Comparison of in vitro fertilization/intracytoplasmic sperm injection on live birth rates in couples with non-male factor infertility and advanced maternal age: overlooked details

2021 ◽  
Author(s):  
Enver Kerem Dirican ◽  
Safak Olgan
Keyword(s):  
In Vitro Fertilization ◽  
Live Birth ◽  
Intracytoplasmic Sperm Injection ◽  
Maternal Age ◽  
Advanced Maternal Age ◽  
Male Factor Infertility ◽  
Male Factor ◽  
Vitro Fertilization ◽  
Live Birth Rates

scholarly journals Overcoming male factor infertility with intracytoplasmic sperm injection

2017 ◽  
Vol 63 (8) ◽  
pp. 697-703 ◽  
Author(s):  
Edson Borges Jr. ◽  
Bianca Ferrarini Zanetti ◽  
Daniela Paes de Almeida Ferreira Braga ◽  
Amanda Souza Setti ◽  
Rita de Cássia Sávio Figueira ◽  
...  
Keyword(s):  
Intracytoplasmic Sperm Injection ◽  
Maternal Age ◽  
Age Groups ◽  
Control Group ◽  
Male Factor Infertility ◽  
Male Factor ◽  
Vitro Fertilization ◽  
Tubal Factor ◽  
Icsi Outcomes

Summary Objective: To evaluate the effect of male factor infertility on intracytoplasmic sperm injection (ICSI) outcomes compared with a control group presenting isolated tubal factor. Method: This retrospective study included 743 couples undergoing ICSI as a result of isolated male factor and a control group consisting of 179 couples undergoing ICSI as a result of isolated tubal factor, performed in a private university- -affiliated in vitro fertilization center, between January/2010 and December/2016. Patients were divided into two groups according to maternal age: women ≤35 years old and >35 years old. The effects of infertility causes on laboratorial and clinical ICSI outcomes were evaluated using Student's t-test and (2 test. Results: No differences in controlled ovarian stimulation outcomes were observed between male factor cycles and tubal factor cycles in the two age groups. Implantation (male factor 35.5% vs. tubal factor 32.0%, p=0.340), pregnancy (male factor 46.9% vs. tubal factor 40.9%, p=0.184) and miscarriage (male factor 10.3% vs. tubal factor 10.6%, p=0.572) rates were similar between the infertility groups, irrespective of female age. Considering maternal age, the cancelation rate was higher in older women (>35 years old) undergoing ICSI as a result of male factor infertility (17.4% vs. 8.9%, p=0.013). Conclusion: Our results showed that there is no difference in the outcomes of pregnancy between couples with male or tubal factor infertility, which indicates that ICSI surpasses the worse specific outcomes associated with male factor.

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