Gas Chromatographic Method for the Determination of Testosterone in Human Urine

Author(s):  
Walter Futterweit ◽  
George L. Siegel ◽  
Ruth Freeman ◽  
Solomon I. Griboff ◽  
Michael Drosdowsky ◽  
...  
1965 ◽  
Vol 49 (4) ◽  
pp. 553-557 ◽  
Author(s):  
Michael A. Drosdowsky ◽  
Athanasios Dessypris ◽  
Neal L. McNiven ◽  
Ralph I. Dorfman ◽  
Carlos Gual

ABSTRACT The determination of testosterone in urine provides an easier means for the appreciation of androgenicity than plasma analysis. On this basis a search for progesterone in urine was made without success. Progesterone could not be detected by the gas chromatographic method used. This negative result was confirmed when progesterone-4-14C was injected intravenously and neither radioactive progesterone nor labelled 20α-hydroxy-pregn-4-en-3-one and/or 20β-hydroxy-pregn-4-en-3-one could be detected in the urine.


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