Curcumin-supplemented diets improve antioxidant enzymes and alter acetylcholinesterase genes expression level in Drosophila melanogaster model

2017 ◽  
Vol 33 (2) ◽  
pp. 369-375 ◽  
Author(s):  
Ayodele Jacob Akinyemi ◽  
Ganiyu Oboh ◽  
Opeyemi Ogunsuyi ◽  
Amos Olalekan Abolaji ◽  
Adetutu Udofia
2021 ◽  
Author(s):  
Sahar Cheshmeh ◽  
Maysa Ghayyem ◽  
Firoozeh Khamooshi ◽  
Neda Heydarzadeh ◽  
Niloofar Hojati ◽  
...  

Abstract PurposePolycystic ovary syndrome (PCOS) is a common cause of endocrine disorder and infertility among womenin which is related with low grade inflammation. Therefore, this current randomized, double-blind, placebo-controlledclinical trial assessed the effects of green cardamom supplementation on inflammatory markers and gene expressionamong obese women with PCOS.MethodsWe included 194 obese PCOS women that gave all of them low calorie diet. These subjects were randomlydivided in two studied groups including intervention with 3 g/day green cardamom (n=99) and placebo groups (n=95).Anthropometric indices, androgen hormones, and inflammatory factors (tumor necrosis factor-a (TNF-α), Interleukin6 (IL-6), and C- reactive protein (CRP)) were assessed before and after four months intervention. Their TNF-α, IL-6,and CRP genes expression level were measured using reverse transcription-polymerase chain reaction (RT-PCR)method.ResultsAnthropometric indices were improved in both two studied groups (P<0.001). Among androgen hormonesluteinizing hormone, androstenedione, and dehydroepiandrosterone were significantly decreased (P<0.001), as wellas, follicle-stimulating hormone was significantly increased (P<0.001) in the green cardamom group. Our findingsshowed that TNF-α, IL-6, and CRP serum were significantly decreased after the intervention with green cardamomplus low calorie diet (P<0.001). In addition, the expression level of TNF-α and CRP genes were significantly decreasedin intervention groups (P<0.001).ConclusionsThis present study support the beneficial anti-inflammatory effect of green cardamom on theinflammatory status in the PCOS women.Level of evidenceLevel I, randomized clinical trialTrial registrationThis trial was registered with the Iranian Clinical Trials Registry (registration number:IRCT20200608047697N1). 1 August, 2020; https://www.irct.ir/trial/48748


2020 ◽  
Vol 99 ◽  
pp. 379-385 ◽  
Author(s):  
Seyed Hossein Hoseinifar ◽  
Meysam Shakouri ◽  
Hien Van Doan ◽  
Shafigh Shafiei ◽  
Morteza Yousefi ◽  
...  

PLoS ONE ◽  
2015 ◽  
Vol 10 (8) ◽  
pp. e0133840 ◽  
Author(s):  
Svetlana Zhikrevetskaya ◽  
Darya Peregudova ◽  
Anton Danilov ◽  
Ekaterina Plyusnina ◽  
George Krasnov ◽  
...  

Genetics ◽  
2004 ◽  
Vol 168 (4) ◽  
pp. 2077-2087 ◽  
Author(s):  
Aki Ejima ◽  
Manabu Tsuda ◽  
Satomi Takeo ◽  
Kunimasa Ishii ◽  
Takashi Matsuo ◽  
...  

Author(s):  
M. A. Kupryashina ◽  
T. E. Pylaev ◽  
V. E. Nikitina

Malachite green (MG), a widely-used and recalcitrant dye, has been confirmed to be carcinogenic and mutagenic against many organisms. Herein, we were aimed at the investigation of the hypothetic role of ligninolytic bacterial enzymes similar to fungal ones in the degradation of synthetic dyes. A multiple increase in the laccases and DyP-peroxidases genes expression level was recorded by RT-qPCR for bacteria of the genus Azospirillum in the presence of MG.


2019 ◽  
Vol 26 (12) ◽  
pp. 12446-12458 ◽  
Author(s):  
Amna Shoaib ◽  
Zahra Nisar ◽  
Nafisa ◽  
Arshad Javaid ◽  
Saba Khurshid ◽  
...  

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