scholarly journals Environmental exposure to persistent organic pollutants measured in breast milk of lactating women from an urban area in central Poland

2020 ◽  
Author(s):  
Peter Grešner ◽  
Marek Zieliński ◽  
Danuta Ligocka ◽  
Kinga Polańska ◽  
Wojciech Wąsowicz ◽  
...  
Keyword(s):  
High Resolution ◽  
Urban Area ◽  
Environmental Exposure ◽  
High Resolution Mass Spectrometry ◽  
Environmental Pollutants ◽  
World Health ◽  
Related Factors ◽  
High Resolution Gas Chromatography ◽  
Health Organization ◽  
Toxicity Equivalent

Abstract Mothers’ milk is considered a channel by means of which new-borns are exposed to polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and dioxin-like polychlorinated biphenyls (dl-PCBs), environmental pollutants entering food chain and accumulating in fat-rich tissues. In this study, the concentrations of selected PCDDs, PCDFs, and dl-PCBs (a total of 29 substances) in milk samples of 110 breast-feeding women from an urban area were analyzed using the high-resolution gas chromatography/high-resolution mass spectrometry method. Environmental exposure to these substances was expressed by means of the World Health Organization Toxicity Equivalent (WHO-TEQ2005) using the Toxicity Equivalent Factor values from van der Berg et al. (Toxicol. Sci. 93: 223-241, 2006). Concentrations and WHO-TEQ2005 values were then searched for plausible relationships with selected demographic and diet-related factors. The total WHO-TEQ2005 toxicity equivalent for all 29 substances was (mean ± SD) 10.57 ± 4.57 pg/g fat, while the WHO-TEQ2005 levels of PCDDs/PCDFs and dl-PCBs were 7.90 ± 4.17 pg/g fat and 2.67 ± 1.36 pg/g fat, respectively. The concentration and WHO-TEQ2005 toxicity equivalent of dl-PCBs correlated significantly with the mothers’ age (rP = 0.3814, p < 0.00005; rP = 0.2817, p < 0.005, respectively). The total WHO-TEQ2005 toxicity equivalent for all analyzed substances was found to be positively associated with the frequency of consumption of fish and dairy products (p < 0.05 for both associations). These outcomes must, however, be interpreted cautiously due to limited size of the study. The results of this paper may provide a basis for further studies on the exposure to PCDDs, PCDFs, and dl-PCBs, and mechanisms underlying their action.

Obstacles to Claiming Permanence and Injury-Relatedness for “Posttraumatic” Headache

2009 ◽  
Vol 14 (3) ◽  
pp. 3-6
Author(s):  
Robert J. Barth
Keyword(s):  
Complete Recovery ◽  
World Health ◽  
Related Factors ◽  
Posttraumatic Headache ◽  
Sixth Edition ◽  
Causative Relationship ◽  
Short Period ◽  
The One ◽  
Health Organization ◽  
Subjective Reports

Abstract “Posttraumatic” headaches claims are controversial because they are subjective reports often provided in the complex of litigation, and the underlying pathogenesis is not defined. This article reviews principles and scientific considerations in the AMAGuides to the Evaluation of Permanent Impairment (AMA Guides) that should be noted by evaluators who examine such cases. Some examples in the AMA Guides, Sixth Edition, may seem to imply that mild head trauma can cause permanent impairment due to headache. The author examines scientific findings that present obstacles to claiming that concussion or mild traumatic brain injury is a cause of permanent headache. The World Health Organization, for example, found a favorable prognosis for posttraumatic headache, and complete recovery over a short period of time was the norm. Other studies have highlighted the lack of a dose-response correlation between trauma and prolonged headache complaints, both in terms of the frequency and the severity of trauma. On the one hand, scientific studies have failed to support the hypothesis of a causative relationship between trauma and permanent or prolonged headaches; on the other hand, non–trauma-related factors are strongly associated with complaints of prolonged headache.

scholarly journals Knowledge of HIV and benefits of male medical circumcision amongst clients in an urban area

2014 ◽  
Vol 6 (1) ◽  
Author(s):  
Abidemi Faleye
Keyword(s):  
Urban Area ◽  
Hiv Transmission ◽  
World Health ◽  
Routine Practice ◽  
Cross Sectional ◽  
Innovative Methods ◽  
Validated Questionnaire ◽  
Preventative Strategy ◽  
Set Up ◽  
Health Organization

Background: Male medical circumcision (MMC) has been shown to reduce the risk of HIV transmission in circumcised men by up to 60%. Following recommendations from the World Health Organization, South Africa adopted MMC as a preventative strategy against HIV in 2010 and set up circumcision camps across the country. Concerns have been raised about condom avoidance following MMC because of a mistaken belief about the benefits of MMC.Aim and setting: The aim of this study was to describe the profile and knowledge about HIV and circumcision amongst men presenting for MMC in an urban area in KwaZulu-Natal.Methods: This was a cross-sectional descriptive study of 394 clients over the age of 18 years who presented to two MMC sites in Durban between November 2012 and March 2013. A validated questionnaire was used to collect data.Results: The mean age of clients presenting for MMC was 28 years. Most clients were black, single, unemployed and sexually active. The majority presented for MMC because they believed that MMC would reduce their risk of acquiring HIV infection. Knowledge about HIV transmission was very good and 86.3% of clients were aware that risky sexual behaviour suchas condom avoidance could reverse the benefits of MMC.Conclusion: The knowledge of HIV and benefits of MMC was very good amongst those presenting for MMC. However as MMC is primarily a preventative strategy, innovative methods to promote MMC prior to first sexual encounter need to be explored. Further research is needed to determine whether the benefits of MMC on the reduction of HIV transmission aresustained in routine practice. [Full text article to follow]

scholarly journals Survey of hearing disorders in an urban population in Rondonia, Northern Brazil

