scholarly journals Terminal sterilization: Conventional methods versus emerging cold atmospheric pressure plasma technology for non-viable biological tissues

2016 ◽  
Vol 14 (7) ◽  
pp. 1600134 ◽  
Author(s):  
Nagi M. Marsit ◽  
Laura E. Sidney ◽  
Matthew J. Branch ◽  
Samantha L. Wilson ◽  
Andrew Hopkinson
2021 ◽  
Vol 9 (2) ◽  
pp. 269-307
Author(s):  
Hom Bahadur Baniya ◽  
Rajesh Prakash Guragain ◽  
Deepak Prasad Subedi

This review summarizes the results of cold atmospheric pressure plasma technology application in polymers surface treatment. Attention is given to results of changes in the hydrophilic property of polymer surfaces by incorporation of polar functional groups when exposed to atmospheric pressure plasma, depending on the time of treatment, applied voltage, gas flow rate, and distance from the surface. We have successfully developed a plasma device that is able to generate cold atmospheric pressure argon plasma of low temperature (20 – 26) ° C downstream using a high-voltage power source which can be widely used in materials processing. Therefore, a cost-effective system of generating a plasma jet at atmospheric pressure with potential applications has been developed. Cold atmospheric pressure plasma jet (CAPPJ) has shown a lot of applications in recent years such as in materials processing, surface modification, and biomedical materials processing. CAPPJ has been generated by a high voltage (0-20 kV) and high frequency (20-30 kHz) power supply.<br/> The discharge has been characterized by optical and electrical methods. In order to characterize cold atmospheric pressure argon plasma jet, its electron density, electron temperature, rotational temperature, and vibration temperature have been determined using the power balance method, intensity ratio method, Stark broadening method, and Boltzmann plot method, respectively. The improvement in hydrophilicity of the cold plasma-treated polymer samples was characterized by contact angle measurements, surface free energy analysis, Fourier transform infrared (FTIR) spectroscopy, and scanning electron microscopy (SEM). Contact angle analysis showed that the discharge was effective in improving the wettability of polymers after the treatment. Furthermore, atmospheric plasma can be effectively used to remove surface contamination and to chemically modify different polymer surfaces. The chemical changes, especially oxidation and cross-linking, enhance the surface properties of the polymers.


Author(s):  
Kenneth A. Cornell ◽  
Amanda White ◽  
Adam Croteau ◽  
Jessica Carlson ◽  
Zeke Kennedy ◽  
...  

2011 ◽  
Vol 109 (12) ◽  
pp. 123302 ◽  
Author(s):  
J. S. Sousa ◽  
K. Niemi ◽  
L. J. Cox ◽  
Q. Th. Algwari ◽  
T. Gans ◽  
...  

2013 ◽  
Vol 647 ◽  
pp. 524-531
Author(s):  
Vinita Sharma ◽  
Katsuhiko Hosoi ◽  
Tamio Mori ◽  
Shin-ichi Kuroda

In this study, we conducted experiments to investigate the effectiveness of a non-equilibrium Ar-N2 plasma jet generated by a Cold Atmospheric Pressure Plasma Torch (CAPPLAT) at a sinusoidal voltage of 20 kV, frequency of 30 kHz with 10 slm of Ar gas and 100 sccm of N2 gas. Highly environmental stress resistant bacterial endospores of Bacillus subtilis, dried on an agar disc were exposed to the plasma discharge from the CAPPLAT for different durations. The viability of spores after plasma exposure was checked by counting CFUs by serial dilution method. We also measured the amount of released DPA (dipicolinic acid, pyridine-2, 6-dicarboxylic acid), which is exclusively found in endospore protoplast (cortex), to confirm the disintegration of the cortex. We could successfully inactivate a population of Bacillus endospores of about 1.0 × 107 to 4.0 × 107 spores/ml.


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