Analysis of estrogen receptors in human breast cancer by assays using monoclonal antibodies and by the dextran-coated charcoal method

1987 ◽  
Vol 17 (5) ◽  
pp. 369-376
Author(s):  
Noboru Fujino ◽  
Kiyoshi Sakamoto ◽  
Nobuyuki Shigaki ◽  
Jun-ichi Yamashita ◽  
Masaharu Kimura ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Monoclonal Antibodies ◽  
Estrogen Receptors ◽  
Human Breast Cancer ◽  
Human Breast ◽  
Dextran Coated Charcoal

Determination of Estrogen Receptors in Human Breast Cancer: Comparison between Enzyme Immunoassay and Dextran-Coated Charcoal Method

1986 ◽  
Vol 72 (5) ◽  
pp. 511-514 ◽  
Author(s):  
Cecilia Bozzetti ◽  
Nadia Naldi ◽  
Annamaria Guazzi ◽  
Rita Nizzoli ◽  
Magda Benecchi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Estrogen Receptors ◽  
Enzyme Immunoassay ◽  
Strong Correlation ◽  
Human Breast Cancer ◽  
Human Breast ◽  
Dextran Coated Charcoal ◽  
The Mean

Estrogen receptor determination was performed on 120 breast cancer cytosols, using the dextran-coated charcoal method (DCC) and an enzyme immunoassay (EIA) to compare the efficiency of the two techniques. A strong correlation was noted between ER concentrations determined by DCC and EIA (P < 0.001). The mean ER-EIA value was significantly higher than the mean ER-DCC value in premenopausal (P < 0.001) as well in postmenopausal (P < 0.001) patients.

Identification of structurally altered estrogen receptors in human breast cancer by site-directed monoclonal antibodies

Steroids ◽  
1995 ◽  
Vol 60 (7) ◽  
pp. 467-474 ◽  
Author(s):  
Abdulmaged M. Traish ◽  
Suad Al-Fadhli ◽  
Carolyn Klinge ◽  
Melissa Kounine ◽  
Timothy C. Quick
Keyword(s):  
Breast Cancer ◽  
Monoclonal Antibodies ◽  
Estrogen Receptors ◽  
Human Breast Cancer ◽  
Human Breast

Estrogen receptors in human breast cancer detected by the fluorescent estradiol histochemical and dextran coated charcoal techniques

1984 ◽  
Vol 14 (6) ◽  
pp. 459-464
Author(s):  
Masayuki Nishiki ◽  
Kuniki Amano ◽  
Motoi Yamane ◽  
Tsuneo Okumichi ◽  
Haruo Ezaki
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptors ◽  
Human Breast Cancer ◽  
Human Breast ◽  
Dextran Coated Charcoal

scholarly journals The use of monoclonal antibodies to estrogen receptors (ER) for immunoperoxidase detection of ER in paraffin sections of human breast cancer tissue.

1985 ◽  
Vol 33 (2) ◽  
pp. 87-92 ◽  
Author(s):  
H S Poulsen ◽  
L Ozzello ◽  
W J King ◽  
G L Greene
Keyword(s):  
Breast Cancer ◽  
Monoclonal Antibodies ◽  
Estrogen Receptors ◽  
Human Breast Cancer ◽  
Breast Cancer Tissue ◽  
Immunoperoxidase Staining ◽  
Cancer Tissue ◽  
Human Breast ◽  
Paraffin Sections ◽  
Human Breast Cancer Tissue

Two monoclonal antibodies against MCF-7 human estrogen receptors were used for immunoperoxidase staining of paraffin sections of human breast cancer tissue. The staining was predominantly located in the nucleus of epithelial cells. Variation in the staining intensity was observed among individual cells. A significant positive correlation between the number of positively stained cells and cytosol estrogen receptor content (fmol of bound estrogen/mg of protein) was observed. The potential and the limitations of the present techniques are discussed.

In Vivo Studies of Radiolabeled Monoclonal Antibodies Mc5 and KC4 in Human Breast Cancer

1989 ◽  
pp. 237-248
Author(s):  
Paul A. Bunn ◽  
David G. Dienhart ◽  
Raymond F. Schmelter ◽  
James L. Lear ◽  
Gary Miller ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Monoclonal Antibodies ◽  
Human Breast Cancer ◽  
In Vivo Studies ◽  
Human Breast
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