Curcumin-supplemented diets improve antioxidant enzymes and alter acetylcholinesterase genes expression level in Drosophila melanogaster model

2017 ◽  
Vol 33 (2) ◽  
pp. 369-375 ◽  
Author(s):  
Ayodele Jacob Akinyemi ◽  
Ganiyu Oboh ◽  
Opeyemi Ogunsuyi ◽  
Amos Olalekan Abolaji ◽  
Adetutu Udofia
Keyword(s):  
Drosophila Melanogaster ◽  
Antioxidant Enzymes ◽  
Expression Level ◽  
Genes Expression

Green Cardamom Plus Low Calorie Diet Can Decrease Inflammatory Genes Expression Among Obese Women With Poly Cystic Ovarian Syndrome, A Double Blind Randomized Clinical Trial

2021 ◽  
Author(s):  
Sahar Cheshmeh ◽  
Maysa Ghayyem ◽  
Firoozeh Khamooshi ◽  
Neda Heydarzadeh ◽  
Niloofar Hojati ◽  
...  
Keyword(s):  
Expression Level ◽  
Low Grade ◽  
Obese Women ◽  
Double Blind ◽  
Low Calorie ◽  
Low Calorie Diet ◽  
Genes Expression ◽  
Tnf Α ◽  
Calorie Diet ◽  
Green Cardamom

Abstract PurposePolycystic ovary syndrome (PCOS) is a common cause of endocrine disorder and infertility among womenin which is related with low grade inflammation. Therefore, this current randomized, double-blind, placebo-controlledclinical trial assessed the effects of green cardamom supplementation on inflammatory markers and gene expressionamong obese women with PCOS.MethodsWe included 194 obese PCOS women that gave all of them low calorie diet. These subjects were randomlydivided in two studied groups including intervention with 3 g/day green cardamom (n=99) and placebo groups (n=95).Anthropometric indices, androgen hormones, and inflammatory factors (tumor necrosis factor-a (TNF-α), Interleukin6 (IL-6), and C- reactive protein (CRP)) were assessed before and after four months intervention. Their TNF-α, IL-6,and CRP genes expression level were measured using reverse transcription-polymerase chain reaction (RT-PCR)method.ResultsAnthropometric indices were improved in both two studied groups (P<0.001). Among androgen hormonesluteinizing hormone, androstenedione, and dehydroepiandrosterone were significantly decreased (P<0.001), as wellas, follicle-stimulating hormone was significantly increased (P<0.001) in the green cardamom group. Our findingsshowed that TNF-α, IL-6, and CRP serum were significantly decreased after the intervention with green cardamomplus low calorie diet (P<0.001). In addition, the expression level of TNF-α and CRP genes were significantly decreasedin intervention groups (P<0.001).ConclusionsThis present study support the beneficial anti-inflammatory effect of green cardamom on theinflammatory status in the PCOS women.Level of evidenceLevel I, randomized clinical trialTrial registrationThis trial was registered with the Iranian Clinical Trials Registry (registration number:IRCT20200608047697N1). 1 August, 2020; https://www.irct.ir/trial/48748

scholarly journals Effect of Low Doses (5-40 cGy) of Gamma-irradiation on Lifespan and Stress-related Genes Expression Profile in Drosophila melanogaster

PLoS ONE ◽  
2015 ◽  
Vol 10 (8) ◽  
pp. e0133840 ◽  
Author(s):  
Svetlana Zhikrevetskaya ◽  
Darya Peregudova ◽  
Anton Danilov ◽  
Ekaterina Plyusnina ◽  
George Krasnov ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Gamma Irradiation ◽  
Expression Profile ◽  
Low Doses ◽  
Genes Expression ◽  
Stress Related Genes

scholarly journals Expression Level of sarah, a Homolog of DSCR1, Is Critical for Ovulation and Female Courtship Behavior in Drosophila melanogaster

Genetics ◽  
2004 ◽  
Vol 168 (4) ◽  
pp. 2077-2087 ◽  
Author(s):  
Aki Ejima ◽  
Manabu Tsuda ◽  
Satomi Takeo ◽  
Kunimasa Ishii ◽  
Takashi Matsuo ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Courtship Behavior ◽  
Expression Level

scholarly journals The influence of malachite green on the level of transcriptional expression of the laccase and DyP-peroxidase genes of the Azospirillum brasilense

2020 ◽  
Author(s):  
M. A. Kupryashina ◽  
T. E. Pylaev ◽  
V. E. Nikitina
Keyword(s):  
Malachite Green ◽  
Azospirillum Brasilense ◽  
Expression Level ◽  
Synthetic Dyes ◽  
Transcriptional Expression ◽  
Bacterial Enzymes ◽  
Genes Expression

Malachite green (MG), a widely-used and recalcitrant dye, has been confirmed to be carcinogenic and mutagenic against many organisms. Herein, we were aimed at the investigation of the hypothetic role of ligninolytic bacterial enzymes similar to fungal ones in the degradation of synthetic dyes. A multiple increase in the laccases and DyP-peroxidases genes expression level was recorded by RT-qPCR for bacteria of the genus Azospirillum in the presence of MG.

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