scholarly journals Evaluation of postoperative quality of life by PGSAS-45 following local gastrectomy based on the sentinel lymph node concept in early gastric cancer

2020 ◽  
Vol 23 (4) ◽  
pp. 746-753 ◽  
Author(s):  
Keishi Okubo ◽  
Takaaki Arigami ◽  
Daisuke Matsushita ◽  
Ken Sasaki ◽  
Takashi Kijima ◽  
...  
1995 ◽  
Vol 28 (12) ◽  
pp. 2242-2247
Author(s):  
Tsuguo Fujioka ◽  
Kiyoshi Sawai ◽  
Miyakatsu Ohara ◽  
Hiroshi Minato ◽  
Yuichi Yada ◽  
...  

Endoscopy ◽  
2020 ◽  
Vol 52 (06) ◽  
pp. 435-443 ◽  
Author(s):  
Su Mi Kim ◽  
Byung-Hoon Min ◽  
Joong Hyun Ahn ◽  
Sin-Ho Jung ◽  
Ji Yeong An ◽  
...  

Abstract Background The indications for endoscopic dissection have been expanded to improve the quality of life of patients with early gastric cancer (EGC). This study aimed to develop a nomogram to predict the status of lymph node metastasis with the aim of avoiding unnecessary gastrectomies. Methods We reviewed the clinicopathological data of 10 579 patients who underwent curative resection for EGC. The nomogram was developed by multivariate analysis and was evaluated by external validation. Overall, disease-free and recurrence-free survival were compared between the gastrectomy group of 6641 patients and the endoscopic dissection group of 999 patients to show the efficacy of the nomogram. Results Multivariate analyses revealed that age, tumor size, lymphatic invasion, depth of invasion, and histologic differentiation were all significant prognostic factors for lymph node metastasis. The nomogram had good discriminatory performance, with a concordance index of 0.846. This was supported by the external validation point of 0.813. For patients with low risk of lymph node metastasis on the nomogram (≤ 3 % of the provisional value in this study), the endoscopic dissection and gastrectomy groups had comparable rates of overall (P = 0.32), disease-free (P = 0.47), and recurrence-free (P = 0.09) survival. Conclusions We developed and validated a nomogram that predicts the risk of lymph node metastasis in EGC based on a large database. This precision nomogram is useful to avoid unnecessary gastrectomy after endoscopic dissection, which may ultimately improve the quality of life of patients with EGC.


Author(s):  
Hideo SUDO ◽  
Yu TAKAGI ◽  
Shigeru TSURUI ◽  
Soh KATAYANAGI ◽  
Kazushige ITO ◽  
...  

2019 ◽  
Vol 86 (11-12) ◽  
pp. 51-55
Author(s):  
V. V. Grubnik ◽  
Yu. V. Grubnik ◽  
R. P. Nikitenko

Objective. To study a possibility of performance of nonstandard organ-preserving operations in patients, suffering early gastric cancer, using application of the sentinel lymph nodes visualization procedures and the lymph node dissection procedure. Materials and methods. There were performed operative interventions in 35 patients, suffering early gastric cancer (Stages T1 and T2). For identification of sentinel lymph nodes a procedure of luminescence, using green indocyan, was applied. Results.  In all the patients early gastric cancer was diagnosed (T1,T2). Possibility for performance of organ-preserving operations in early gastric cancer was shown. Miniinvasive interventions in a patient with severe concurrent diseases have appeared sufficiently effective and radical. The patients’ quality of life after laparoscopic pylorus-preserving and organ-preserving operations was significantly better, than quality of life in patients, to whom gastric resection with extended D2 lymph node dissection was done. Conclusion. There was established, that intraoperative lymphography constitutes he informative method, which helps to estimate the disease Stage in gastric cancer and to apply the adequate scheme of combined and complex treatment. More sensitive is a procedure of luminescence, using green indocyan. Determination of the affection degree of «sentinel lymph nodes» in gastric cancer may serve as an argument for change of the selection tactics while changing the tactics for the operative intervention volume choice.


2022 ◽  
Vol 164 (1) ◽  
pp. 25-26
Author(s):  
Megan Lander ◽  
Kate Dugan ◽  
Jaden Kohn ◽  
Stephanie Wethington ◽  
Edward Tanner ◽  
...  

1998 ◽  
Vol 31 (4) ◽  
pp. 1015-1019
Author(s):  
Tetsuro Kubota ◽  
Yoichiro Ishikawa ◽  
Soichiro Isshiki ◽  
Takeyoshi Yokoyama ◽  
Koji Fujita ◽  
...  

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