Usefulness of ultrasound-guided fine-needle aspiration cytology in the diagnosis of non-palpable small thyroid nodules: Our growing experience

2009 ◽  
Vol 32 (2) ◽  
pp. 156-159 ◽  
Author(s):  
A. Accurso ◽  
N. Rocco ◽  
A. Palumbo ◽  
C. Feleppa
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Thyroid Nodules ◽  
Needle Aspiration ◽  
Ultrasound Guided ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Usefulness of Ultrasound-Guided Fine-Needle Aspiration Cytology in the Diagnosis of Non-Palpable Small Thyroid Nodules

2005 ◽  
Vol 91 (4) ◽  
pp. 355-357 ◽  
Author(s):  
Antonello Accurso ◽  
Nicola Rocco ◽  
Alessio Palumbo ◽  
Francesco Leone
Keyword(s):  
Statistical Analysis ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Thyroid Nodules ◽  
Needle Aspiration ◽  
Ultrasound Guided ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Fine Needle Cytology ◽  
Needle Aspiration Cytology

Aims and background Diverse and contradictory approaches have been suggested for the management of non-palpable thyroid nodules. The aim of our study was to evaluate the indications and limits of ultrasound-guided fine-needle aspiration cytology (US-FNAC) in non-palpable infracentimetric thyroid nodules. Methods and study design From September 2003 to December 2004 we observed 325 patients with non-palpable thyroid nodules. We divided our series into three groups according to the diameter of the lesion in order to verify the effectiveness of US-FNAC for lesions of less than 1 cm. Results We assessed the cases with satisfactory and unsatisfactory results in the three groups into which the sample was divided (4 mm to 1 cm; 10.1 mm to 15 mm, and 15.1 mm to 25.5 mm). Our statistical analysis by means of the z-test showed there was no significant (5%) difference in the percentage distribution of the unsatisfactory results in the three groups. Conclusions Fine-needle cytology appears to be a useful diagnostic tool also for nodules of less than one cm because the percentage of unsatisfactory results is not related to the size of the nodule.

scholarly journals Malignancy rate in nondominant nodules in patients with multinodular goiter: Experience with 1,606 cases evaluated by ultrasound-guided fine needle aspiration cytology

CytoJournal ◽  
2011 ◽  
Vol 8 ◽  
pp. 19 ◽  
Author(s):  
Nadir Paksoy ◽  
Kadri Yazal ◽  
Selin Çorak
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Multinodular Goiter ◽  
Thyroid Nodules ◽  
Needle Aspiration ◽  
Ultrasound Guided ◽  
Aspiration Cytology ◽  
Significance Level ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Background: Conventional medical sources recommend the use of fine needle aspiration cytology (FNAC) for single thyroid nodules and the dominant nodule in multinodular goiter (MNG). The purpose of the present study was to analyze the utility of FNAC for multiple thyroid nodules in patients with MNG and to determine the rate of malignancy in teh nondominant nodules. Materials and Methods: Our private practice performed ultrasound-guided FNAC on 1,606 patients between February 2001 and February 1, 2010. In the MNG cases, samples were taken from the dominant nodule and from trhee suspicious / nonsuspicious nodules larger than 1 cm on ultrasound. Ninety-four cases were diagnosed as ‘suspiciously malignant’(SUS) or ‘malignant’ (POS) based on FNAC. Results: The rate of an SUS / POS diagnosis was 5.7% in the dominant nodules; 2.3% of the nondominant nodules had a SUS / POS diagnosis in FNAC (p = 0.0003). Follow-up revealed malignancy in 15 (35.7%) nondominant nodules and in 27 (64.2%) dominant nodules, with 42 MNG cases undergoing surgery. X test showed a ‘p-level of 0.0003’ between the percentages of SUS / POS diagnosis in dominanat and nondominanat nodules. It was less than the significance level of 0.05. Therefore, the result was regarded to be statistically significant. Conclusions: Nondominant nodules could harbor malignancy. The risk of malignancy in nondominant nodules in MNG should not be underestimated. We have shown that the dominant nodule in patients with MNG was in fact about 2.5 times more likely to be malignant than a nondominant nodule. The use of FNAC for nondominant nodules could enhance the likelihood of detecting malignancy in an MNG.

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