Morphological alteration of the pancreatic islet in ovariectomized rats fed a high-fat high-fructose diet

2022 ◽  
Author(s):  
Piyachat Chansela ◽  
Bubphachat Potip ◽  
Jittima Weerachayaphorn ◽  
Niwat Kangwanrangsan ◽  
Natsasi Chukijrungroat ◽  
...  
Keyword(s):  
Pancreatic Islet ◽  
Ovariectomized Rats ◽  
Morphological Alteration ◽  
High Fat ◽  
High Fructose Diet ◽  
High Fructose

Kombuchas from green and black teas reduce oxidative stress, liver steatosis and inflammation, and improve glucose metabolism in Wistar rats fed a high-fat high-fructose diet

2021 ◽  
Author(s):  
Rodrigo Cardoso ◽  
Luiza Dias Moreira ◽  
Mirian Costa ◽  
Renata Celi Lopes Toledo ◽  
Mariana Grancieri ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Lipid Metabolism ◽  
Glucose Metabolism ◽  
Wistar Rats ◽  
Liver Steatosis ◽  
Black Tea ◽  
High Fat ◽  
High Fructose Diet ◽  
High Fructose ◽  
Green And Black Tea

The aim of this study was to evaluate the effect of green and black tea kombuchas consumption on adiposity, lipid metabolism, liver steatosis, oxidative stress, and inflammation in Wistar rats...

Ezetimibe prevents hepatic steatosis induced by a high-fat but not a high-fructose diet

2013 ◽  
Vol 305 (2) ◽  
pp. E293-E304 ◽  
Author(s):  
Masateru Ushio ◽  
Yoshihiko Nishio ◽  
Osamu Sekine ◽  
Yoshio Nagai ◽  
Yasuhiro Maeno ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Liver Disease ◽  
Hepatic Steatosis ◽  
High Fat Diet ◽  
Fatty Acid Synthase ◽  
Binding Protein ◽  
High Fat ◽  
High Fructose Diet ◽  
High Fructose ◽  
Element Binding Protein

Nonalcoholic fatty liver disease is the most frequent liver disease. Ezetimibe, an inhibitor of intestinal cholesterol absorption, has been reported to ameliorate hepatic steatosis in human and animal models. To explore how ezetimibe reduces hepatic steatosis, we investigated the effects of ezetimibe on the expression of lipogenic enzymes and intestinal lipid metabolism in mice fed a high-fat or a high-fructose diet. CBA/JN mice were fed a high-fat diet or a high-fructose diet for 8 wk with or without ezetimibe. High-fat diet induced hepatic steatosis accompanied by hyperinsulinemia. Treatment with ezetimibe reduced hepatic steatosis, insulin levels, and glucose production from pyruvate in mice fed the high-fat diet, suggesting a reduction of insulin resistance in the liver. In the intestinal analysis, ezetimibe reduced the expression of fatty acid transfer protein-4 and apoB-48 in mice fed the high-fat diet. However, treatment with ezetimibe did not prevent hepatic steatosis, hyperinsulinemia, and intestinal apoB-48 expression in mice fed the high-fructose diet. Ezetimibe decreased liver X receptor-α binding to the sterol regulatory element-binding protein-1c promoter but not expression of carbohydrate response element-binding protein and fatty acid synthase in mice fed the high-fructose diet, suggesting that ezetimibe did not reduce hepatic lipogenesis induced by the high-fructose diet. Elevation of hepatic and intestinal lipogenesis in mice fed a high-fructose diet may partly explain the differences in the effect of ezetimibe.

The effect of high-fat–high-fructose diet on skeletal muscle mitochondrial energetics in adult rats

2014 ◽  
Vol 54 (2) ◽  
pp. 183-192 ◽  
Author(s):  
Raffaella Crescenzo ◽  
Francesca Bianco ◽  
Paola Coppola ◽  
Arianna Mazzoli ◽  
Luisa Cigliano ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
High Fat ◽  
Adult Rats ◽  
High Fructose Diet ◽  
High Fructose

Imperatorin attenuates cardiac remodelling and dysfunction in high-fat/high-fructose diet-fed rats by modulating oxidative stress, inflammation, and Nrf-2 expression

2022 ◽  
pp. 101728
Author(s):  
Patoomporn Prasartthong ◽  
Poungrat Pakdeechote ◽  
Putcharawipa Maneesai ◽  
Sariya Meephat ◽  
Siwayu Rattanakanokchai ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cardiac Remodelling ◽  
High Fat ◽  
High Fructose Diet ◽  
High Fructose
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