Unexpected partial H1-receptor agonism of imidazole-type histamine H3-receptor antagonists lacking a basic side chain

Inflammation Research ◽

10.1007/s00011-004-0351-8 ◽

2004 ◽

Vol 53 (S2) ◽

Author(s):

B. Sadek ◽

S. Elz ◽

H.H. Pertz ◽

H. Stark ◽

W. Schunack

Keyword(s):

H1 Receptor ◽

Receptor Antagonists ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

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Non-Imidazole Histamine H3 Ligands. Part VI. Synthesis and Preliminary Pharmacological Investigation of Thiazole-Type Histamine H3-Receptor Antagonists with Lacking a Nitrogen Nucleus in the Side Chain

Medicinal Chemistry ◽

10.2174/1573406412666160525121158 ◽

2016 ◽

Vol 13 (1) ◽

pp. 65-76 ◽

Author(s):

Roman Guryn ◽

Marek Staszewski ◽

Piotr Kopczacki ◽

Krzysztof Walczy.ski

Keyword(s):

Pharmacological Investigation ◽

Receptor Antagonists ◽

Histamine H3 Receptor ◽

Nitrogen Nucleus ◽

H3 Receptor ◽

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ChemInform Abstract: 4-Chlorobenzyl Sulfonamide and Sulfamide Derivatives of Histamine Homologues: The Design of Potent Histamine H3 Receptor Antagonists.

10.1002/chin.200008143 ◽

2010 ◽

Vol 31 (8) ◽

pp. no-no

Author(s):

Matthew J. Tozer ◽

Ildiko M. Buck ◽

Tracey Cooke ◽

S. Barret Kalindjian ◽

Iain M. McDonald ◽

...

Keyword(s):

Receptor Antagonists ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

Derivatives Of ◽

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ChemInform Abstract: Substituted N-Phenylcarbamates as Histamine H3 Receptor Antagonists with Improved in vivo Potency.

10.1002/chin.200024119 ◽

2010 ◽

Vol 31 (24) ◽

pp. no-no

Author(s):

S. Reidemeister ◽

H. Stark ◽

X. Ligneau ◽

C. R. Ganellin ◽

J.-C. Schwartz ◽

...

Keyword(s):

Receptor Antagonists ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

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Histamine H3 receptor antagonists ameliorate attention deficit/hyperactivity disorder-like behavioral changes caused by neonatal habenula lesion

Behavioural Pharmacology ◽

10.1097/fbp.0000000000000343 ◽

2018 ◽

Vol 29 (1) ◽

pp. 71-78 ◽

Author(s):

Yu-Jeong Kim ◽

Yukiori Goto ◽

Young-A Lee

Keyword(s):

Attention Deficit Hyperactivity Disorder ◽

Attention Deficit ◽

Behavioral Changes ◽

Receptor Antagonists ◽

Histamine H3 Receptor ◽

Hyperactivity Disorder ◽

H3 Receptor ◽

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Piperidine-Containing Histamine H3 Receptor Antagonists of the Carbamate Series: The Influence of the Additional Ether Functionality

10.1002/chin.200316136 ◽

2003 ◽

Vol 34 (16) ◽

Author(s):

D. Lazewska ◽

K. Kiec-Kononowicz ◽

H. H. Pertz ◽

S. Elz ◽

H. Stark ◽

...

Keyword(s):

Receptor Antagonists ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

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Keynote review: Histamine H3 receptor antagonists reach out for the clinic

Drug Discovery Today ◽

10.1016/s1359-6446(05)03625-1 ◽

2005 ◽

Vol 10 (23-24) ◽

pp. 1613-1627 ◽

Author(s):

Sylvain Celanire ◽

Maikel Wijtmans ◽

Patrice Talaga ◽

Rob Leurs ◽

Iwan J.P. de Esch

Keyword(s):

Receptor Antagonists ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

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Synthesis and evaluation of N-alkyl-S-[3-(piperidin-1-yl)propyl]isothioureas: High affinity and human/rat species-selective histamine H3 receptor antagonists

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2013.09.052 ◽

2013 ◽

Vol 23 (23) ◽

pp. 6415-6420 ◽

Author(s):

Shinya Harusawa ◽

Koichi Sawada ◽

Takuji Magata ◽

Hiroki Yoneyama ◽

Lisa Araki ◽

...

Keyword(s):

Receptor Antagonists ◽

Histamine H3 Receptor ◽

High Affinity ◽

H3 Receptor ◽

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Computational analysis of novel drugs designed for use as acetylcholinesterase inhibitors and histamine H3 receptor antagonists for Alzheimer's disease by docking, scoring and de novo evolution

Molecular Medicine Reports ◽

10.3892/mmr.2012.757 ◽

2012 ◽

Vol 5 (4) ◽

pp. 1043-1048 ◽

Author(s):

PO-YUAN CHEN ◽

CHING-TSAN TSAI ◽

CHE-YEN OU ◽

WEI-TSE HSU ◽

MIEN-DE JHUO ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Computational Analysis ◽

De Novo ◽

Acetylcholinesterase Inhibitors ◽

Receptor Antagonists ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

Novel Drugs ◽

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Non-imidazole heterocyclic histamine H3 receptor antagonists

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(03)00299-3 ◽

2003 ◽

Vol 13 (10) ◽

pp. 1767-1770 ◽

Author(s):

Wenying Chai ◽

J.Guy Breitenbucher ◽

Annette Kwok ◽

Xiaobing Li ◽

Victoria Wong ◽

...

Keyword(s):

Receptor Antagonists ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

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Medicinal chemistry of histamine H3 receptor antagonists

Pharmacochemistry Library - The Histamine H3 Receptor - A Target for New Drugs ◽

10.1016/s0165-7208(98)80031-7 ◽

1998 ◽

pp. 197-222

Author(s):

James G. Phillips ◽

Syed M. Ali

Keyword(s):

Medicinal Chemistry ◽

Receptor Antagonists ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

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