The Effect of Fibrinogen/Thrombin-Coated Collagen Patch (TachoSil®) Application in Pancreaticojejunostomy for Prevention of Pancreatic Fistula After Pancreaticoduodenectomy: A Randomized Clinical Trial

2019 ◽  
Vol 43 (12) ◽  
pp. 3128-3137 ◽  
Author(s):  
Jaewoo Kwon ◽  
Sang Hyun Shin ◽  
Sukyung Lee ◽  
Guisuk Park ◽  
Yejong Park ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Pancreatic Fistula ◽  
Randomized Clinical Trial ◽  
Coated Collagen

Randomized clinical trial of pancreaticogastrostomyversuspancreaticojejunostomy on the rate and severity of pancreatic fistula after pancreaticoduodenectomy

2013 ◽  
Vol 100 (12) ◽  
pp. 1597-1605 ◽  
Author(s):  
J. Figueras ◽  
L. Sabater ◽  
P. Planellas ◽  
E. Muñoz-Forner ◽  
S. Lopez-Ben ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Pancreatic Fistula ◽  
Randomized Clinical Trial

scholarly journals Randomized clinical trial of the effect of a fibrin sealant patch on pancreatic fistula formation after pancreatoduodenectomy

2018 ◽  
Vol 105 (7) ◽  
pp. 811-819 ◽  
Author(s):  
M. Schindl ◽  
R. Függer ◽  
P. Götzinger ◽  
F. Längle ◽  
M. Zitt ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Pancreatic Fistula ◽  
Randomized Clinical Trial ◽  
Fibrin Sealant ◽  
Fistula Formation

Central pancreatectomy combined with end-to-end anastomosis reconstruction versus conventional central pancreatectomy in robotic surgery: study protocol for a randomized clinical trial

2019 ◽  
Author(s):  
LIN ZHU ◽  
Gong Zhang ◽  
Jizhe Li ◽  
Haifeng Zhang ◽  
Fei Huang ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Robotic Surgery ◽  
Pancreatic Fistula ◽  
Randomized Clinical Trial ◽  
Exocrine Function ◽  
Complication Rates ◽  
Central Pancreatectomy ◽  
Pancreatic Neck ◽  
Malignant Lesions ◽  
End To End

Abstract [EXSCINDED] Abstract Abstract Background Central pancreatectomy (CP) is an ideal surgery option for benign and low malignant potential lesions in the neck and body of pancreas. CP maintains pancreatic endocrine and exocrine function better than distal pancreatectomy and pancreaticoduodenectomy, but it has a higher risk of pancreatic fistula1. Up to now, CP reported by Dagradi and Serio2 is the standard procedure. But our four-year experience suggests CP with end-to-end anastomosis could reduce pancreatic fistula and other complication rates. The aim of the trial is to investigate whether the CP combined with end-to-end anastomosis reconstruction approach can reduce the fistula rate of patients with pancreatic neck and body benign and low malignant lesions compared with the conventional approach. We hypothesize that CP combined with end-to-end anastomosis could be an alternative procedure of conventional CP.Methods/design The trial is a single center, randomized controlled trial with two parallel research group. The trial compares the possible advantages of CP combined with end-to-end anastomosis to conventional CP in robotic surgery. One hundred and seventy patients with pancreatic neck and body benign and low malignant lesions in Chinese People’s Liberation Army (PLA) General Hospital will be enrolled. The patients will be divided into two groups randomly. One group will choose CP with end-to-end anastomosis while the other group will use conventional CP. The primary endpoint will be postoperative pancreatic fistula (POPF) rate.Discussion There is no randomized clinical trial to estimate the advantages of CP with end-to-end anastomosis reconstruction. The CP with end-to-end anastomosis reconstruction in robotic surgery was first reported by Professor Liu in our department, and professional surgical techniques can reduce confounding factors and have high recruitment rate. For our research is a randomized clinical trial, we can provide high quality evidence on CP standard.

Efficacy of octreotide in the prevention of pancreatic fistula after elective pancreatic resections: A prospective, controlled, randomized clinical trial

Surgery ◽  
1995 ◽  
Vol 117 (1) ◽  
pp. 26-31 ◽  
Author(s):  
Marco Montorsi ◽  
Mauro Zago ◽  
Franco Mosca ◽  
Lorenzo Capussotti ◽  
Enzo Zotti ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Pancreatic Fistula ◽  
Randomized Clinical Trial ◽  
Pancreatic Resections

scholarly journals Effect of flowable thrombin-containing collagen-based hemostatic matrix for preventing pancreatic fistula after pancreatectomy: A randomized clinical trial

2021 ◽  
Vol 25 (1) ◽  
pp. S371-S371
Author(s):  
Yejong PARK ◽  
Jae Hyung KO ◽  
Dae Ryong KANG ◽  
Jun Hyeok LEE ◽  
Dae Wook HWANG ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Pancreatic Fistula ◽  
Randomized Clinical Trial
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