2013 ◽  
Vol 47 (2) ◽  
pp. 309-315 ◽  
Author(s):  
Maria Cecilia Bevilacqua ◽  
Marcos Roberto Banhara ◽  
Ariadnes Nobrega de Oliveira ◽  
Adriane Lima Mortari Moret ◽  
Katia de Freitas Alvarenga ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Hearing Impairment ◽  
Urban Area ◽  
Pure Tone Audiometry ◽  
Household Survey ◽  
World Health ◽  
Hearing Disorders ◽  
Cross Sectional ◽  
Northern Brazil ◽  
Health Organization

OBJECTIVE: To identify the prevalence of hearing loss for the population in the urban area. METHODS: A cross-sectional household survey based on the World Health Organization Ear and Hearing Disorders Survey Protocol was conducted in 298 households in the urban area of Monte Negro, Rondonia, Northern Brazil, from 2005 to 2007. Ear examinations, behavioral audiometry and pure tone audiometry were conducted on 577 individuals. RESULTS: The results showed that 3.8% (95%CI 2.17;5.45) of population were classified in the disabling hearing impairment category. The prevalence of moderate hearing impairment was 3.4%; severe impairment was 0.4%; and profound hearing impairment was not found. CONCLUSIONS: The impairing hearing loss prevalence found in this study is within of the international prevalence for this level of hearing loss and smaller than observed in a previous study in the South region of Brazil.

Robson Classification and quality audit

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Gehanath Baral
Keyword(s):  
Cesarean Section ◽  
World Health Organization ◽  
Real Time ◽  
Perinatal Outcome ◽  
World Health ◽  
Related Factors ◽  
Quality Audit ◽  
Robson Classification ◽  
Health Organization

World Health Organization has recommended Robson Classification from baseline obstetric characters to assess, monitor and compare Cesarean Section rates by the quantity analysis. Incorporation of real time labor related factors requires quality audit for both maternal and perinatal outcome.

scholarly journals Connecting environmental exposure and neurodegeneration using cheminformatics and high resolution mass spectrometry: potential and challenges

2019 ◽  
Vol 21 (9) ◽  
pp. 1426-1445 ◽  
Author(s):  
Emma L. Schymanski ◽  
Nancy C. Baker ◽  
Antony J. Williams ◽  
Randolph R. Singh ◽  
Jean-Pierre Trezzi ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
High Resolution ◽  
Environmental Exposure ◽  
Environmental Assessment ◽  
Medical Information ◽  
High Resolution Mass Spectrometry ◽  
High Resolution Mass ◽  
Disciplinary Perspective ◽  
Interactive Resources ◽  
Resolution Mass

A multi-disciplinary perspective on connecting chemistry, exposure and medical information to “neurotoxicity” for mass spectrometry-based environmental assessment, including multiple interactive resources for readers to use and explore.

Epidemiology of overweight and obesity among Italian early adolescents: relation with physical activity and sedentary behaviour

2005 ◽  
Vol 14 (2) ◽  
pp. 100-107 ◽  
Author(s):  
Alessio Vieno ◽  
Massimo Santinello ◽  
Maria Cristiana Martin
Keyword(s):  
Physical Activity ◽  
Sedentary Behaviour ◽  
Early Adolescents ◽  
Overweight And Obesity ◽  
World Health ◽  
National Study ◽  
Related Factors ◽  
School Aged Children ◽  
Health Organization ◽  
The University

SUMMARYAims – The prevalence of overweight and obesity and the role of possible related factors were analysed among Italian early adolescents. Method – The survey reported here is part of the larger “Health Behaviour in School Aged Children” (HBSC) trans-national study, which is co-ordinated by the European Office of the World Health Organization. The data were gathered through self-administered questionnaires filled out by a representative sample of 4,386 (48.4% males) Italian students (11-, 13- and 15-year old). Results – The overall prevalence is 16.7% for overweight and 2.5% for obesity. Boys are more at risk than girls for the two phenomena. Moreover, age group, mother's education, area of residence, physical activity, and sedentary behaviour show a significant association with both outcomes. Conclusion – Findings of the present study are in agreement with similar studies carried out on early adolescents population, showing that prevalence in overweight and obesity decreases during this phase and is more diffused among boys than girls. The prevalence of both diseases is higher in the South and Islands. Sedentary behaviour and physical activity are substantive factors which preventive interventions could act on.Declaration of Interest: the HBSC study is partly funded by the University of Padova through a scholarship attributed to Dr. Alessio Vieno (Year 2001 – prot. CPDR013233).

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