Urothelial Cell Carcinoma in Lower Urinary Tract: Conventional Imaging Techniques

2008 ◽  
pp. 177-184
Author(s):  
C.Y. Nio
Keyword(s):  
Urinary Tract ◽  
Cell Carcinoma ◽  
Lower Urinary Tract ◽  
Imaging Techniques ◽  
Urothelial Cell ◽  
Conventional Imaging ◽  
Urothelial Cell Carcinoma ◽  
Lower Urinary

Contemporary evaluation of urography in diagnosis in patients with urothelial cell carcinoma.

2013 ◽  
Vol 31 (6_suppl) ◽  
pp. 312-312
Author(s):  
Anna Maria Leliveld ◽  
Benjamin HJ Doornweerd ◽  
Igle De Jong
Keyword(s):  
Urinary Tract ◽  
Cell Carcinoma ◽  
Imaging Techniques ◽  
Medical Center ◽  
Upper Urinary Tract ◽  
Urothelial Cell ◽  
Urothelial Cell Carcinoma ◽  
Muscle Invasive ◽  
The University

312 Background: Upper urinary tract tumors (UUTT) can occur synchronous or metachronous (0.7 – 6%) with bladder tumors. The optimal imaging technique of the upper urinary tract is unclear. Studies on the accuracy of retrograde pyelography (RUP) and comparative studies on detection level are sparse. In this study we evaluated the effectiveness of a first RUP in patients with a first manifestation of urothelial cell carcinoma (UCC) in the urinary tract. Methods: In this retrospective study we evaluated all consecutive patients with pathologic proven UCC who underwent their first RUP between March 1998 and April 2008 in the University Medical Center Groningen, Netherlands. Data regarding patient and tumor characteristics, results from RUPs, use of alternative imaging techniques, treatment and outcome were collected from the electronically patient’s records. Follow up was calculated from the first RUP to the last registrated visit. Descriptive statistics have been used to evaluate the performance of the RUP. Results: A total of 156 patients underwent a first RUP because of a first manifestation of UCC of the bladder or upper urinary tract. A mean follow up of 5.09 years was achieved (range 0-13 years). On 17 RUPs (11%) abnormalities were detected. In 16 patients a malignancy was diagnosed. Except one renal cell carcinoma all tumors were UCC of the renal pelvis, ureters or both. Muscle invasive tumors were diagnosed in 7 of these 17 patients. In 30 patients (19%) no conclusive results were obtained because of failure of the RUP due to technical difficulties. In 19 of 30 patients alternative imaging was performed, with intravenous pyelography in 11 patients, computer tomography urography in 7 patients and with both in 1 patient. No UUTTs were diagnosed in this group. In 109 (70%) patients whit a negative RUP three patients developed a tumor after 8, 52, and 65 months. The latter two we consider as newly developed lesions. Conclusions: RUP in patients with a first manifestation of UCC is a very sensitive and accurate diagnostic tool in detecting UUTT.

scholarly journals Prostatic basal cell carcinoma treated by chemoradiation with weekly cisplatine: case report and literature review

2021 ◽  
Vol 27 (1) ◽  
Author(s):  
S. Ridai ◽  
C. Moustakbal ◽  
A. Lachgar ◽  
H. Jouhadi ◽  
A. Benider ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Urinary Tract ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Lower Urinary Tract Symptoms ◽  
Basal Cell ◽  
Lower Urinary Tract ◽  
Locally Advanced ◽  
Urinary Tract Symptoms ◽  
Lower Urinary

Abstract Background Basal cell carcinoma of the prostate is a relatively rare entity. Their evolution is characterized by the frequency of local and/or distant relapses. Due to their rarity, the treatment is not consensual in the literature. We report here a case of Basal cell carcinoma of the prostate in a 40-year-old patient. Case presentation Our patient initially presented an obstructive lower urinary tract symptoms with a normal initial level of prostate specific antigen (PSA) test (3.5 ng/m). The transurethral resection of the prostate (TURP) was in favor of a prostatic basal cell carcinoma with its specific anatomopathological and immunohistochemical characteristics. The prostatic MRI and thoraco-abdominal CT realized after the TURP revealed a tumoral lesion of the prostatic peripheral zone with extra-capsular extension combined with right seminal vesicle invasion and a suggestion of posterior bladder wall adherence. No evidence of visceral or nodal metastases at this point. Considering the tumor being locally advanced, a concurrent chemoradiotherapy with intensity modulated technique was indicated after a multidisciplinary meeting with a 70 Gy total target dose delivered in 35 fractions and weekly Cisplatin. A year and a half after, he developed a cerebellous metastases revealed by intracranial hypertension with no other visceral lesion and complete local remission with the disappearance of the lower urinary tract symptoms and the pain and the appearance of a prostatic atrophy. The PSA level was still on the upper limit of normal. He underwent metastasectomy, and the anatomopathological study was in favor of a cerebellous metastasis of the known BCC. The patient presented postoperatively paraparesis of lower limbs with balance problems for which he was placed in palliative care with indication of postoperative radiation therapy in case of improvement of his general condition. He did not recover and deceased three months later. Conclusions The prostatic basal cell carcinoma is a rare aggressive entity often non-evoked at the clinical or radiological stages because of its unspecific appearance. The diagnostic of these tumors is based on histological examination and a large immunohistochemistry panel. Given its scarity, very few data is available for locally advanced non-metastatic stages treated by radiation therapy. We assess here a good local response with concurrent chemoradiation therapy.

Genitourinary cancers

2016 ◽  
pp. 602-627
Author(s):  
John Fitzpatrick ◽  
Asif Muneer ◽  
Jean de la Rosette ◽  
Thomas Powles
Keyword(s):  
Urinary Tract ◽  
Cell Carcinoma ◽  
Penile Cancer ◽  
Surgical Techniques ◽  
Upper Urinary Tract ◽  
Urothelial Cell ◽  
Urothelial Cell Carcinoma ◽  
Von Hippel Lindau ◽  
Genitourinary Cancers ◽  
Rare Malignancy

Genitourinary cancers include tumors of the penis, bladder, prostate, testes, kidneys and ureters. Penile cancer is a rare malignancy and the diagnosis is often delayed due to patient embarrassment. Penile-preserving surgical techniques have been developed to preserve penile length. Urothelial cell carcinoma is more often encountered in bladder (95%) than in the upper urinary tract (5%). This chapter will be divided according to the two main urothelial cell carcinoma topographies: bladder and upper urinary tract. Prostate cancer is second as far as cause of cancer death is concerned, and surgical, radiotherapeutic and hormonal treatments are discussed. Most testicular cancers that arise are germ cell tumours. Renal cell carcinoma has a number of distinct pathological types. The commonest is clear cell histology which is intrinsically linked to Von Hippel-Lindau (VHL) mutations. New targeted therapies for renal carcinomas will be described in detail.

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