Inhibitory effects of the sesquiterpene T-cadinol on contractile responses in the isolated guinea-pig ileum

1991 ◽  
Vol 5 (3) ◽  
pp. 142-144 ◽  
Author(s):  
Peter Zygmunt ◽  
Per Claeson
Keyword(s):  
Guinea Pig ◽  
Inhibitory Effects ◽  
Guinea Pig Ileum ◽  
Contractile Responses

Inhibitory effects of quercetin on guinea-pig ileum contractions

1996 ◽  
Vol 10 (1) ◽  
pp. 66-69 ◽  
Author(s):  
J. Gálvez ◽  
J. Duarte ◽  
F. Sánchez de Medina ◽  
J. Jiménez ◽  
A. Zarzuelo
Keyword(s):  
Guinea Pig ◽  
Inhibitory Effects ◽  
Guinea Pig Ileum

scholarly journals Inhibitory effects of paraquat on guinea pig ileum contraction

1997 ◽  
Vol 73 ◽  
pp. 105
Author(s):  
Joji Tomioka ◽  
Shinichiro Suzaki ◽  
Akira Kurokawa ◽  
Yasuhiro Yamamoto ◽  
Toshibumi Oluka ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Inhibitory Effects ◽  
Guinea Pig Ileum ◽  
Ileum Contraction

scholarly journals Effect of tripropylsulfonium bromide on the contractile responses of the isolated guinea-pig ileum to some agonists

1990 ◽  
Vol 52 ◽  
pp. 352
Author(s):  
Shozo Takamura ◽  
Junko Yoshida ◽  
Shiro Suzuki ◽  
Fumihisa Miyoshi ◽  
Kenji Tokuno ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Guinea Pig Ileum ◽  
Contractile Responses

A comparison of the inhibitory effects of somatostatin-14, -25, and -28 on motility of the guinea pig ileum

1986 ◽  
Vol 64 (3) ◽  
pp. 303-306 ◽  
Author(s):  
Christopher H. S. McIntosh ◽  
Victoria Bakich ◽  
Yin Nam Kwok ◽  
John C. Brown
Keyword(s):  
Biological Activity ◽  
Amino Acid ◽  
Guinea Pig ◽  
Biological Activities ◽  
Threshold Concentration ◽  
Inhibitory Effects ◽  
Guinea Pig Ileum ◽  
Maximal Inhibition ◽  
Acid Fragment ◽  
Somatostatin 14

A number of studies have suggested that somatostatin-14 (SS-14) and somatostatin-28 (SS-28) exhibit a similar spectrum of biological activities but have different potencies. In the present study the effects of SS-14, SS-28, and somatostatin-25 on electrically induced contractions of the guinea pig ileum have been compared. All three peptides exhibited equipotent inhibitory effects. Inhibition was obtained at a threshold concentration less than 10−10 M, with maximal inhibition at 10−7 M and IC50 values of 6.0–6.5 × 10−10 M. The N-terminal 14 amino acid fragment of SS-28 had no effect either on motility, when added alone, or on the actions of SS-28, suggesting that this region of the molecule is not critical for biological activity.

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