Reaction of ethoxyvinyl derivatives of pyrylium and pyridinium salts with primary and secondary amines

1974 ◽  
Vol 10 (10) ◽  
pp. 1166-1171 ◽  
Author(s):  
G. N. Dorofeenko ◽  
V. V. Mezheritskii ◽  
A. L. Vasserman
Keyword(s):  
Secondary Amines ◽  
Pyridinium Salts ◽  
Primary And Secondary Amines ◽  
Derivatives Of

Some 1-substitution derivatives of 4-aryl-2,3-dihalogeno-1-naphthols

1984 ◽  
Vol 49 (1) ◽  
pp. 110-121 ◽  
Author(s):  
Jiří Křepelka ◽  
Drahuše Vlčková ◽  
Milan Mělka
Keyword(s):  
Thionyl Chloride ◽  
Oxirane Ring ◽  
Secondary Amines ◽  
Two Phase ◽  
Lytic Effect ◽  
Primary And Secondary Amines ◽  
Phase Medium ◽  
Chloro Derivatives ◽  
Derivatives Of

Alkylation of derivatives of 4-aryl-1-naphthols (I-V) by 2,3-epoxypropyl chloride in methanolic sodium hydroxide gave epoxy derivatives VI, VIII, IX, XI and XII, apart from products of cleavage of the oxirane ring, VII and X. Analogous alkylation of compounds I, IV and V by 2-(N,N-diethylamino)ethyl chloride hydrochloride in a two-phase medium afforded basic ethers XIII to XV. The cleavage of the oxirane ring in compound VI by the action of primary and secondary amines, piperidine and substituted piperazines led to compounds XVI-XXIV. Reaction of thionyl chloride with compounds XXI, XXII and XXIV gave chloro derivatives XXV-XXVII.Exposure of compound XXII to 4-methylbenzenesulfonyl chloride produced compound XXVIII, retaining the secondary alcoholic group. In an antineoplastic screening in vivo none of the compounds prepared had an appreciable activity. Compound XVII, being an analogue of propranolol, was used in the test of isoproterenolic tachycardia, and showed a beta-lytic effect comparable with that of propranol.

Liquid Chromatographic Determination of Primary and Secondary Amines as 8-Quinolinesulfonyl Chloride Derivatives

1984 ◽  
Vol 67 (4) ◽  
pp. 687-691
Author(s):  
F Taylor Noggle ◽  
C Randall Clark
Keyword(s):  
Chromatographic Determination ◽  
Secondary Amines ◽  
Absorption Bands ◽  
Reverse Phase ◽  
Primary And Secondary Amines ◽  
Liquid Chromatographic Determination ◽  
Phase Liquid ◽  
Liquid Chromatographic ◽  
Derivatives Of

Abstract The normal phase and reverse phase liquid chromatographic properties of seven 8-quinolinesulfonyl derivatives of primary and secondary amines are examined using dual wavelength ultraviolet detection. The amines are further identified by infrared spectrophotometry with emphasis on structural elucidation based on absorption bands at characteristic wavelengths.

Enhanced Detectability and Chromatography of Some Amines by High Pressure Liquid Chromatography

1980 ◽  
Vol 63 (4) ◽  
pp. 702-706
Author(s):  
F Taylor Noggle
Keyword(s):  
High Pressure ◽  
Liquid Chromatography ◽  
High Pressure Liquid Chromatography ◽  
Secondary Amines ◽  
High Pressure Liquid Chromatographic ◽  
Ultraviolet Detection ◽  
Primary And Secondary Amines ◽  
Liquid Chromatographic ◽  
Derivatives Of

Abstract The high pressure liquid chromatographic properties of 13 phenylisothiocyanate derivatives of primary and secondary amines were examined with ultraviolet detection at 254 nm. Urine extracts of subjects who were taking ephedrine, phenylpropanolamine, and phentermine were also examined. The method described improves the chromatographic properties of the amines and also enhances their detectability.

scholarly journals Reductive amination of fusidane triterpenoid ketones

2018 ◽  
Vol 7 (3) ◽  
pp. 198-203 ◽  
Author(s):  
Elena Salimova ◽  
Andrey Mamaev ◽  
Elena Tretyakova ◽  
Olga Kukovinets ◽  
Lyudmila Parfenova
Keyword(s):  
Methyl Ester ◽  
Fusidic Acid ◽  
Reductive Amination ◽  
Secondary Amines ◽  
Primary And Secondary Amines ◽  
Reaction Proceeds ◽  
Derivatives Of

New nitrogen-containing analogues of fusidane triterpenoids were synthesized via the reductive amination of 3,11-dioxo derivatives of fusidic acid and its methyl ester by primary and secondary amines (BunNH2, Pyrrolidine, NH2CH2CH2NH2) in the presence of sodium borohydrides. The reaction proceeds with high chemo- and stereoselectivity and gives 3β-amino substituted products with yields of 75-88%.

Reaction of arylmethylenemalonaldehydes with some nucleophiles

1987 ◽  
Vol 52 (11) ◽  
pp. 2699-2709 ◽  
Author(s):  
Dalimil Dvořák ◽  
Zdeněk Arnold
Keyword(s):  
Inorganic Anions ◽  
Secondary Amines ◽  
Tertiary Amines ◽  
Primary And Secondary Amines ◽  
Dipolar Structure

Reaction of arylmethylenemalonaldehydes with tributylphosphine and tertiary amines affords compounds of dipolar structure whereas reaction with primary and secondary amines leads to 1,4-addition products. Salts of nucleophilic inorganic anions add to arylmethylenemalonaldehydes under formation of salts of substituted malonaldehydes.

ChemInform Abstract: Continuous-Flow Oxidative Cyanation of Primary and Secondary Amines Using Singlet Oxygen.

ChemInform ◽  
2014 ◽  
Vol 45 (30) ◽  
pp. no-no
Author(s):  
Dmitry B. Ushakov ◽  
Kerry Gilmore ◽  
Daniel Kopetzki ◽  
D. Tyler McQuade ◽  
Peter H. Seeberger
Keyword(s):  
Singlet Oxygen ◽  
Continuous Flow ◽  
Secondary Amines ◽  
Primary And Secondary Amines

Catalytic alkyl group exchange reaction of primary and secondary amines

1983 ◽  
Vol 105 (15) ◽  
pp. 5002-5011 ◽  
Author(s):  
Shunichi Murahashi ◽  
Noriaki Yoshimura ◽  
Tatsuo Tsumiyama ◽  
Takeyuki Kojima
Keyword(s):  
Exchange Reaction ◽  
Alkyl Group ◽  
Secondary Amines ◽  
Primary And Secondary Amines
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