Cortico-hippocampal memory enhancing activity of hesperetin on scopolamine-induced amnesia in mice: role of antioxidant defense system, cholinergic neurotransmission and expression of BDNF

2019 ◽  
Vol 34 (4) ◽  
pp. 979-989 ◽  
Author(s):  
Ismail O. Ishola ◽  
Abosi A. Jacinta ◽  
Olufunmilayo O. Adeyemi
2015 ◽  
Vol 30 (6) ◽  
pp. 1465-1465 ◽  
Author(s):  
Juliana Lenzi ◽  
Andre Felipe Rodrigues ◽  
Adriana de Sousa Rós ◽  
Amanda Blanski de Castro ◽  
Daniela Delwing de Lima ◽  
...  

2004 ◽  
Vol 26 (3) ◽  
pp. 211-218 ◽  
Author(s):  
Işıl Öncel ◽  
Ender Yurdakulol ◽  
Yüksel Keleş ◽  
Latif Kurt ◽  
Atilla Yıldız

2004 ◽  
Vol 422 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Marcos S Dreon ◽  
Guillermo Schinella ◽  
Horacio Heras ◽  
Ricardo J Pollero

2000 ◽  
Vol 78 (1-3) ◽  
pp. 7-12 ◽  
Author(s):  
Gülseli Yıldırım ◽  
Metin Baştuğ ◽  
Ethem Akçıl ◽  
Hakan Fıçıcılar ◽  
Emine Koç ◽  
...  

2015 ◽  
Vol 30 (6) ◽  
pp. 1453-1463 ◽  
Author(s):  
Juliana Lenzi ◽  
Andre Felipe Rodrigues ◽  
Adriana de Sousa Rós ◽  
Bianca Blanski de Castro ◽  
Daniela Delwing de Lima ◽  
...  

2021 ◽  
Author(s):  
Gu-Choul Shin ◽  
Hyeong Min Lee ◽  
Na Yeon Kim ◽  
Sang-Ku Yoo ◽  
Yun Sun Park ◽  
...  

AbstractLimited therapeutic agents have been developed for non-alcoholic steatohepatitis (NASH), a common immunometabolic disease that can progress to hepatic cirrhosis and cancer. Glabridin and its derivatives are potential therapeutics for some metabolic diseases. However, the therapeutic effects of glabridin and its derivatives on NASH and their biological functions are unclear. This study demonstrated the role of synthetic glabridin derivatives (SGDs) in alleviating hepatic steatosis and inflammation in a biopsy-confirmed rodent NASH model. SGDs exerted therapeutic effects by activating autophagy and the antioxidant defense system, which mitigate NASH pathogenesis. The cellular target of HSG4112, an SGD, was paraoxonase 2. These findings will enable the development of novel therapeutics for NASH in the future.


2018 ◽  
Vol 22 (2) ◽  
pp. 255-264 ◽  
Author(s):  
Georgia B. Pompeu ◽  
Vivian C. Pietrobon ◽  
Cristiane C. F. Andreote ◽  
Luiz F. R. Ferreira ◽  
Mario Aguiar ◽  
...  

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