scholarly journals Antioxidant and anti-inflammatory functionality of ten Sri Lankan seaweed extracts obtained by carbohydrase assisted extraction

2018 ◽  
Vol 27 (6) ◽  
pp. 1761-1769 ◽  
Author(s):  
I. P. Shanura Fernando ◽  
K. K. Asanka Sanjeewa ◽  
Kalpa W. Samarakoon ◽  
Won Woo Lee ◽  
Hyun-Soo Kim ◽  
...  
Keyword(s):  
Sri Lankan ◽  
Seaweed Extracts ◽  
Assisted Extraction ◽  
Anti Inflammatory

scholarly journals Effects of Ultrasound-Assisted Extraction and Solvent on the Phenolic Profile, Bacterial Growth, and Anti-Inflammatory/Antioxidant Activities of Mediterranean Olive and Fig Leaves Extracts

Molecules ◽  
2020 ◽  
Vol 25 (7) ◽  
pp. 1718 ◽  
Author(s):  
Cristina Alcántara ◽  
Tihana Žugčić ◽  
Radhia Abdelkebir ◽  
Jose V. García-Pérez ◽  
Anet Režek Jambrak ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Bacterial Growth ◽  
Extraction Methods ◽  
Olive Leaves ◽  
Ultrasound Assisted Extraction ◽  
Phenolic Profile ◽  
Assisted Extraction ◽  
Ultrasound Assisted ◽  
Conventional Extraction ◽  
Anti Inflammatory

Mediterranean plants, such as fig and olive leaves, are well-known to exert beneficial effects in humans because of the presence of a wide range of bioactive compounds. However, scarce information regarding the impact of extraction methods, such as ultrasound and types of solvents, on their profile of antioxidant and anti-inflammatory compounds is provided. In addition, no information is available on the effects of extraction methods and solvents on the inhibition of pathogenic bacteria or promoting probiotic growth. In this scenario, this study was aimed to study the effects of ultrasound-assisted extraction (UAE) and solvent on the phenolic profile (Triple TOF-LC-MS/MS), antioxidant and anti-inflammatory compounds of olive and fig leaves. Results showed that UAE extracted more carotenoids compared to conventional extraction, while the conventional extraction impacted on higher flavonoids (olive leaves) and total phenolics (fig leaves). The antioxidant capacity of aqueous extract of fig leaves was three times higher than the extract obtained with ethanol for conventional extraction and four times higher for UAE. In general terms, hydroethanolic extracts presented the highest bacterial growth inhibition, and showed the highest anti-inflammatory activity. In conclusion, these side streams can be used as sources of bioactive compounds for further development of high-added-value products.

scholarly journals Ultrasonically-Assisted and Conventional Extraction from Erodium Glaucophyllum Roots Using Ethanol:Water Mixtures: Phenolic Characterization, Antioxidant, and Anti-Inflammatory Activities

Molecules ◽  
2020 ◽  
Vol 25 (7) ◽  
pp. 1759 ◽  
Author(s):  
Francisco J. Barba ◽  
Cristina Alcántara ◽  
Radhia Abdelkebir ◽  
Christine Bäuerl ◽  
Gaspar Pérez-Martínez ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Necrosis Factor Alpha ◽  
Assisted Extraction ◽  
Potent Inhibition ◽  
Tnf Α ◽  
Ultrasonic Assisted ◽  
Trolox Equivalent ◽  
Factor Alpha ◽  
Conventional Extraction ◽  
Anti Inflammatory

