Reconstruction of thoracic wall defects after tumor resection using a polytetrafluoroethylene soft tissue (Gore-Tex) patch

This study aims to investigate the ability of ultrasound strain elastography as an adjunct to predict malignancy in soft tissue tumors suspect of sarcoma or metastasis in a tertiary reference center for sarcoma. A total of 137 patients were included prospectively. Patients were referred on the basis of clinical or radiological suspicion of malignant soft tissue tumor. All patients had previously undergone diagnostic imaging (MRI, CT or PET-CT). After recording strain elastography cine loops, ultrasound guided biopsy was performed. Three investigators, who were blinded to final diagnosis, reviewed all elastograms retrospectively. For each elastogram, a qualitative, visual 5-point score was decided in consensus and a strain ratio was calculated. Final pathology obtained from biopsy or tumor resection served as gold standard. Eighty-one tumors were benign, and 56 were malignant. t-tests showed a significant difference in mean visual score between benign and malignant tumors. There was no significant difference in mean strain ratio between the two groups. Strain elastography may be a valuable adjunct to conventional B-mode ultrasound, perhaps primarily in primary care, when considering whether to refer to a sarcoma center or to biopsy, although biopsies cannot reliably be ruled out based on the current data.

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Thoracic wall defects and reduction limb anomalies in two newborns—Effect of early amnionic rupture

Journal of Pediatric Surgery ◽

10.1016/0022-3468(90)90262-8 ◽

1990 ◽

Vol 25 (9) ◽

pp. 1002

Author(s):

Prem Puri

Keyword(s):

Thoracic Wall ◽

Limb Anomalies ◽

Thoracic Wall Defects

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Radiation-associated angiosarcoma after breast cancer: Improved survival by excision of all irradiated skin and soft tissue of the thoracic wall? A report of six patients

Acta Oncologica ◽

10.3109/0284186x.2014.983657 ◽

2014 ◽

Vol 54 (7) ◽

pp. 1078-1080 ◽

Cited By ~ 6

Author(s):

Emelie Styring ◽

Stina Klasson ◽

Anders Rydholm ◽

Fredrik Vult von Steyern

Keyword(s):

Breast Cancer ◽

Soft Tissue ◽

Thoracic Wall

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Sarcomas of the extremities and the pelvis: comparing local recurrence after incisional and after core-needle biopsy

World Journal of Surgical Oncology ◽

10.1186/s12957-021-02481-2 ◽

2022 ◽

Vol 20 (1) ◽

Author(s):

Alexander Klein ◽

Christof Birkenmaier ◽

Julian Fromm ◽

Thomas Knösel ◽

Dorit Di Gioia ◽

...

Keyword(s):

Soft Tissue ◽

Local Recurrence ◽

Core Needle Biopsy ◽

Needle Biopsy ◽

Tumor Resection ◽

Soft Tissue Sarcomas ◽

Wide Resection ◽

Incisional Biopsy ◽

Core Needle

Abstract Background The degree of contamination of healthy tissue with tumor cells during a biopsy in bone or soft tissue sarcomas is clearly dependant on the type of biopsy. Some studies have confirmed a clinically relevant contamination of the biopsy tract after incisional biopsies, as opposed to core-needle biopsies. The aim of our prospective study was to evaluate the risk of local recurrence depending on the biopsy type in extremity and pelvis sarcomas. Methods We included 162 patients with a minimum follow-up of 6 months after wide resection of extremity sarcomas. All diagnostic and therapeutic procedures were performed at a single, dedicated sarcoma center. The excision of the biopsy tract after an incisional biopsy was performed as a standard with all tumor resections. All patients received their follow-up after the conclusion of therapy at our center by means of regional MRI studies and, at a minimum, CT of the thorax to rule out pulmonary metastatic disease. The aim of the study was the evaluation of the influence of the biopsy type and of several other clinical factors on the rate of local recurrence and on the time of local recurrence-free survival. Results One hundred sixty-two patients with bone or soft tissue tumors of the extremities and the pelvis underwent either an incisional or a core-needle biopsy of their tumor, with 70 sarcomas (43.2%) being located in the bone. 84.6% of all biopsies were performed as core-needle biopsies. The median follow-up time was 55.6 months, and 22 patients (13.6%) developed a local recurrence after a median time of 22.4 months. There were no significant differences between incisional and core-needle biopsy regarding the risk of local recurrence in our subgroup analysis with differentiation by kind of tissue, grading of the sarcoma, and perioperative multimodal therapy. Conclusions In a large and homogenous cohort of extremity and pelvic sarcomas, we did not find significant differences between the groups of incisional and core-needle biopsy regarding the risk of local recurrence. The excision of the biopsy tract after incisional biopsy in the context of the definitive tumor resection seems to be the decisive factor for this result.

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