Effect of dietary selenium deficiency on the in vitro fertilizing ability of mice spermatozoa

2007 ◽  
pp. 41-49 ◽  
Author(s):  
M. Sánchez-Gutiérrez ◽  
E. A. García-Montalvo ◽  
J. A. Izquierdo-Vega ◽  
L. M. Del Razo
Keyword(s):  
Selenium Deficiency ◽  
Dietary Selenium ◽  
Fertilizing Ability

scholarly journals Effect of dietary selenium deficiency on the in vitro fertilizing ability of mice spermatozoa

2007 ◽  
Vol 24 (4) ◽  
pp. 321-329 ◽  
Author(s):  
M. Sánchez-Gutiérrez ◽  
E. A. García-Montalvo ◽  
J. A. Izquierdo-Vega ◽  
L. M. Del Razo
Keyword(s):  
Selenium Deficiency ◽  
Dietary Selenium ◽  
Fertilizing Ability

scholarly journals Inhibition of hepatic deiodination of thyroxine is caused by selenium deficiency in rats

1987 ◽  
Vol 248 (2) ◽  
pp. 443-447 ◽  
Author(s):  
G J Beckett ◽  
S E Beddows ◽  
P C Morrice ◽  
F Nicol ◽  
J R Arthur
Keyword(s):  
Thyroid Hormones ◽  
Production Rate ◽  
Selenium Deficiency ◽  
Enzyme Complex ◽  
Measurable Effect ◽  
Direct Role ◽  
Mechanism Of Inhibition ◽  
Se Deficiency

Selenium (Se) deficiency produced up to a 14-fold decrease in hepatic tri-iodothyronine (T3) production from thyroxine (T4) in vitro. The T3 production rate could not be restored by the addition of a variety of cofactors, nor by the addition of control homogenate. The impairment in hepatic T3 production observed in Se deficiency was reflected in the concentrations of thyroid hormones circulating in plasma, T4 being increased approx. 40% and T3 being decreased by 30%. However, the fall in plasma T3 concentrations was smaller than might be expected in view of the marked decreased in T3 production. Se deficiency had no measurable effect on plasma reverse-tri-iodothyronine concentrations. The data suggest that Se deficiency produces an inhibition of both 5- and 5′-deiodination, consistent with the widely held view that these reactions are catalysed by the same enzyme complex. The mechanism of inhibition appears not be mediated by changes in thiol levels, but a direct role of Se in the activity of the deiodinase complex cannot be excluded.

scholarly journals Dietary Selenium Deficiency Exacerbates DSS-Induced Epithelial Injury and AOM/DSS-Induced Tumorigenesis

PLoS ONE ◽  
2013 ◽  
Vol 8 (7) ◽  
pp. e67845 ◽  
Author(s):  
Caitlyn W. Barrett ◽  
Kshipra Singh ◽  
Amy K. Motley ◽  
Mary K. Lintel ◽  
Elena Matafonova ◽  
...  
Keyword(s):  
Selenium Deficiency ◽  
Epithelial Injury ◽  
Dietary Selenium

scholarly journals Impaired Fertilizing Ability of Superoxide Dismutase 1-Deficient Mouse Sperm During In Vitro Fertilization1

2012 ◽  
Vol 87 (5) ◽  
Author(s):  
Satoshi Tsunoda ◽  
Natsuko Kawano ◽  
Kenji Miyado ◽  
Naoko Kimura ◽  
Junichi Fujii
Keyword(s):  
Superoxide Dismutase ◽  
Deficient Mouse ◽  
Superoxide Dismutase 1 ◽  
Mouse Sperm ◽  
Fertilizing Ability

Effect of oviductal secretions and cells on fertilizing ability of goat spermatozoa in vitro

1997 ◽  
Vol 47 (1) ◽  
pp. 331 ◽  
Author(s):  
P. Barahona ◽  
F. Saravia ◽  
A.Santa María ◽  
M. Briones ◽  
J.F. Cox
Keyword(s):  
Fertilizing Ability

scholarly journals Biological effects of polyphenol-rich extract and fractions from an oenological oak-derived tannin on in vitro swine sperm capacitation and fertilizing ability