The paper presents experimental results concerning the ultrasonically-assisted extraction of bioactive compounds from Erodium glaucophyllum roots. A comparison with conventional methodology is presented, and thereby the phytochemical composition and the antioxidant and anti-inflammatory activities of extracts are evaluated. The phenolic profile of Erodium extracts was analyzed by TOF–LC–MS–MS. The identification of phenolic compounds revealed that the major component was (+)-gallocatechin in the aqueous extracts obtained for the different extraction methodologies. The highest quantity of phenolic compounds and antioxidant capacity was found in the hydroethanolic extract obtained by conventional extraction (29.22–25.50 mg GAE/g DM; 21.174 mM Trolox equivalent). The highest content of carotenoids, varying from 0.035 to 0.114 mg/g dry matter, was reached by ultrasonic-assisted extraction. Furthermore, Erodium extracts showed a potent inhibition of the inflammatory reaction by means of the inhibition of tumor necrosis factor-alpha (TNF-α). The extracts obtained when ultrasound extraction was combined with ethanol:water (50:50, v/v) presented the greatest inhibition (92%).

Chemical Characterization and Anti-inflammatory Activity of Polysaccharides from Zizyphus jujube cv. Muzao

2017 ◽  
Vol 13 (7) ◽  
Author(s):  
Xiaolong Ji ◽  
Qiang Peng ◽  
Huanyu Li ◽  
Fang Liu ◽  
Min Wang
Keyword(s):  
Chemical Characterization ◽  
Type I ◽  
Dependent Manner ◽  
Necrosis Factor Alpha ◽  
Assisted Extraction ◽  
Ultrasonic Assisted ◽  
Potential Applications ◽  
Anti Inflammatory ◽  
Zizyphus Jujube

AbstractPolysaccharides fromZizyphus jujube cv. Muzao(ZMP) were extracted by ultrasonic-assisted extraction with acidic buffer. The chemical composition and antioxidant and anti-inflammatory activities of ZMP were evaluated. The results revealed that ZMP had a molecular weight of 89.90 kDa and consisted of arabinose, galactose, glucose, rhamnose, and mannose, with molar percentages of 4.52 %, 2.64 %, 1.04 %, 0.49 %, and 0.41 %, respectively. Based on Fourier-transform infrared spectroscopy, ZMP belonged to the type I rhamnogalacturonans family. In vitro antioxidants assays revealed that ZMP had remarkable antioxidant activity in a dose-dependent manner. Proinflammatory cytokines, such as interleukin-6 and tumor necrosis factor alpha, were suppressed by ZMP in lipopolysaccharide-treated RAW264.7 cells. Overall, the results revealed that ZMP has potential applications as a natural anti-inflammatory agent.

Enzyme-assisted extraction of Ecklonia cava fermented with Lactobacillus brevis and isolation of an anti-inflammatory polysaccharide

ALGAE ◽  
2011 ◽  
Vol 26 (4) ◽  
pp. 343-350 ◽  
Author(s):  
Won-Woo Lee ◽  
Ginnae Ahn ◽  
W.A.J.P. Wijesinghe ◽  
Xiudong Yang ◽  
Chang-Ik Ko ◽  
...  
Keyword(s):  
Lactobacillus Brevis ◽  
Ecklonia Cava ◽  
Assisted Extraction ◽  
Anti Inflammatory ◽  
Enzyme Assisted Extraction

scholarly journals Penentuan Kadar Alkaloid Total pada Ekstrak Bunga Pepaya (Carica papaya L) dengan Metode Microwave Assisted Extraction

2018 ◽  
Vol 1 (2) ◽  
pp. 66
Author(s):  
Iman Mukhaimin ◽  
Anne Nur Latifahnya ◽  
Ernawati Puspitasari
Keyword(s):  
Carica Papaya ◽  
Microwave Assisted Extraction ◽  
Microwave Assisted ◽  
Assisted Extraction ◽  
Anti Inflammatory

