Morphology transition of polyion complex (PIC) micelles with carboxybetaine as a shell induced at different block ratios and their pH-responsivity

Author(s):  
Dongwook Kim ◽  
Hiro Honda ◽  
Hideki Matsuoka ◽  
Shin-ichi Yusa ◽  
Yoshiyuki Saruwatari
2021 ◽  
Vol 22 (2) ◽  
pp. 262-274
Author(s):  
Serge Mignani ◽  
Xiangyang Shi ◽  
Maria Zablocka ◽  
Jean-Pierre Majoral

2021 ◽  
Author(s):  
Wei Wen ◽  
Aihua Chen

Self-assembly of amphiphilic single chain Janus nanoparticles (SCJNPs) is a novel and promising approach to fabricate assemblies with diversified morphologies. However, the experimental research of the self-assembly behavior of SCJNPs...


Polymer ◽  
2021 ◽  
pp. 123589
Author(s):  
Jia-Wei Li ◽  
Miao Chen ◽  
Jie-Mei Zhou ◽  
Cai-Yuan Pan ◽  
Wen-Jian Zhang ◽  
...  

2020 ◽  
pp. 100918
Author(s):  
D. Paul Joseph ◽  
U. Devarajan ◽  
Jean Maria Fernandes ◽  
R. Ramarajan ◽  
M. Kovendhan ◽  
...  

Polymers ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 5
Author(s):  
Noriko Nakamura ◽  
Yuki Mochida ◽  
Kazuko Toh ◽  
Shigeto Fukushima ◽  
Horacio Cabral ◽  
...  

Self-assembled supramolecular structures based on polyion complex (PIC) formation between oppositely charged polymers are attracting much attention for developing drug delivery systems able to endure harsh in vivo environments. As controlling polymer complexation provides an opportunity for engineering the assemblies, an improved understanding of the PIC formation will allow constructing assemblies with enhanced structural and functional capabilities. Here, we focused on the influence of the mixing charge ratio between block aniomers and catiomers on the physicochemical characteristics and in vivo biological performance of the resulting PIC micelles (PIC/m). Our results showed that by changing the mixing charge ratio, the structural state of the core was altered despite the sizes of PIC/m remaining almost the same. These structural variations greatly affected the stability of the PIC/m in the bloodstream after intravenous injection and determined their biodistribution.


RSC Advances ◽  
2021 ◽  
Vol 11 (15) ◽  
pp. 8986-8992
Author(s):  
Qiumeng Chen ◽  
Yahui Li ◽  
Ming Liu ◽  
Xuan Wu ◽  
Jianliang Shen ◽  
...  

Helical nanowires were successfully synthesized through polymerization-induced self-assembly and subsequent aging. The achiral BCP nano-objects underwent a morphology transition from spheres to helical nanowires during aging.


2020 ◽  
Vol 53 (13) ◽  
pp. 5487-5496
Author(s):  
Yiping Wang ◽  
Yen Theng Cheng ◽  
Cheng Cao ◽  
James D. Oliver ◽  
Martina H. Stenzel ◽  
...  

2018 ◽  
Vol 270 ◽  
pp. 226-236 ◽  
Author(s):  
N.V. Nukolova ◽  
A.D. Aleksashkin ◽  
T.O. Abakumova ◽  
A.Y. Morozova ◽  
I.L. Gubskiy ◽  
...  

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