This chapter poses the question of “reality”. In opposition to a substantialist vision that has notably characterized modernity, Whitehead develops a processual conception of the real which is made of becomings and individuations. This vision of the real is envisaged starting from three distinct questions: First of all, how to exactly define a process of individuation? This question is treated in its historical aspects (Aristotle and Leibniz) and with respect to contemporary philosophy (Simondon and Deleuze). Secondly, where do the forms, the puissances, the virtualities derive from which accompany any individuation? Starting from this question it is most notably the relation with Platonism and its heritage that is elaborated. And third, which vision of time is implied in a theory of individuation? Even though close to Bergson, Whitehead’s philosophy profoundly differs from it with respect to the status of time and builds up new links with contemporary science.