The current status of the treatment of ductal carcinoma in situ of japanese women, especially breast conserving operation in relation to the surgical margin and short term outcome

Breast Cancer ◽  
1998 ◽  
Vol 5 (1) ◽  
pp. 53-58 ◽  
Author(s):  
Tadashi Ikeda ◽  
Futoshi Akiyama ◽  
Masahiro Hiraoka ◽  
Hideo Inaji ◽  
Noriaki Ohuchi ◽  
...  
2016 ◽  
Vol 16 (4) ◽  
pp. 312-318 ◽  
Author(s):  
Talha Shaikh ◽  
Tianyu Li ◽  
Colin T. Murphy ◽  
Nicholas G. Zaorsky ◽  
Richard J. Bleicher ◽  
...  

Author(s):  
Abeer M. Shaaban ◽  
◽  
Bridget Hilton ◽  
Karen Clements ◽  
Elena Provenzano ◽  
...  

Abstract Background The Sloane audit compares screen-detected ductal carcinoma in situ (DCIS) pathology with subsequent management and outcomes. Methods This was a national, prospective cohort study of DCIS diagnosed during 2003–2012. Results Among 11,337 patients, 7204 (64%) had high-grade DCIS. Over time, the proportion of high-grade disease increased (from 60 to 65%), low-grade DCIS decreased (from 10 to 6%) and mean size increased (from 21.4 to 24.1 mm). Mastectomy was more common for high-grade (36%) than for low-grade DCIS (15%). Few (6%) patients treated with breast-conserving surgery (BCS) had a surgical margin <1 mm. Of the 9191 women diagnosed in England (median follow-up 9.4 years), 7% developed DCIS or invasive malignancy in the ipsilateral and 5% in the contralateral breast. The commonest ipsilateral event was invasive carcinoma (n = 413), median time 62 months, followed by DCIS (n = 225), at median 37 months. Radiotherapy (RT) was most protective against recurrence for high-grade DCIS (3.2% for high-grade DCIS with RT compared to 6.9% without, compared with 2.3 and 3.0%, respectively, for low/intermediate-grade DCIS). Ipsilateral DCIS events lessened after 5 years, while the risk of ipsilateral invasive cancer remained consistent to beyond 10 years. Conclusion DCIS pathology informs patient management and highlights the need for prolonged follow-up of screen-detected DCIS.


Cancer ◽  
2005 ◽  
Vol 103 (6) ◽  
pp. 1137-1146 ◽  
Author(s):  
Lawrence J. Solin ◽  
Alain Fourquet ◽  
Frank A. Vicini ◽  
Marie Taylor ◽  
Ivo A. Olivotto ◽  
...  

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