An experimental study of mucociliary pathology of the eustachian tube in otitis media with effusion induced by irradiation

1989 ◽  
Vol 246 (6) ◽  
pp. 428-432 ◽  
Author(s):  
Y. Ohashi ◽  
Y. Nakai ◽  
Y. Esaki ◽  
Y. Onoyama
Keyword(s):  
Experimental Study ◽  
Otitis Media ◽  
Eustachian Tube ◽  
Otitis Media With Effusion

Relation between Nasal and Middle Ear Allergy Experimental Study

1980 ◽  
Vol 89 (3_suppl) ◽  
pp. 147-152 ◽  
Author(s):  
Toshio Yamashita ◽  
Nobuhiro Okazaki ◽  
Tadami Kumazawa
Keyword(s):  
Experimental Study ◽  
Otitis Media ◽  
Eustachian Tube ◽  
Middle Ear ◽  
Guinea Pigs ◽  
Otitis Media With Effusion ◽  
The Other ◽  
Nasal Allergy ◽  
Tympanic Cavity ◽  
Direct Relation

This study was undertaken to clarify the relation between nasal allergy and otitis media with effusion and to observe histologically the allergic changes in the eustachian tube itself in animals. Allergic changes in the eustachian tube and tympanic cavity were clearly observed histologically when the antigen had been introduced into the tympanic cavity of sensitized guinea pigs. On the other hand, administration of the antigen into the nose produced marked allergic changes in the nose and pharynx but no change in the eustachian tube or tympanic cavity. In view of these findings, it is suggested that allergy of the nose bears little direct relation to that of the middle ear and the eustachian tube.

Relationship between Eustachian tube dysfunction and otitis media with effusion in radiotherapy patients

2018 ◽  
Vol 132 (2) ◽  
pp. 111-116 ◽  
Author(s):  
K Akazawa ◽  
H Doi ◽  
S Ohta ◽  
T Terada ◽  
M Fujiwara ◽  
...  
Keyword(s):  
Radiation Dose ◽  
Otitis Media ◽  
Eustachian Tube ◽  
Otitis Media With Effusion ◽  
Intensity Modulated Radiotherapy ◽  
Eustachian Tube Dysfunction ◽  
Dose Volume ◽  
Tube Dysfunction ◽  
The Relationship ◽  
Higher Doses

AbstractObjective:This study evaluated the relationship between radiation and Eustachian tube dysfunction, and examined the radiation dose required to induce otitis media with effusion.Methods:The function of 36 Eustachian tubes in 18 patients with head and neck cancer were examined sonotubometrically before, during, and 1, 2 and 3 months after, intensity-modulated radiotherapy. Patients with an increase of 5 dB or less in sound pressure level (dB) during swallowing were categorised as being in the dysfunction group. Additionally, radiation dose distributions were assessed in all Eustachian tubes using three dose–volume histogram parameters.Results:Twenty-two of 25 normally functioning Eustachian tubes before radiotherapy (88.0 per cent) shifted to the dysfunction group after therapy. All ears that developed otitis media with effusion belonged to the dysfunction group. The radiation dose threshold evaluation revealed that ears with otitis media with effusion received significantly higher doses to the Eustachian tubes.Conclusion:The results indicate a relationship between radiation dose and Eustachian tube dysfunction and otitis media with effusion.

scholarly journals Otitis media with effusion in adults with patulous Eustachian tube

2019 ◽  
Vol 48 (2) ◽  
pp. 030006051987538
Author(s):  
Tao Fu ◽  
Caili Ji ◽  
Zhiyuan Wang ◽  
Xiaowen Zhang ◽  
Min Zhang ◽  
...  
Keyword(s):  
Gastroesophageal Reflux ◽  
Otitis Media ◽  
Eustachian Tube ◽  
Otitis Media With Effusion ◽  
Duration Of Disease ◽  
Patulous Eustachian Tube

Highlight 1.  Patients with patulous Eustachian tube (PET) were older, had a shorter duration of disease, and were more likely to develop bilateral otitis media with effusion. 2. Patients with PET were more likely to develop comorbidities of gastroesophageal reflux and allergies.

Tympanograms Of Otitis Media With Effusion: An Experimental Study

1985 ◽  
Vol 12 ◽  
pp. S222-S224 ◽  
Author(s):  
Takuji Okitsu ◽  
Toshimitsu Kobayashi ◽  
Satomi Endo ◽  
Yoshihiro Shibahara ◽  
Mayumi Sakuma ◽  
...  
Keyword(s):  
Experimental Study ◽  
Otitis Media ◽  
Otitis Media With Effusion

Role of Ige-Mediated Hypersensitivity in Otitis Media with Effusion: Pathophysiologic Considerations

1994 ◽  
Vol 103 (5_suppl) ◽  
pp. 15-19 ◽  
Author(s):  
Joel M. Bernstein ◽  
William J. Doyle
Keyword(s):  
Otitis Media ◽  
Eustachian Tube ◽  
Middle Ear ◽  
Otitis Media With Effusion ◽  
Chronic Otitis Media ◽  
Accessory Cell ◽  
Middle Ear Mucosa ◽  
Mucus Production ◽  
Mediators Of Inflammation ◽  
Ige Mediated

A pathophysiologic model of otitis media with effusion secondary to IgE-mediated hypersensitivity is described. Specific mediators of inflammation are released by mucosal mast cells in the nasal mucosa following the interaction of antigen and specific IgE antibody. These mediators increase vascular permeability, mucosal blood flow, and, most important, mucus production. Furthermore, accessory cell types are recruited by colony-stimulating factors that in turn provide an autocrine-positive feedback for the influx of further inflammatory cells. The eustachian tube is then effectively obstructed by both intrinsic venous engorgement and extrinsic mucus plugs, isolating the middle ear space from the ambient environment The net result is the increased exchange of nitrogen into the middle ear mucosa from the middle ear cavity. This causes the development of a significant middle ear underpressure that disrupts tight junctions and allows for transudation of fluids into the middle ear space. The prolonged obstruction of the eustachian tube with mucus results in middle ear inflammation, mucosal metaplasia, and increased glandular activities, all of which are hallmarks of chronic otitis media with effusion.

Effect of Oxatomide on Otitis Media with Effusion—An Experimental Study

1995 ◽  
Vol 115 (4) ◽  
pp. 532-538 ◽  
Author(s):  
Takahiro Tanaka ◽  
Yuichi Kurono ◽  
Hideyuki Kawauchi ◽  
Goro Mogi
Keyword(s):  
Experimental Study ◽  
Otitis Media ◽  
Otitis Media With Effusion
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