitudinal Changes

scholarly journals Absence of changes in cortical thickness in patients with migraine

Cephalalgia ◽  
2011 ◽  
Vol 31 (14) ◽  
pp. 1452-1458 ◽  
Author(s):  
Ritobrato Datta ◽  
John A Detre ◽  
Geoffrey K Aguirre ◽  
Brett Cucchiara
Keyword(s):  
Cortical Thickness ◽  
Gray Matter ◽  
Visual Motion ◽  
Inverse Correlation ◽  
Motion Processing ◽  
Brain Anatomy ◽  
Cingulate Gyrus ◽  
Whole Brain ◽  
Visual Motion Processing ◽  
Surface Based Morphometry

Objective: Previous studies have reported gray matter alterations in patients with migraine, particularly thinning of the cingulate gyrus, and thickening of the somatosensory cortex (SSC) and visual motion processing areas (V3A/MT+). We attempted to replicate these findings in a larger patient population. Methods: Brain anatomy was collected with 3T MRI. Surface-based morphometry was used to segment each brain volume, reconstruct and inflate the cortical sheet, and estimate gray matter thickness. Results: Eighty-four age and sex-matched participants (28 migraine with aura, 28 migraine without aura, and 28 controls) were studied. No significant differences in somatosensory, cingulate gyrus, or V3A/MT+ cortical thickness were found between the groups, including analysis of specific subregions previously reported to be affected. Whole brain analysis found no regions of differential gray matter thickness between groups. A highly significant inverse correlation between age and whole brain and regional cortical thickness was identified. Power analyses indicate that even a small difference (∼0.07 to 0.14 mm) in cortical thickness could have been detected between groups given the sample size. Interpretation: Using highly sensitive surface-based morphometry, no differences in cortical thickness between patients with migraine and controls could be identified.

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