Voluntary exercise induces neurogenesis in the hypothalamus and ependymal lining of the third ventricle

2015 ◽  
Vol 221 (3) ◽  
pp. 1653-1666 ◽  
Author(s):  
Atsuko Niwa ◽  
Masahiro Nishibori ◽  
Shinichi Hamasaki ◽  
Takuro Kobori ◽  
Keyue Liu ◽  
...  
Keyword(s):  
Third Ventricle ◽  
Voluntary Exercise ◽  
The Third ◽  
Ependymal Lining

Scanning Electron Microscope of Supraependymal Neuronal Circuits in the Third Ventricle of Rhesus Monkey Brain

1990 ◽  
Vol 48 (3) ◽  
pp. 150-151
Author(s):  
A.K. Srivastava ◽  
V.K. Bajpai ◽  
D.R. Singh
Keyword(s):  
Third Ventricle ◽  
Lateral Wall ◽  
Structural Modifications ◽  
The Third ◽  
Critical Point Drying ◽  
Infundibular Recess ◽  
Supraependymal Cells ◽  
Perfusion Fixation ◽  
Ependymal Lining ◽  
Scanning Electron

The supraependymal neurons have been generally demonstrated lying over the nonciliated areas, specially CVOs, on the walls of the third cerebral ventricle of a variety of mammals. However, such neurons have till date been reported on the ciliated ependyma only inguinea pigs (Mitchell and Card, 1978). In the present study, third ventricles of nine adult monkeys of both the sexes were studied by routine scanning electron microscopy after perfusion fixation in 10 per cent neutral buffered formalin, dehydration with graded series of ethanol and amylacetate, critical-point-drying with liquid carbondioxide and sputter-coating with gold.Systematic scanning of the lateral wall of the third ventricle revealed that the ependymal surface could be divided into oligo-, and profusely ciliated zones. Pleomorphic supraependymal cells were noticed over the ciliated regions of the ventricularwall particularly between the thalamus and the mammillary region dorsal and caudal to the infundibular recess (Fig. 1). These neuron-like cells typically consisted of cell somas of variable configurations together with extensive networks of interconnected neuritic processes. At higher magnifications, the neuronal bodies depicted diverse structural modifications(Fig.2). Processes of variable diameters coursed over the ciliary carpet of the lateral wall of the third ventricle(Fig.3). At times, the processes exhibiting varicosities over the supramammillaryzone(Fig.4)coursed for variabledistances over the ependymal lining. The majority of such neuritic processes appeared to penetrate the underlying ventricular wall.

Gradients of histogenesis in the ependymal lining of the third ventricle in the rabbit

1986 ◽  
Vol 30 (2) ◽  
pp. 201-206 ◽  
Author(s):  
Victor Fernández ◽  
Rodrigo O. Kuljis
Keyword(s):  
Third Ventricle ◽  
The Third ◽  
Ependymal Lining

Endoscopic Surgery for Tumors in and around the Third Ventricle

2020 ◽  
Author(s):  
Kenichi Oyama ◽  
Toshio Hirohata ◽  
Keisuke Onoda ◽  
Shigeyuki Tahara ◽  
Akira Teramoto ◽  
...  
Keyword(s):  
Endoscopic Surgery ◽  
Third Ventricle ◽  
The Third

Clinical features and operative technique of transinfundibular craniopharyngioma

2020 ◽  
Vol 133 (1) ◽  
pp. 119-128 ◽  
Author(s):  
Bin Tang ◽  
ShenHao Xie ◽  
GuanLin Huang ◽  
ZhiGang Wang ◽  
Le Yang ◽  
...  
Keyword(s):  
Clinical Features ◽  
Operative Technique ◽  
Third Ventricle ◽  
Radical Resection ◽  
The Third ◽  
Expanded Endonasal Approach ◽  
Sequencing Studies ◽  
Characteristic Features ◽  
Mri Study ◽  
Adamantinomatous Craniopharyngioma

OBJECTIVETransinfundibular craniopharyngioma (TC) is one of the 4 subtypes of suprasellar craniopharyngioma. In this study, the authors analyzed the clinical features of and operative technique for TC.METHODSA total of 95 consecutive cases of suprasellar craniopharyngioma that had been resected via the endoscopic expanded endonasal approach were retrospectively reviewed. Patients were divided into 2 groups: 34 in the TC group and 61 in the nontransinfundibular craniopharyngioma (NC) group. Clinical and radiographic features, intraoperative findings, histopathological and genetic findings, and surgical outcomes were analyzed and compared between groups.RESULTSCompared with NC, TC was mostly seen in adult patients (97.1%); it was rare in children (2.9%). Clinical presentations tended toward headache, hydrocephalus, and diabetes insipidus. The relatively smaller volume, midline location (consistent with the stalk position), unidentifiable stalk, no shift of the third ventricle, and greater likelihood to involve the third ventricle and cause hydrocephalus were the characteristic features of TC in the preoperative MRI study. According to the degree of vertical extension of the tumor, the 34 TCs could be classified into 3 subtypes: type 1, entity was limited to stalk (n = 2, 5.9%); type 2, tumor extended up to the third ventricle (type 2a) or down to the subdiaphragmatic cavity (type 2b) (n = 23, 67.6%); and type 3, tumor extended in both directions (n = 9, 26.5%). For TC resection, the chiasm–pituitary corridor, lamina terminalis corridor, and pituitary corridor could be used separately or jointly. Most of the TCs originated from the infundibulum–tuber cinereum, grew within and along the long axis of the infundibulum, and the pituitary stalk was not usually preserved in TCs (20.6%), whereas the rate of preservation was higher (80.3%) in NCs. Bilateral hypothalamic injury was found in nearly all TCs if radical resection was performed, whereas the relationship between NCs and hypothalamus was either compression (32.8%) or unilateral invasion (67.2%). Meanwhile, the postoperative endocrine and neuropsychological function outcomes in patients with TC were worse than in patients with NC. The genetic analysis with whole-exome sequencing studies showed no differential mutations of CTNNB1 (β-catenin) and BRAF (V600E) between TC and NC subtypes, but there was a difference between adamantinomatous craniopharyngioma and papillary craniopharyngioma.CONCLUSIONSTC is a special subtype of suprasellar craniopharyngioma, which is remarkably different from NC. Identification of this type of tumor preoperatively is essential for the planning of appropriate surgical approach and degree of excision.