2018 ◽  
Vol 108 ◽  
pp. 284-290 ◽  
Author(s):  
Marcella Spinaci ◽  
Vera Muccilli ◽  
Diego Bucci ◽  
Nunzio Cardullo ◽  
Beatrice Gadani ◽  
...  
Keyword(s):  
Biological Effects ◽  
Sperm Capacitation ◽  
Fertilizing Ability

MiR-196-5p involvement in selenium deficiency-induced immune damage via targeting of NFκBIA in the chicken trachea

Metallomics ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 1679-1692 ◽  
Author(s):  
Linqian Qin ◽  
Yiming Zhang ◽  
Chunyan Wan ◽  
Zhu Wang ◽  
Yimei Cong ◽  
...  
Keyword(s):  
Selenium Deficiency ◽  
Dietary Selenium ◽  
Immune Injury ◽  
Se Deficiency

Dietary selenium (Se) deficiency can induce multifarious immune injury in tissues, accompanied by inflammation and a decreased expression of selenoproteins.

303 FERTILIZATION-RELATED PARAMETERS OF FROZEN - THAWED SPERMATOZOA FROM SUBFERTILE JAPANESE BLACK CATTLE

2007 ◽  
Vol 19 (1) ◽  
pp. 266
Author(s):  
K. Kuroda ◽  
M. Fukushima ◽  
M. Miyake ◽  
H. Harayama
Keyword(s):  
Acrosome Reaction ◽  
Economic Losses ◽  
Japanese Black Cattle ◽  
Cell Stage ◽  
Causal Factors ◽  
Mean Values ◽  
Progressive Movement ◽  
Male Subfertility ◽  
Fertilizing Ability

The subfertility derived from male factors is a problem of concern in domestic animals, because it could cause a disintegration of the breeding system and large economic losses, particularly when the subfertility affects genetically superior male animals. Therefore, it is urgent that causal factors of male subfertility be determined. Recently, an increasing number of subfertile bulls have been found among Japanese Black cattle, which is a representative breed of Japanese beef cattle. The purpose of the present study was to elucidate causal factors of male subfertility in Japanese Black cattle. Frozen–thawed spermatozoa from 8 subfertile (S1-S8) and 7 fertile (F1–F7, control) bulls were used for the assessment of fertilization-related parameters. The data obtained from each subfertile bull in the following experiments were individually compared with the mean values of the fertile bull group. In Experiment 1, sperm motility was observed in samples that were frozen-thawed and subsequently washed in PBS. Many spermatozoa (higher than 65%) exhibited flagellar movement in all samples from fertile and subfertile bulls. However, the percentages of progressively motile spermatozoa from 2 subfertile bulls were significantly lower (S2: 6%; S7: 7%; P < 0.05, ANOVA and Tukey's multiple range tests) than those from fertile bulls (average: 37%). Moreover, rapidly progressive movement was not observed in the spermatozoa from 4 subfertile bulls (S1, S2, S6, and S7). These data suggest abnormality in the motility system of sperm flagella in these 4 subfertile bulls. In Experiment 2, the capacitation–acrosome reaction state of frozen–thawed spermatozoa was examined by the CTC-staining assay. More than 50% of the frozen–thawed spermatozoa from 4 subfertile bulls (S5–S8) were prematurely progressing in the capacitation state immediately after washing and resuspension in the medium lacking CaCl2. Moreover, the addition of CaCl2 to the medium induced acrosomal loss in these sperm samples (percentages of spermatozoa without the acrosome: 36–49%). These findings indicate the occurrence of premature capacitation and a spontaneous acrosome reaction in spermatozoa from these 4 subfertile bulls. In Experiment 3, the in vitro fertilizing ability of frozen–thawed spermatozoa was evaluated by the IVF test. The percentages of fertilized eggs with both male and female pronuclei or developmental rates of fertilized eggs to the 2-cell or 4-cell stage were significantly lower in the spermatozoa from S6 to S8 bulls than in those from fertile bulls (P < 0.05, chi-squared tests). This may suggest that spermatozoa from these 3 subfertile bulls hardly accomplish the normal fertilization process. In summary, low progressive motility and low in vitro fertilizing ability because of premature capacitation were found in the spermatozoa from subfertile bulls. It is therefore possible that these are causal factors for the subfertility of male Japanese Black cattle.

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