A novel amino acid functionalized ionic liquid promoted one-pot solvent-free synthesis of 3,4-dihydropyrimidin-2-(1H)-thiones

2012 ◽  
Vol 39 (3) ◽  
pp. 1335-1342 ◽  
Author(s):  
Parasuraman Karthikeyan ◽  
Sythana Suresh Kumar ◽  
Aswar Sachin Arunrao ◽  
Muskawar Prashant Narayan ◽  
Pundlik Rambhau Bhagat
Keyword(s):  
Ionic Liquid ◽  
Amino Acid ◽  
Solvent Free ◽  
One Pot ◽  
Functionalized Ionic Liquid ◽  
Solvent Free Synthesis

ChemInform Abstract: Highly Efficient, One-Pot, Solvent-Free Synthesis of 2,4,6-Triarylpyridines Using a Broensted-Acidic Ionic Liquid as Reusable Catalyst.

ChemInform ◽  
2010 ◽  
Vol 42 (1) ◽  
pp. no-no
Author(s):  
Abolghasem Davoodnia ◽  
Mehdi Bakavoli ◽  
Raheleh Moloudi ◽  
Niloofar Tavakoli-Hoseini ◽  
Maryam Khashi
Keyword(s):  
Ionic Liquid ◽  
Solvent Free ◽  
Reusable Catalyst ◽  
One Pot ◽  
Acidic Ionic Liquid ◽  
Highly Efficient ◽  
Solvent Free Synthesis

scholarly journals Solvent-Free Synthesis and Antiviral Activity of Chiral Dialkyl 2-(Substituted-((4-(Pyridin-3-Yl)Pyrimidin-2-Yl)Amino)Methyl) Malonate

2018 ◽  
Vol 42 (8) ◽  
pp. 428-433 ◽  
Author(s):  
Song Bai ◽  
Shan Liu ◽  
Yunying Zhu ◽  
Jiali Lu ◽  
Lina Ai ◽  
...  
Keyword(s):  
Amino Acid ◽  
Antiviral Activity ◽  
Asymmetric Synthesis ◽  
Amino Acid Ester ◽  
Solvent Free ◽  
One Pot ◽  
Methyl Malonate ◽  
Antiviral Activities ◽  
High Yields ◽  
Solvent Free Synthesis

An efficient asymmetric synthesis of chiral β-amino acid ester derivatives containing a 4-(pyridin-3-yl)pyrimidin-2-yl amine moiety was developed. This catalytic asymmetric Mannich reaction gave target products in high yields (95%) and excellent enantioselectivities (>99% ee) using a cinchona-based squaramide catalyst under solvent-free, one-pot conditions. Antiviral bioassays indicated that some of the chiral products exhibited higher antiviral activities against tobacco mosaic virus than the commercial compound ribavirin.

Solvent-free synthesis of 6-unsubstituted dihydropyrimidinones using 2-pyrrolidonium bisulphate as efficient catalyst

2016 ◽  
Vol 70 (8) ◽  
Author(s):  
Heshmatollah Alinezhad ◽  
Mahmood Tajbakhsh ◽  
Mahboobeh Zare ◽  
Mahbooeh Mousavi
Keyword(s):  
Ionic Liquid ◽  
Reaction Time ◽  
Organic Solvents ◽  
Simple Procedure ◽  
Solvent Free ◽  
One Pot ◽  
Efficient Catalyst ◽  
Short Reaction Time ◽  
Acidic Ionic Liquid ◽  
Solvent Free Synthesis

AbstractA one-pot three-component Biginelli-like reaction of enaminones, aldehydes with urea/thiourea in the presence of 2-pyrrolidonium bisulphate as an acidic ionic liquid catalyst for the preparation of 6-unsubstituted dihydropyrimidinones is described. The excellent yield, short reaction time, simple procedure and avoidance of the use of organic solvents are some advantages of this method.

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