scholarly journals Development of a Prognostic Model to Predict Mortality after Traumatic Brain Injury in Intensive Care Setting in a Developing Country

2021 ◽  
Vol 12 (02) ◽  
pp. 368-375
Author(s):  
Mini Jayan ◽  
Dhaval Shukla ◽  
Bhagavatula Indira Devi ◽  
Dhananjaya I. Bhat ◽  
Subhas K. Konar
Keyword(s):  
Traumatic Brain Injury ◽  
Intensive Care ◽  
Brain Injury ◽  
Hospital Mortality ◽  
Prognostic Model ◽  
Third Ventricle ◽  
The Third ◽  
Scan Data ◽  
Gcs Score ◽  
Basal Cisterns

Abstract Objectives We aimed to develop a prognostic model for the prediction of in-hospital mortality in patients with traumatic brain injury (TBI) admitted to the neurosurgery intensive care unit (ICU) of our institute. Materials and Methods The clinical and computed tomography scan data of consecutive patients admitted after a diagnosis TBI in ICU were reviewed. Construction of the model was done by using all the variables of Corticosteroid Randomization after Significant Head Injury and International Mission on Prognosis and Analysis of Clinical Trials in TBI models. The endpoint was in-hospital mortality. Results A total of 243 patients with TBI were admitted to ICU during the study period. The in-hospital mortality was 15.3%. On multivariate analysis, the Glasgow coma scale (GCS) at admission, hypoxia, hypotension, and obliteration of the third ventricle/basal cisterns were significantly associated with mortality. Patients with hypoxia had eight times, with hypotensions 22 times, and with obliteration of the third ventricle/basal cisterns three times more chance of death. The TBI score was developed as a sum of individual points assigned as follows: GCS score 3 to 4 (+2 points), 5 to 12 (+1), hypoxia (+1), hypotension (+1), and obliteration third ventricle/basal cistern (+1). The mortality was 0% for a score of “0” and 85% for a score of “4.” Conclusion The outcome of patients treated in ICU was based on common admission variables. A simple clinical grading score allows risk stratification of patients with TBI admitted in ICU.

scholarly journals Survival of glioblastoma in relation to tumor location: a statistical tumor atlas of a population-based cohort

2021 ◽  
Author(s):  
Even Hovig Fyllingen ◽  
Lars Eirik Bø ◽  
Ingerid Reinertsen ◽  
Asgeir Store Jakola ◽  
Lisa Millgård Sagberg ◽  
...  
Keyword(s):  
Overall Survival ◽  
Prognostic Factor ◽  
Elderly Patients ◽  
Temporal Lobe ◽  
Third Ventricle ◽  
Tumor Location ◽  
Population Based ◽  
Independent Effect ◽  
Precentral Gyrus ◽  
The Third

Abstract Purpose Previous studies on the effect of tumor location on overall survival in glioblastoma have found conflicting results. Based on statistical maps, we sought to explore the effect of tumor location on overall survival in a population-based cohort of patients with glioblastoma and IDH wild-type astrocytoma WHO grade II–III with radiological necrosis. Methods Patients were divided into three groups based on overall survival: < 6 months, 6–24 months, and > 24 months. Statistical maps exploring differences in tumor location between these three groups were calculated from pre-treatment magnetic resonance imaging scans. Based on the results, multivariable Cox regression analyses were performed to explore the possible independent effect of centrally located tumors compared to known prognostic factors by use of distance from center of the third ventricle to contrast-enhancing tumor border in centimeters as a continuous variable. Results A total of 215 patients were included in the statistical maps. Central tumor location (corpus callosum, basal ganglia) was associated with overall survival < 6 months. There was also a reduced overall survival in patients with tumors in the left temporal lobe pole. Tumors in the dorsomedial right temporal lobe and the white matter region involving the left anterior paracentral gyrus/dorsal supplementary motor area/medial precentral gyrus were associated with overall survival > 24 months. Increased distance from center of the third ventricle to contrast-enhancing tumor border was a positive prognostic factor for survival in elderly patients, but less so in younger patients. Conclusions Central tumor location was associated with worse prognosis. Distance from center of the third ventricle to contrast-enhancing tumor border may be a pragmatic prognostic factor in elderly patients.

Neurosurgical anatomy of the floor of the third ventricle and related vascular structures

2021 ◽  
Author(s):  
João Fernandes-Silva ◽  
Susana M. Silva ◽  
Hélio Alves ◽  
José P. Andrade ◽  
Mavilde Arantes
Keyword(s):  
Third Ventricle ◽  
The Third ◽  
Vascular Structures
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