scholarly journals Editorial comment: Prognostic value of diffusion-weighted imaging in patients with newly diagnosed sporadic Creutzfeldt-Jakob disease

2022 ◽  
Author(s):  
Jinhee Jang
Keyword(s):  
Editorial Comment ◽  
Diffusion Weighted Imaging ◽  
Prognostic Value ◽  
Newly Diagnosed ◽  
Diffusion Weighted ◽  
Jakob Disease

Prognostic value of diffusion-weighted imaging in patients with newly diagnosed sporadic Creutzfeldt-Jakob disease

2021 ◽  
Author(s):  
Ho Young Park ◽  
Chong Hyun Suh ◽  
Woo Hyun Shim ◽  
Seon-Ok Kim ◽  
Woo Seok Kim ◽  
...  
Keyword(s):  
Diffusion Weighted Imaging ◽  
Prognostic Value ◽  
Newly Diagnosed ◽  
Diffusion Weighted ◽  
Jakob Disease

Comparison between whole-body MRI with diffusion-weighted imaging and PET/CT in staging newly diagnosed FDG-avid lymphomas.

2016 ◽  
Vol 85 (2) ◽  
pp. 313-318 ◽  
Author(s):  
Domenico Albano ◽  
Caterina Patti ◽  
Ludovico La Grutta ◽  
Francesco Agnello ◽  
Emanuele Grassedonio ◽  
...  
Keyword(s):  
Diffusion Weighted Imaging ◽  
Whole Body ◽  
Newly Diagnosed ◽  
Whole Body Mri ◽  
Diffusion Weighted ◽  
Pet Ct

scholarly journals Doença de Creutzfeldt-Jakob: Apresentação Atípica de uma Doença Muito Rara

2020 ◽  
Vol 33 (13) ◽  
Author(s):  
Renato Oliveira ◽  
Marta Dias ◽  
Inês Brás Marques
Keyword(s):  
Cerebrospinal Fluid ◽  
Magnetic Resonance ◽  
Diffusion Weighted Imaging ◽  
Negative Symptoms ◽  
Sudden Onset ◽  
Lower Limbs ◽  
Progressive Dementia ◽  
Radiological Features ◽  
Diffusion Weighted ◽  
Jakob Disease

Creutzfeldt-Jakob disease typically presents as rapidly progressive dementia. We describe the case of a 59-year-old male patient presenting with sudden onset of central facial palsy and dysarthria, followed by myoclonus of his left upper and lower limbs. Initial brain magnetic resonance showed hyperintensity of the right caudate and putamen on diffusion-weighted imaging and T2 sequences. Cerebrospinal fluid analysis showed increased protein count. The workup to investigate autoimmune, infectious and paraneoplastic causes was negative. Symptoms progressively worsened, with left hemiplegia, dysphagia, urinary incontinence, and, later, akinetic mutism. The follow-up brain magnetic resonance scan revealed hyperintensity of bilateral basal ganglia as well as cerebral cortical abnormalities on diffusion-weighted imaging. Electroencephalography showed periodic activity and tau protein levels in the cerebrospinal fluid were elevated. Genetic analysis showed mutation c-598G > A. The patient died four months later. We report a case of familial Creutzfeldt-Jakob disease with atypical clinical and radiological features, namely neurological focal signs with sudden onset, absence of significant cognitive impairment and unilateral radiological findings. With disease progression, characteristic clinical and radiological features led to the diagnosis.

scholarly journals The ABCD and ABCD2 Scores and the Risk of Stroke following a TIA: A Narrative Review

2011 ◽  
Vol 2011 ◽  
pp. 1-12 ◽  
Author(s):  
Archit Bhatt ◽  
Vishal Jani
Keyword(s):  
Atrial Fibrillation ◽  
Diffusion Weighted Imaging ◽  
Prognostic Value ◽  
Risk Scores ◽  
Large Artery ◽  
Imaging Data ◽  
Short Term ◽  
Vascular Events ◽  
Diffusion Weighted ◽  
Abcd2 Score

The California, ABCD, and ABCD2 risk scores (ABCD system) were developed to help stratify short-term stroke risk in patients with TIA (transient ischemic attack). Beyond this scope, the ABCD system has been extensively used to study other prognostic information such as DWI (diffusion-weighted imaging) abnormalities, large artery stenosis, atrial fibrillation and its diagnostic accuracy in TIA patients, which are independent predictors of subsequent stroke in TIA patients. Our comprehensive paper suggested that all scores have and equivalent prognostic value in predicting short-term risk of stroke; however, the ABCD2 score is being predominantly used at most centers. The majority of studies have shown that more than half of the strokes in the first 90 days, occur in the first 7 days. The majority of patients studied were predominantly classified to have a higher ABCD/ABCD2 > 3 scores and were particularly at a higher short-term risk of stroke or TIA and other vascular events. However, patients with low risk ABCD2 score < 4 may have high-risk prognostic indicators, such as diffusion weighted imaging (DWI) abnormalities, large artery atherosclerosis (LAA), and atrial fibrillation (AF). The prognostic value of these scores improved if used in conjunction with clinical information, vascular imaging data, and brain imaging data. Before more data become available, the diagnostic value of these scores, its applicability in triaging patients, and its use in evaluating long-term prognosis are rather secondary; thus, indicating that the primary significance of these scores is for short-term prognostic purposes.

Diffusion-weighted imaging negative M232R familial Creutzfeldt-Jakob disease

2019 ◽  
Vol 64 ◽  
pp. 47-49
Author(s):  
Yoon-Jung Kang ◽  
Kyung-Hye Kim ◽  
Sung-Hwan Jang ◽  
Gha-Hyun Lee ◽  
Yoon-Jung Lee ◽  
...  
Keyword(s):  
Diffusion Weighted Imaging ◽  
Diffusion Weighted ◽  
Jakob Disease
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