<p>Bunga pepaya (<em>Carica papaya</em><em> L</em>) mengandung senyawa bioaktif alkaloid seperti <em>carpaine</em>, <em>pseudocarpaine</em> dan <em>dehydrocarpaine</em>. Alkaloid tersebut dipercaya bermanfaat untuk sebagai obat <em>antidengue, anti­cancer, antimicrobial, antiparasitic, anti-inflammatory, antioxidant, antidiabetic activities</em>. Pada penelitian ini, bunga pepaya diekstrak menggunakan metode ekstraksi padat-cair menggunakan metode <em>Microwave Assisted Extraction</em> (MAE) dan ekstraksi cair-cair. Sebelum proses ekstraksi, bunga pepaya dikeringkan dan dikecilkan hingga memiliki ukuran partikel sebesar 0,125 mm. Bunga pepaya yang telah kering diekstraksi menggunakan metanol 80% (<sup>v/</sup><sub>v</sub> untuk menentukan pengaruh waktu ekstraksi (1-5 menit), daya <em>microwave</em> (40, 120, 200, 280 Watt), dan rasio sampel terhadap pelarut ( 1:10 ; 1:15 ; 1:20 <sup>b</sup>/<sub>v</sub><sup>) </sup>terhadap kadar alkaloid total. Hasil ekstrak menunjukkan hasil positif adanya alkaloid setelah diuji dengan pereaksi Mayer dengan terbentuknya endapan berwarna putih kekuningan. Adapun kadar <em> </em>alkaloid total  terbesar adalah 0,02981 mg/g sampel dengan kondisi operasi ekstraksi waktu ekstraksi 3 menit, rasio sampel terhadap pelarut 1:10 (m/v) serta daya <em>microwave </em>40 Watt.</p>

scholarly journals Antioxidant, Anti-Inflammatory and Antibacterial Activities of the Seeds of A Sri Lankan Variety of Carica Papaya

2019 ◽  
Vol 12 (2) ◽  
pp. 539-547
Author(s):  
Akshani Anjula Wijesooriya ◽  
Srianthie A. Deraniyagala ◽  
Chamari M. Hettiarachchi
Keyword(s):  
Ascorbic Acid ◽  
Phenolic Content ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Total Phenolic ◽  
Sri Lankan ◽  
Scavenging Activity ◽  
Flavonoid Content ◽  
Anti Inflammatory

Plant based remedies are of much importance in healthcare due to low side effects. The effective constituents contained in seeds of a papaya have not been utilized efficiently in the production of medicines. The purpose of this study was driven towards determining the total phenolic content, total flavonoid content, antioxidant capacity, anti-inflammatory activity and antibacterial properties of the aqueous seeds extract of a Sri Lankan variety (Red Lady) of papaya (AESP). The AESP prepared according to the method of “Kasaya” in Ayurvedic medicine was used for the investigations according to standard procedures. Total phenolic content and the total flavonoid content of the AESP were 13.5±2.2 mg (pyrogallol equivalence)/g and 315.9±104.6 mg (quercetin equivalence)/g respectively. The 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity of AESP ranged from 12.4% to 81.2% for concentrations of 1.0-20.0 mg/ml; ascorbic acid gave 31.7% - 91.9% activity. The AESP displayed strong reducing power compared to ascorbic acid in the reducing power assay. The hydroxyl radical scavenging activity of the AESP ranged from 6.6% to 69.1% for concentrations ranging from 20.0-95.0 mg/ml; ascorbic acid activity was 37.7%-74.9%. The nitric oxide radical scavenging activity of AESP was 23.9%-62.7% for concentrations of 2.0-20.0 µg/ml; ascorbic acid gave 26.8%-63.5% activity. AESP concentrations ranging from 75.0-150.0 µg/ml exhibited human red blood cell (HRBC) membrane stabilization protection of 15.5%-22.7% compared to 50.8%-58.4% for aspirin. The AESP showed antibacterial activity against Bacillus subtilis and Staphylococcus aureus bacterial species. AESP possess promising antioxidant, anti-inflammatory and antibacterial activity. The aqueous decoction of the discarded seeds of papaya would facilitate remedies for many diseases in which radicals are implicated as well as assist against certain bacterial infections and also has an anti-inflammatory potential.

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