Evaluation of Osteosynthesis Options and Fracture Healing Progress from Computed Tomography Based Finite Element Analysis

Author(s):  
J. Koerber ◽  
S. Eberle ◽  
P. Augat
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Graeme R. Paul ◽  
Esther Wehrle ◽  
Duncan C. Tourolle ◽  
Gisela A. Kuhn ◽  
Ralph Müller

AbstractMechanical loading allows both investigation into the mechano-regulation of fracture healing as well as interventions to improve fracture-healing outcomes such as delayed healing or non-unions. However, loading is seldom individualised or even targeted to an effective mechanical stimulus level within the bone tissue. In this study, we use micro-finite element analysis to demonstrate the result of using a constant loading assumption for all mouse femurs in a given group. We then contrast this with the application of an adaptive loading approach, denoted real time Finite Element adaptation, in which micro-computed tomography images provide the basis for micro-FE based simulations and the resulting strains are manipulated and targeted to a reference distribution. Using this approach, we demonstrate that individualised femoral loading leads to a better-specified strain distribution and lower variance in tissue mechanical stimulus across all mice, both longitudinally and cross-sectionally, while making sure that no overloading is occurring leading to refracture of the femur bones.


2018 ◽  
Vol 46 (8) ◽  
pp. 1112-1127 ◽  
Author(s):  
Fanwei Kong ◽  
Thuy Pham ◽  
Caitlin Martin ◽  
Raymond McKay ◽  
Charles Primiano ◽  
...  

Author(s):  
Catalina Farcasiu ◽  
Rodica Luca ◽  
Alexandru-Titus Farcasiu ◽  
Aneta Munteanu ◽  
Oana-Cella Andrei

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