Application of open port sampling interface mass spectrometry (OPSI‐MS) to deuterium exchange as an aid for structural elucidation

2020 ◽  
Author(s):  
Andrew D. Ray ◽  
Graeme Clemens ◽  
Stephen W. Holman
Keyword(s):  
Mass Spectrometry ◽  
Structural Elucidation ◽  
Deuterium Exchange ◽  
Sampling Interface ◽  
Open Port

Open port sampling interface mass spectrometry of wipe-based explosives, oxidizers, and narcotics for trace contraband detection

2021 ◽  
Author(s):  
Thomas P Forbes ◽  
Jeffrey Lawrence ◽  
Changtong Hao ◽  
Greg Gillen
Keyword(s):  
Mass Spectrometry ◽  
Law Enforcement ◽  
Physicochemical Properties ◽  
Homeland Security ◽  
Rapid Screening ◽  
Organic P ◽  
Sampling Interface ◽  
Open Port

Rapid screening for chemical traces of explosives and narcotics is widely used to support homeland security and law enforcement. These target compounds span a range of physicochemical properties from organic...

scholarly journals Combined Falling Drop/Open Port Sampling Interface System for Automated Flow Injection Mass Spectrometry

2017 ◽  
Vol 89 (22) ◽  
pp. 12578-12586 ◽  
Author(s):  
Gary J. Van Berkel ◽  
Vilmos Kertesz ◽  
Matt Orcutt ◽  
Adam Bentley ◽  
Jim Glick ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Flow Injection ◽  
Interface System ◽  
Sampling Interface ◽  
Open Port

scholarly journals Fast quantitation of opioid isomers in human plasma by differential mobility spectrometry/mass spectrometry via SPME/open-port probe sampling interface

2017 ◽  
Vol 991 ◽  
pp. 89-94 ◽  
Author(s):  
Chang Liu ◽  
Germán Augusto Gómez-Ríos ◽  
Bradley B. Schneider ◽  
J.C.Yves Le Blanc ◽  
Nathaly Reyes-Garcés ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Human Plasma ◽  
Differential Mobility Spectrometry ◽  
Differential Mobility ◽  
Sampling Interface ◽  
Open Port

scholarly journals Immediate drop on demand technology (I-DOT) coupled with mass spectrometry via an open port sampling interface

Bioanalysis ◽  
2017 ◽  
Vol 9 (21) ◽  
pp. 1667-1679 ◽  
Author(s):  
Gary J Van Berkel ◽  
Vilmos Kertesz ◽  
Harry Boeltz
Keyword(s):  
Mass Spectrometry ◽  
On Demand ◽  
Drop On Demand ◽  
Sampling Interface ◽  
Open Port

Detection, Identification and Structural Elucidation of Flavonoids using Liquid Chromatography Coupled to Mass Spectrometry

2020 ◽  
Vol 24 (1) ◽  
pp. 104-112 ◽  
Author(s):  
Krzysztof Kamil Wojtanowski ◽  
Tomasz Mroczek
Keyword(s):  
Mass Spectrometry ◽  
Central Nervous System ◽  
Nuclear Magnetic Resonance ◽  
Liquid Chromatography ◽  
High Performance ◽  
Short Review ◽  
Structural Elucidation ◽  
High Throughput Analysis ◽  
Protective Actions ◽  
The Central Nervous System

Flavonoids are one of the most common secondary metabolites occurring in plants. Their activity in the Central Nervous System (CNS) including sedative, anxiolytic, anti-convulsive, anti-depressant and neuro-protective actions is well known and documented. The most popular methods for detection, identification and structural elucidation of flavonoids are these based on Nuclear Magnetic Resonance (NMR) and mass spectrometry (MS). NMR allows rapid, high throughput analysis of crude extracts and also gives stereochemical details about identified substances. However, these methods are expensive and less sensitive than MS-based techniques. Combining High Performance Liquid Chromatography (HPLC) with MS detection gives the most powerful tool for analysis of flavonoids occurring in plants. There is a lot of different approaches to use LC/MS based techniques for identification of flavonoids and this short review shows the most important.

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