Primary antibiotic resistance of
            Helicobacter pylori
            isolates is twofold more frequent in HIV‐positive than HIV‐negative individuals: A descriptive observational study

Background: Endoscopy is the diagnostic test of choice for most HIV-associated GI diseases, as endoscopic and histopathologic evaluation can render diagnoses in patients with non-specific symptoms. The objective of the present research was to study the gastrointestinal endoscopic findings among HIV positive patients and compare them with HIV negative patients.Methods: A comparative study was carried out in the department of General Medicine to study the gastrointestinal endoscopic findings among HIV positive patients and compare them with HIV negative patients for a period of two years. 101 cases who were HIV positive were compared with equal number of HIV negative subjects. The subjects in the case group as well as control group were chosen randomly.Results: There was a significant lower incidence of Helicobacter pylori positivity (38.6%) among HIV positive patients when compared to controls (73.6%). There were overall 63 patients with abnormal biopsy findings in HIV group and 75 patients with abnormal biopsy findings in the control group. Among HIV positive patients who were also RUT positive approximately 80% had abnormal histopathological findings. Similarly, among the RUT positive control 81% of the patients had abnormal biopsy findings. Incidence of normal biopsy findings was more in the control group (57.1%) compared to the study group (48.4%). But this difference was not found to be statistically significant.Conclusions: The histology of gastric mucosa was no different in Helicobacter pylori positive or negative subjects with HIV. But Helicobacter pylori incidence was significantly less in HIV positive persons compared to HIV negative.

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Sero - Prevalence of <i>Helicobacter Pylori</i> in HIV Positive Patients and HIV Negative Controls in St. Paul’s General Specialized Hospital, Addis Ababa, Ethiopia

Science Journal of Public Health ◽

10.11648/j.sjph.20160405.14 ◽

2016 ◽

Vol 4 (5) ◽

pp. 387 ◽

Cited By ~ 2

Author(s):

Brhanu Teka

Keyword(s):

Helicobacter Pylori ◽

Addis Ababa ◽

Hiv Positive ◽

Specialized Hospital ◽

Negative Controls ◽

Hiv Negative

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An Observational Study of Upper Gastrointestinal Bleeding in Intensive Care Units: Is Helicobacter pylori the Culprit?

Yearbook of Critical Care Medicine ◽

10.1016/s0734-3299(08)70142-4 ◽

2006 ◽

Vol 2006 ◽

pp. 195-196

Author(s):

T. Dorman

Keyword(s):

Helicobacter Pylori ◽

Intensive Care ◽

Observational Study ◽

Gastrointestinal Bleeding ◽

Intensive Care Units ◽

Upper Gastrointestinal Bleeding ◽

Upper Gastrointestinal

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Incidence of Cytological Abnormalities in Pap's Smear in HIV Positive Women

Journal of Medical Research and Innovation ◽

10.15419/jmri.136 ◽

2018 ◽

Vol 2 (S1) ◽

pp. e000136

Author(s):

Suhana Jotva ◽

Hemani Desai ◽

Hansa Goswami

Keyword(s):

Trichomonas Vaginalis ◽

Clinical History ◽

Hiv Positive ◽

Squamous Intraepithelial Lesions ◽

Squamous Cells ◽

Medical College ◽

Hiv Positive Women ◽

Cytological Abnormalities ◽

Intraepithelial Lesions ◽

Hiv Negative

Aims and Objectives: The aim of present study is to estimate the frequency of abnormal PAP’s smears and mainly to detect precancerous and cancerous lesions as well as inflammatory lesions in HIV infected women. Methodology: Our study was a retrospective study of total 130 cases and PAP’s smears were examined in cytology section in Department of Pathology, BJ Medical College, Ahmedabad from 1st March 2017 to 31st August 2017. Both HIV positive and HIV negative patients were included in the study. 80 patients were HIV negative and 50 patients were HIV positive. The clinical history and relevant parameters were noted. All the smears were processed by a conventional method using Papanicolaou stain. Results: Out of 130 cases, 118 cases were reported negative for intraepithelial lesions or malignancy (NILM). Five cases were positive for squamous intraepithelial lesions (SIL) out of which four were HIV positive. Seven cases were of atypical squamous cells of undetermined significance (ASCUS) out of which 5 were HIV positive. Three cases were showing bacterial vaginosis. 1 case was showing Trichomonas Vaginalis. 19 cases were showing changes of non-specific inflammation. 6 cases were showing atrophic changes. Conclusion: HIV infected women are at more risk to develop cervical cytological abnormalities. The study revealed a maximum number of non-specific inflammatory smears followed by smears showing atrophic changes. Smears suspicious for malignancy (ASCUS) and smears showing squamous intraepithelial lesions (SIL) were more common in HIV positive patients. Thus regular PAP’s smears screening as recommended by National AIDS Control Organization (NACO) will help in early detection of cervical abnormalities in HIV positive women.

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