The immunohistochemical identification of hormone-producing cells in formalin-fixed, paraffin-embedded human pituitary tissue

1975 ◽  
Vol 117 (3) ◽  
pp. 163-168 ◽  
Author(s):  
A. C. Nieuwenhuyzen Kruseman ◽  
G. Th. A. M. Bots ◽  
E. Lindeman
Keyword(s):  
Human Pituitary ◽  
Pituitary Tissue ◽  
Formalin Fixed Paraffin ◽  
Formalin Fixed Paraffin Embedded ◽  
Formalin Fixed ◽  
Immunohistochemical Identification

Immunohistochemical Demonstration of Desmin in Canine Smooth Muscle Tumors

1987 ◽  
Vol 24 (3) ◽  
pp. 211-215 ◽  
Author(s):  
C. B. Andreasen ◽  
E. A. Mahaffey
Keyword(s):  
Smooth Muscle ◽  
Positive Staining ◽  
Negative Results ◽  
Formalin Fixed Paraffin ◽  
Smooth Muscle Tumors ◽  
Formalin Fixed Paraffin Embedded ◽  
Immunohistochemical Methods ◽  
Formalin Fixed ◽  
Immunohistochemical Identification ◽  
Avidin Biotin Complex

Sections of formalin-fixed, paraffin-embedded canine leiomyomas, leiomyosarcomas, or fibrosarcomas were examined by immunohistochemical methods for the presence of desmin. Twenty-two leiomyomas and leiomyosarcomas were stained using the avidin-biotin complex technique, and 14 samples demonstrated positive staining for desmin. The eight negative results obtained may reflect differences in fixation or the affinity of the primary antibody for the tissues examined. Desmin was specific for myogenic tissues. Five canine fibrosarcomas examined immunohistochemically were all negative for desmin staining. The results indicate that desmin is a useful marker for immunohistochemical identification of canine leiomyomas and leiomyosarcomas.

Sign in / Sign up

Export Citation Format

Share Document