scholarly journals Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer’s disease, and dementia with Lewy bodies

2010 ◽  
Vol 119 (5) ◽  
pp. 579-589 ◽  
Author(s):  
Masafumi Ihara ◽  
Tuomo M. Polvikoski ◽  
Ros Hall ◽  
Janet Y. Slade ◽  
Robert H. Perry ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
White Matter ◽  
Vascular Dementia ◽  
Frontal Lobe ◽  
Dementia With Lewy Bodies ◽  
Lewy Bodies

Atrophy is associated with posterior cingulate white matter disruption in dementia with Lewy bodies and Alzheimer’s disease

NeuroImage ◽  
2007 ◽  
Vol 36 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Michael J. Firbank ◽  
Andrew M. Blamire ◽  
Mani S. Krishnan ◽  
Andrew Teodorczuk ◽  
Philip English ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
White Matter ◽  
Dementia With Lewy Bodies ◽  
Lewy Bodies ◽  
Posterior Cingulate

Quantifying fluctuation in dementia with Lewy bodies, Alzheimer's disease, and vascular dementia

Neurology ◽  
2000 ◽  
Vol 54 (8) ◽  
pp. 1616-1625 ◽  
Author(s):  
M. P. Walker ◽  
G. A. Ayre ◽  
J. L. Cummings ◽  
K. Wesnes ◽  
I. G. McKeith ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Vascular Dementia ◽  
Dementia With Lewy Bodies ◽  
Lewy Bodies

White matter changes in dementia with Lewy bodies and Alzheimer’s disease: A tractography-based study

2011 ◽  
Vol 45 (8) ◽  
pp. 1095-1100 ◽  
Author(s):  
Kuniaki Kiuchi ◽  
Masayuki Morikawa ◽  
Toshiaki Taoka ◽  
Soichiro Kitamura ◽  
Tomohisa Nagashima ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
White Matter ◽  
Dementia With Lewy Bodies ◽  
Lewy Bodies ◽  
White Matter Changes

Validity of current clinical criteria for Alzheimer's disease, vascular dementia and dementia with Lewy bodies

1999 ◽  
Vol 174 (1) ◽  
pp. 45-50 ◽  
Author(s):  
Clive Holmes ◽  
Nigel Cairns ◽  
Peter L. Lantos ◽  
Anthony Mann
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Vascular Dementia ◽  
Dementia With Lewy Bodies ◽  
Lewy Bodies ◽  
Community Based ◽  
Predictive Values ◽  
Clinical Criteria ◽  
Low Prevalence ◽  
Clinical Diagnostic Criteria

BackgroundFollowing the success of the NINCDS–ADRDA criteria for Alzheimer's disease, groups interested in vascular dementia and dementia with Lewy bodies have now adopted similar criteria.AimsTo assess whether the validity of these criteria are influenced by the prevalence of mixed pathologies or by the prevalence rate.MethodA community based postmortem study.ResultsMixed pathologies were common (33.8%). The high specificities obtained for the CDLB and NINDS–AIREN criteria (1.00 and 0.95, respectively) were associated with low sensitivities (0.22 and 0.43, respectively). Low prevalence and the presence of mixed pathologies had a deleterious effect on positive predictive values.ConclusionsCurrent clinical diagnostic criteria are good at detecting pathology per se but not at detecting pure pathology. A large proportion of subjects from the general population fulfilling probable CDLB, probable NINCDS–ADRDA or probable NINDS–AIREN will have mixed pathologies.

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