A direct comparison of tumor angiogenesis with 68Ga-labeled NGR and RGD peptides in HT-1080 tumor xenografts using microPET imaging

Amino Acids ◽  
2014 ◽  
Vol 46 (10) ◽  
pp. 2355-2364 ◽  
Author(s):  
Yahui Shao ◽  
Wansheng Liang ◽  
Fei Kang ◽  
Weidong Yang ◽  
Xiaowei Ma ◽  
...  
Keyword(s):  
Tumor Angiogenesis ◽  
Rgd Peptides ◽  
Micropet Imaging ◽  
Tumor Xenografts

scholarly journals Click Chemistry for18F-Labeling of RGD Peptides and microPET Imaging of Tumor Integrin αvβ3Expression

2007 ◽  
Vol 18 (6) ◽  
pp. 1987-1994 ◽  
Author(s):  
Zi-Bo Li ◽  
Zhanhong Wu ◽  
Kai Chen ◽  
Frederick T. Chin ◽  
Xiaoyuan Chen
Keyword(s):  
Click Chemistry ◽  
Rgd Peptides ◽  
Micropet Imaging

scholarly journals MicroPET Imaging of Integrin αvβ3 Expressing Tumors Using 89Zr-RGD Peptides

2010 ◽  
Vol 13 (6) ◽  
pp. 1224-1233 ◽  
Author(s):  
Orit Jacobson ◽  
Lei Zhu ◽  
Gang Niu ◽  
Ido D. Weiss ◽  
Lawrence P. Szajek ◽  
...  
Keyword(s):  
Integrin Αvβ3 ◽  
Rgd Peptides ◽  
Micropet Imaging

MicroPET imaging of tumor angiogenesis and monitoring on antiangiogenic therapy with an 18F labeled RGD-based probe in SKOV-3 xenograft-bearing mice

Tumor Biology ◽  
2014 ◽  
Vol 36 (5) ◽  
pp. 3285-3291 ◽  
Author(s):  
Guangjie Yang ◽  
Pei Nie ◽  
Yu Kong ◽  
Hukui Sun ◽  
Guihua Hou ◽  
...  
Keyword(s):  
Tumor Angiogenesis ◽  
Antiangiogenic Therapy ◽  
Micropet Imaging

scholarly journals Clinically Relevant Doses of Candesartan Inhibit Growth of Prostate Tumor Xenografts In Vivo through Modulation of Tumor Angiogenesis

2014 ◽  
Vol 350 (3) ◽  
pp. 635-645 ◽  
Author(s):  
Ahmed Alhusban ◽  
Ahmad Al-Azayzih ◽  
Anna Goc ◽  
Fei Gao ◽  
Susan C. Fagan ◽  
...  
Keyword(s):  
Tumor Angiogenesis ◽  
Prostate Tumor ◽  
Tumor Xenografts

scholarly journals αvβ3-Specific Gold Nanoparticles for Fluorescence Imaging of Tumor Angiogenesis

Nanomaterials ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 138
Author(s):  
Marc Pretze ◽  
Valeska von Kiedrowski ◽  
Roswitha Runge ◽  
Robert Freudenberg ◽  
René Hübner ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Optical Imaging ◽  
Tumor Angiogenesis ◽  
Near Infrared ◽  
Αvβ3 Integrin ◽  
A431 Cells ◽  
Rgd Peptides ◽  
Therapeutic Concepts

This paper reports on the development of tumor-specific gold nanoparticles (AuNPs) as theranostic tools intended for target accumulation and the detection of tumor angiogenesis via optical imaging (OI) before therapy is performed, being initiated via an external X-ray irradiation source. The AuNPs were decorated with a near-infrared dye, and RGD peptides as the tumor targeting vector for αvβ3-integrin, which is overexpressed in tissue with high tumor angiogenesis. The AuNPs were evaluated in an optical imaging setting in vitro and in vivo exhibiting favorable diagnostic properties with regards to tumor cell accumulation, biodistribution, and clearance. Furthermore, the therapeutic properties of the AuNPs were evaluated in vitro on pUC19 DNA and on A431 cells concerning acute and long-term toxicity, indicating that these AuNPs could be useful as radiosensitizers in therapeutic concepts in the future.

MicroPET imaging of brain tumor angiogenesis with 18F-labeled PEGylated RGD peptide

2004 ◽  
Vol 31 (8) ◽  
Author(s):  
Xiaoyuan Chen ◽  
Ryan Park ◽  
Yingping Hou ◽  
Vazgen Khankaldyyan ◽  
Ignacio Gonzales-Gomez ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Tumor Angiogenesis ◽  
Rgd Peptide ◽  
Micropet Imaging

Targeting adrenomedullin receptors with systemic delivery of neutralizing antibodies inhibits tumor angiogenesis and suppresses growth of human tumor xenografts in mice

2009 ◽  
Vol 23 (10) ◽  
pp. 3424-3435 ◽  
Author(s):  
Itidal Kaafarani ◽  
Samantha Fernandez-Sauze ◽  
Caroline Berenguer ◽  
Olivier Chinot ◽  
Christine Delfino ◽  
...  
Keyword(s):  
Tumor Angiogenesis ◽  
Neutralizing Antibodies ◽  
Human Tumor ◽  
Systemic Delivery ◽  
Human Tumor Xenografts ◽  
Tumor Xenografts
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